The short version
5 companies supply this market — a reasonable cushion if one runs into trouble.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
Sitagliptin and Metformin hydrochloride
sitagliptin and metformin hydrochloride · SITAGLIPTIN PHOSPHATE 100 mg/1; METFORMIN HYDROCHLORIDE 1000 mg/1 · Tablet, Film Coated, Extended Release · Oral · Par Health USA, LLC
NDC 10370-0351-11 · 30 TABLET, FILM COATED, EXTENDED RELEASE in 1 BOTTLE, PLASTIC · ANDA · View full market →
Medicare Part D
All Part D pricing →Matched to CMS's representative package for this drug (NDC 00006-0081-31) — same generic, strength, and dosage form. CMS prices one NDC per drug concept, not every package.
ⓘ How this was built
Data sources
- CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method
Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.
Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.
Plans pay at point of saleⓘ
$10.56per unit
middle half $10.41–$11.11 · 5,232 plans · Apr 1, 2026
Est. net of rebatesⓘ
≈ $10.56
generic — rebates are minimal, so net ≈ gross
Coverage & restrictions
95%of plans cover it
tier 3 · prior auth 0% · step therapy 0% · qty limit 97%
*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.
NADAC price per unit
No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.
Supply fragility
Not scored — fragility is computed for NADAC-priced NDCs.
90-day shortage risk (model v2)
0.1%chance of a new FDA shortage posting for sitagliptin and metformin hydrochloride (oral solid) in the next 90 days
sole-source market
For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.
Backtested statistical model over the whole market, not this package alone. Model details →
Regulatory
- Application
- ANDA204144
- TE code
- AB
- Approval date
- Jun 4, 2025
- Patents / exclusivity
- None on file
Shortage history
No FDA shortage reports for this drug or its presentations.
Recalls (this NDC)
No enforcement reports list this package NDC.
Manufacturers of sitagliptin and metformin hydrochloride (Tablet, Film Coated, Extended Release)
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| Zydus Lifesciences Limited | SITAGLIPTIN 50 mg/1; METFORMIN HYDROCHLORIDE 500 mg/1 | Aug 26, 2026 | Sep 3, 2026 |
| Zydus Lifesciences Limited | SITAGLIPTIN 50 mg/1; METFORMIN HYDROCHLORIDE 1000 mg/1 | Aug 26, 2026 | Sep 3, 2026 |
| Zydus Pharmaceuticals USA Inc. | SITAGLIPTIN 100 mg/1; METFORMIN HYDROCHLORIDE 1000 mg/1 | Aug 26, 2026 | Sep 3, 2026 |
| Zydus Pharmaceuticals USA Inc. | SITAGLIPTIN 50 mg/1; METFORMIN HYDROCHLORIDE 1000 mg/1 | Aug 26, 2026 | Sep 3, 2026 |
| A-S Medication Solutions | SITAGLIPTIN PHOSPHATE 50 mg/1; METFORMIN HYDROCHLORIDE 1000 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Merck Sharp & Dohme LLC | SITAGLIPTIN PHOSPHATE 100 mg/1; METFORMIN HYDROCHLORIDE 1000 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Merck Sharp & Dohme LLC | SITAGLIPTIN PHOSPHATE 50 mg/1; METFORMIN HYDROCHLORIDE 500 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Merck Sharp & Dohme LLC | SITAGLIPTIN PHOSPHATE 50 mg/1; METFORMIN HYDROCHLORIDE 1000 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Par Health USA, LLC | SITAGLIPTIN PHOSPHATE 50 mg/1; METFORMIN HYDROCHLORIDE 1000 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Par Health USA, LLC | SITAGLIPTIN PHOSPHATE 50 mg/1; METFORMIN HYDROCHLORIDE 500 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Par Health USA, LLC | SITAGLIPTIN PHOSPHATE 100 mg/1; METFORMIN HYDROCHLORIDE 1000 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Zydus Pharmaceuticals USA Inc. | SITAGLIPTIN 50 mg/1; METFORMIN HYDROCHLORIDE 500 mg/1 | Aug 26, 2026 | Aug 31, 2026 |
| Zydus Lifesciences Limited | SITAGLIPTIN 100 mg/1; METFORMIN HYDROCHLORIDE 1000 mg/1 | Aug 26, 2026 | Aug 28, 2026 |
| Zydus Lifesciences Limited | SITAGLIPTIN 1000 mg/1; METFORMIN HYDROCHLORIDE 50 mg/1 | Jul 22, 2026 | Aug 23, 2026 |
| Par Health USA, LLC | SITAGLIPTIN PHOSPHATE 500 mg/1; METFORMIN HYDROCHLORIDE 50 mg/1 | Jul 25, 2026 | Aug 22, 2026 |
| Par Health USA, LLC | SITAGLIPTIN PHOSPHATE 1000 mg/1; METFORMIN HYDROCHLORIDE 100 mg/1 | Jul 25, 2026 | Aug 22, 2026 |
| Par Health USA, LLC | SITAGLIPTIN PHOSPHATE 1000 mg/1; METFORMIN HYDROCHLORIDE 50 mg/1 | Jul 25, 2026 | Aug 22, 2026 |
| Zydus Lifesciences Limited | SITAGLIPTIN 500 mg/1; METFORMIN HYDROCHLORIDE 50 mg/1 | Jul 22, 2026 | Aug 22, 2026 |
| Zydus Pharmaceuticals USA Inc. | SITAGLIPTIN 500 mg/1; METFORMIN HYDROCHLORIDE 50 mg/1 | Jul 22, 2026 | Aug 22, 2026 |
| Zydus Lifesciences Limited | SITAGLIPTIN 1000 mg/1; METFORMIN HYDROCHLORIDE 100 mg/1 | Jul 22, 2026 | Aug 21, 2026 |
| Zydus Pharmaceuticals USA Inc. | SITAGLIPTIN 1000 mg/1; METFORMIN HYDROCHLORIDE 50 mg/1 | Jul 22, 2026 | Aug 21, 2026 |
| A-S Medication Solutions | SITAGLIPTIN PHOSPHATE 1000 mg/1; METFORMIN HYDROCHLORIDE 50 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Merck Sharp & Dohme LLC | SITAGLIPTIN PHOSPHATE 500 mg/1; METFORMIN HYDROCHLORIDE 50 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Merck Sharp & Dohme LLC | SITAGLIPTIN PHOSPHATE 1000 mg/1; METFORMIN HYDROCHLORIDE 100 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Merck Sharp & Dohme LLC | SITAGLIPTIN PHOSPHATE 1000 mg/1; METFORMIN HYDROCHLORIDE 50 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Zydus Pharmaceuticals USA Inc. | SITAGLIPTIN 1000 mg/1; METFORMIN HYDROCHLORIDE 100 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Zydus Lifesciences Limited | METFORMIN HYDROCHLORIDE 500 mg/1; SITAGLIPTIN 50 mg/1 | Jul 15, 2026 | Jul 19, 2026 |
| Zydus Pharmaceuticals USA Inc. | METFORMIN HYDROCHLORIDE 500 mg/1; SITAGLIPTIN 50 mg/1 | Jul 15, 2026 | Jul 19, 2026 |
| Zydus Pharmaceuticals USA Inc. | METFORMIN HYDROCHLORIDE 1000 mg/1; SITAGLIPTIN 100 mg/1 | Jul 15, 2026 | Jul 19, 2026 |
| Zydus Lifesciences Limited | METFORMIN HYDROCHLORIDE 1000 mg/1; SITAGLIPTIN 100 mg/1 | Jul 15, 2026 | Jul 18, 2026 |
| Zydus Pharmaceuticals USA Inc. | METFORMIN HYDROCHLORIDE 1000 mg/1; SITAGLIPTIN 50 mg/1 | Jul 15, 2026 | Jul 18, 2026 |
| A-S Medication Solutions | METFORMIN HYDROCHLORIDE 1000 mg/1; SITAGLIPTIN PHOSPHATE 50 mg/1 | Jul 15, 2026 | Jul 15, 2026 |
| Merck Sharp & Dohme LLC | METFORMIN HYDROCHLORIDE 1000 mg/1; SITAGLIPTIN PHOSPHATE 100 mg/1 | Jul 15, 2026 | Jul 15, 2026 |
| Merck Sharp & Dohme LLC | METFORMIN HYDROCHLORIDE 1000 mg/1; SITAGLIPTIN PHOSPHATE 50 mg/1 | Jul 15, 2026 | Jul 15, 2026 |
| Merck Sharp & Dohme LLC | METFORMIN HYDROCHLORIDE 500 mg/1; SITAGLIPTIN PHOSPHATE 50 mg/1 | Jul 15, 2026 | Jul 15, 2026 |
| Zydus Lifesciences Limited | METFORMIN HYDROCHLORIDE 1000 mg/1; SITAGLIPTIN 50 mg/1 | Jul 15, 2026 | Jul 15, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
Cite this page
DrugDashboards, "Sitagliptin and Metformin hydrochloride — NDC 10370-0351-11," retrieved September 3, 2026, https://drugdashboards.com/drug/10370035111.
Free to cite with attribution — see how the data is put together.