The short version
Just 2 companies supply this market — thin enough that a single exit would be felt immediately.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
imipenem and cilastatin sodium · IMIPENEM 500 mg/100mL; CILASTATIN SODIUM 500 mg/100mL · Injection, Powder, For Solution · Intravenous · Merck Sharp & Dohme LLC
NDC 00006-3516-59 · 25 VIAL, SINGLE-DOSE in 1 TRAY / 100 mL in 1 VIAL, SINGLE-DOSE · NDA · View full market →
Just 2 companies supply this market — thin enough that a single exit would be felt immediately.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.
Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.
Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.
Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.
Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.
*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 8 quarters since 2024.
No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.
Manufacturer list price as filed — not what pharmacies actually pay after discounts.
Not scored — fragility is computed for NADAC-priced NDCs.
There's no legal definition — it meets 1 of 6 public criteria. Why that matters →
No enforcement reports list this package NDC.
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| Fresenius Kabi USA, LLC | IMIPENEM 500 mg/20mL; CILASTATIN SODIUM 500 mg/20mL | Jul 22, 2026 | Sep 3, 2026 |
| Merck Sharp & Dohme LLC | IMIPENEM 500 mg/100mL; CILASTATIN SODIUM 500 mg/100mL | Jul 22, 2026 | Sep 2, 2026 |
| Fresenius Kabi USA, LLC | IMIPENEM 250 mg/20mL; CILASTATIN SODIUM 250 mg/20mL | Jul 22, 2026 | Aug 28, 2026 |
| Fresenius Kabi USA, LLC | CILASTATIN SODIUM 250 mg/20mL; IMIPENEM 250 mg/20mL | Jul 15, 2026 | Jul 18, 2026 |
| Fresenius Kabi USA, LLC | CILASTATIN SODIUM 500 mg/20mL; IMIPENEM 500 mg/20mL | Jul 15, 2026 | Jul 15, 2026 |
| Merck Sharp & Dohme LLC | CILASTATIN SODIUM 500 mg/100mL; IMIPENEM 500 mg/100mL | Jul 15, 2026 | Jul 15, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
DrugDashboards, "Primaxin Iv — NDC 00006-3516-59," retrieved September 3, 2026, https://drugdashboards.com/drug/00006351659.
Free to cite with attribution — see how the data is put together.