DrugDashboards

Janumet Xr

sitagliptin and metformin hydrochloride · SITAGLIPTIN PHOSPHATE 50 mg/1; METFORMIN HYDROCHLORIDE 500 mg/1 · Tablet, Film Coated, Extended Release · Oral · Merck Sharp & Dohme LLC

NDC 00006-0078-61 · 60 TABLET, FILM COATED, EXTENDED RELEASE in 1 BOTTLE · NDA · View full market →

The short version

5 companies supply this market — a reasonable cushion if one runs into trouble. The price has held steady around $5.28 per unit over the past year. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$5.28per EAinvoice-surveyed acquisition cost · Aug 19, 2026
  • Part D plans paid (avg)$12.17per dosage unitgross, before rebates — matched by drug name · 2024
  • Part D point of sale (median)$5.28per unitnegotiated price across 5,232 plans — before rebates · Apr 1, 2026
  • Federal ceiling (Big4)$4.41per unitMerck Sharp & Dohme LLC · Jan 1, 202683% of what pharmacies pay — a deeper discount than 57% of drugs with this benchmark

Medicare Part D

All Part D pricing →
ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$5.28per unit
middle half $5.21$5.50 · 5,232 plans · Apr 1, 2026
Est. net of rebates
$3.17–$3.96
brand drug — est. 25-40% rebate off the price at left
Coverage & restrictions
95%of plans cover it
tier 3 · prior auth 0% · step therapy 0% · qty limit 98%

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.

NADAC price per unit

$0$5.00$10.00Aug 2013Sep 2026$5.28
51 price points · per EASource: CMS NADAC

Estimated fill cost

#30 count
$158.48
#90 count
$475.44

Estimates: latest NADAC unit price × quantity. Pharmacy acquisition cost only — excludes dispensing fees, markup, and insurance terms.

Medicaid spend (2025)

$1.3M
3,927 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

5Low risk

Some pressure is visible, but not much — here’s everything the score found to count.

  • 5 active manufacturers+5

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for sitagliptin and metformin hydrochloride (oral solid) in the next 90 days

sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Regulatory

Application
NDA202270
TE code
AB
Approval date
Feb 2, 2012
Patents / exclusivity
6 patents, 0 exclusivities
TypeNumber / codeExpires
patent7326708*PEDMay 24, 2027
patent7326708*PEDMay 24, 2027
patent7326708*PEDMay 24, 2027
patent7326708Nov 24, 2026
patent7326708Nov 24, 2026
patent7326708Nov 24, 2026

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of sitagliptin and metformin hydrochloride (Tablet, Film Coated, Extended Release)

LabelerStrengthFirst seenLast seen
Zydus Lifesciences LimitedSITAGLIPTIN 50 mg/1; METFORMIN HYDROCHLORIDE 500 mg/1Aug 26, 2026Sep 3, 2026
Zydus Lifesciences LimitedSITAGLIPTIN 50 mg/1; METFORMIN HYDROCHLORIDE 1000 mg/1Aug 26, 2026Sep 3, 2026
Zydus Pharmaceuticals USA Inc.SITAGLIPTIN 100 mg/1; METFORMIN HYDROCHLORIDE 1000 mg/1Aug 26, 2026Sep 3, 2026
Zydus Pharmaceuticals USA Inc.SITAGLIPTIN 50 mg/1; METFORMIN HYDROCHLORIDE 1000 mg/1Aug 26, 2026Sep 3, 2026
A-S Medication SolutionsSITAGLIPTIN PHOSPHATE 50 mg/1; METFORMIN HYDROCHLORIDE 1000 mg/1Aug 26, 2026Sep 2, 2026
Merck Sharp & Dohme LLCSITAGLIPTIN PHOSPHATE 100 mg/1; METFORMIN HYDROCHLORIDE 1000 mg/1Aug 26, 2026Sep 2, 2026
Merck Sharp & Dohme LLCSITAGLIPTIN PHOSPHATE 50 mg/1; METFORMIN HYDROCHLORIDE 500 mg/1Aug 26, 2026Sep 2, 2026
Merck Sharp & Dohme LLCSITAGLIPTIN PHOSPHATE 50 mg/1; METFORMIN HYDROCHLORIDE 1000 mg/1Aug 26, 2026Sep 2, 2026
Par Health USA, LLCSITAGLIPTIN PHOSPHATE 50 mg/1; METFORMIN HYDROCHLORIDE 1000 mg/1Aug 26, 2026Sep 2, 2026
Par Health USA, LLCSITAGLIPTIN PHOSPHATE 50 mg/1; METFORMIN HYDROCHLORIDE 500 mg/1Aug 26, 2026Sep 2, 2026
Par Health USA, LLCSITAGLIPTIN PHOSPHATE 100 mg/1; METFORMIN HYDROCHLORIDE 1000 mg/1Aug 26, 2026Sep 2, 2026
Zydus Pharmaceuticals USA Inc.SITAGLIPTIN 50 mg/1; METFORMIN HYDROCHLORIDE 500 mg/1Aug 26, 2026Aug 31, 2026
Zydus Lifesciences LimitedSITAGLIPTIN 100 mg/1; METFORMIN HYDROCHLORIDE 1000 mg/1Aug 26, 2026Aug 28, 2026
Zydus Lifesciences LimitedSITAGLIPTIN 1000 mg/1; METFORMIN HYDROCHLORIDE 50 mg/1Jul 22, 2026Aug 23, 2026
Par Health USA, LLCSITAGLIPTIN PHOSPHATE 500 mg/1; METFORMIN HYDROCHLORIDE 50 mg/1Jul 25, 2026Aug 22, 2026
Par Health USA, LLCSITAGLIPTIN PHOSPHATE 1000 mg/1; METFORMIN HYDROCHLORIDE 100 mg/1Jul 25, 2026Aug 22, 2026
Par Health USA, LLCSITAGLIPTIN PHOSPHATE 1000 mg/1; METFORMIN HYDROCHLORIDE 50 mg/1Jul 25, 2026Aug 22, 2026
Zydus Lifesciences LimitedSITAGLIPTIN 500 mg/1; METFORMIN HYDROCHLORIDE 50 mg/1Jul 22, 2026Aug 22, 2026
Zydus Pharmaceuticals USA Inc.SITAGLIPTIN 500 mg/1; METFORMIN HYDROCHLORIDE 50 mg/1Jul 22, 2026Aug 22, 2026
Zydus Lifesciences LimitedSITAGLIPTIN 1000 mg/1; METFORMIN HYDROCHLORIDE 100 mg/1Jul 22, 2026Aug 21, 2026
Zydus Pharmaceuticals USA Inc.SITAGLIPTIN 1000 mg/1; METFORMIN HYDROCHLORIDE 50 mg/1Jul 22, 2026Aug 21, 2026
A-S Medication SolutionsSITAGLIPTIN PHOSPHATE 1000 mg/1; METFORMIN HYDROCHLORIDE 50 mg/1Jul 22, 2026Aug 19, 2026
Merck Sharp & Dohme LLCSITAGLIPTIN PHOSPHATE 500 mg/1; METFORMIN HYDROCHLORIDE 50 mg/1Jul 22, 2026Aug 19, 2026
Merck Sharp & Dohme LLCSITAGLIPTIN PHOSPHATE 1000 mg/1; METFORMIN HYDROCHLORIDE 100 mg/1Jul 22, 2026Aug 19, 2026
Merck Sharp & Dohme LLCSITAGLIPTIN PHOSPHATE 1000 mg/1; METFORMIN HYDROCHLORIDE 50 mg/1Jul 22, 2026Aug 19, 2026
Zydus Pharmaceuticals USA Inc.SITAGLIPTIN 1000 mg/1; METFORMIN HYDROCHLORIDE 100 mg/1Jul 22, 2026Aug 19, 2026
Zydus Lifesciences LimitedMETFORMIN HYDROCHLORIDE 500 mg/1; SITAGLIPTIN 50 mg/1Jul 15, 2026Jul 19, 2026
Zydus Pharmaceuticals USA Inc.METFORMIN HYDROCHLORIDE 500 mg/1; SITAGLIPTIN 50 mg/1Jul 15, 2026Jul 19, 2026
Zydus Pharmaceuticals USA Inc.METFORMIN HYDROCHLORIDE 1000 mg/1; SITAGLIPTIN 100 mg/1Jul 15, 2026Jul 19, 2026
Zydus Lifesciences LimitedMETFORMIN HYDROCHLORIDE 1000 mg/1; SITAGLIPTIN 100 mg/1Jul 15, 2026Jul 18, 2026
Zydus Pharmaceuticals USA Inc.METFORMIN HYDROCHLORIDE 1000 mg/1; SITAGLIPTIN 50 mg/1Jul 15, 2026Jul 18, 2026
A-S Medication SolutionsMETFORMIN HYDROCHLORIDE 1000 mg/1; SITAGLIPTIN PHOSPHATE 50 mg/1Jul 15, 2026Jul 15, 2026
Merck Sharp & Dohme LLCMETFORMIN HYDROCHLORIDE 1000 mg/1; SITAGLIPTIN PHOSPHATE 100 mg/1Jul 15, 2026Jul 15, 2026
Merck Sharp & Dohme LLCMETFORMIN HYDROCHLORIDE 1000 mg/1; SITAGLIPTIN PHOSPHATE 50 mg/1Jul 15, 2026Jul 15, 2026
Merck Sharp & Dohme LLCMETFORMIN HYDROCHLORIDE 500 mg/1; SITAGLIPTIN PHOSPHATE 50 mg/1Jul 15, 2026Jul 15, 2026
Zydus Lifesciences LimitedMETFORMIN HYDROCHLORIDE 1000 mg/1; SITAGLIPTIN 50 mg/1Jul 15, 2026Jul 15, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Janumet Xr — NDC 00006-0078-61," retrieved September 3, 2026, https://drugdashboards.com/drug/00006007861.

Free to cite with attribution — see how the data is put together.