DrugDashboards

Zepatier

elbasvir and grazoprevir · ELBASVIR 50 mg/1; GRAZOPREVIR ANHYDROUS 100 mg/1 · Tablet, Film Coated · Oral · Merck Sharp & Dohme LLC

NDC 00006-3074-02 · 2 DOSE PACK in 1 CARTON / 14 TABLET, FILM COATED in 1 DOSE PACK · NDA · View full market →

The short version

Just 2 companies supply this market — thin enough that a single exit would be felt immediately.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Part D plans paid (avg)$249.61per dosage unitgross, before rebates — matched by drug name · 2024
  • Part D point of sale (median)$266.43per unitnegotiated price across 86 plans — before rebates · Jan 1, 2026
  • Federal ceiling (Big4)$111.66per unitMerck Sharp & Dohme LLC · Jan 1, 2026

Medicare Part D

All Part D pricing →
ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$266.43per unit
middle half $258.50$266.43 · 86 plans · Jan 1, 2026
Est. net of rebates
$159.86–$199.82
brand drug — est. 25-40% rebate off the price at left
Coverage & restrictions
2%of plans cover it
tier 5 · prior auth 100% · step therapy 0% · qty limit 2%

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 9 quarters since 2024.

NADAC price per unit

$0$250.00$500.00$750.00Jun 2017Jun 2017$634.24
1 price point · per · last surveyed Invalid DateSource: CMS NADAC

Estimated fill cost

WAC per package, as filed
$7,280.00
Reported to Texas DSHS · 2026 annual filing · Merck Sharp & Dohme LLC

Manufacturer list price as filed — not what pharmacies actually pay after discounts.

Supply fragility

Not scored — fragility is computed for NADAC-priced NDCs.

Is this a "specialty" drug?

There's no legal definition — it meets 2 of 6 public criteria. Why that matters →

  • Part D specialty tier · median tier 5 across plans
  • Costs ≥ $950/fill · avg $6,989.11 per prescription
  • Biologic (BLA)
  • Injectable / infused
  • Orphan-drug exclusivity
  • REMS program

Regulatory

Application
NDA208261
TE code
Approval date
Jan 28, 2016
Patents / exclusivity
2 patents, 0 exclusivities
TypeNumber / codeExpires
patent8871759May 4, 2031
patent7973040Jul 24, 2029

Shortage history

  • Planned discontinuation Zepatier, Tablet, 50 mg; 100 mg (NDC 0006-3074-02)Oct 17, 2025

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of elbasvir and grazoprevir (Tablet, Film Coated)

LabelerStrengthFirst seenLast seen
Merck Sharp & Dohme LLCELBASVIR 50 mg/1; GRAZOPREVIR ANHYDROUS 100 mg/1Jul 15, 2026Sep 2, 2026
MSD International GmbHELBASVIR 50 mg/1; GRAZOPREVIR 100 mg/1Jul 15, 2026Sep 2, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Zepatier — NDC 00006-3074-02," retrieved September 3, 2026, https://drugdashboards.com/drug/00006307402.

Free to cite with attribution — see how the data is put together.