DrugDashboards

Restasis MultiDose

cyclosporine · CYCLOSPORINE .5 mg/mL · Emulsion · Ophthalmic · Allergan, Inc.

NDC 00023-5301-05 · 1 BOTTLE in 1 CARTON / 5.5 mL in 1 BOTTLE · NDA · View full market →

The short version

12 companies supply this market — deep enough that no single failure threatens the supply. The price has held steady around $112.32 per mL over the past year. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$112.32per MLinvoice-surveyed acquisition cost · Aug 19, 2026
  • Part D plans paid (avg)$111.94per dosage unitgross, before rebates — matched by drug name · 2024
  • Part D point of sale (median)$111.50per unitnegotiated price across 2,950 plans — before rebates · Apr 1, 2026
  • Federal ceiling (Big4)$483.26per package of 5.5MLAbbvie US LLC · Jan 1, 2026

Medicare Part D

All Part D pricing →
ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$111.50per unit
middle half $109.59$113.93 · 2,950 plans · Apr 1, 2026
Est. net of rebates
$66.90–$83.62
brand drug — est. 25-40% rebate off the price at left
Coverage & restrictions
54%of plans cover it
tier 3 · prior auth 0% · step therapy 0% · qty limit 72%

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.

NADAC price per unit

$0$50.00$100.00$150.00May 2017Sep 2026$112.32
42 price points · per MLSource: CMS NADAC

Estimated fill cost

WAC per package, as filed
$645.63
Reported to Texas DSHS · 2026 annual filing · Abbvie Inc

Manufacturer list price as filed — not what pharmacies actually pay after discounts.

Medicaid spend (2025)

$4.6M
7,346 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

0Low risk

Nothing here is signaling trouble: several manufacturers, no current shortage, no recent serious recalls, stable pricing. In drug supply, boring is the good outcome.

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for cyclosporine (other) in the next 90 days

OAI inspection at a producing facility (24 months) · sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Regulatory

Application
NDA050790
TE code
AB
Approval date
Dec 23, 2002
Patents / exclusivity
4 patents, 0 exclusivities
TypeNumber / codeExpires
patent9669974May 11, 2034
patent9676525Feb 7, 2034
patent8561859Apr 16, 2032
patent8292129Feb 25, 2031

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of cyclosporine (Emulsion)

LabelerStrengthFirst seenLast seen
Allergan, Inc.CYCLOSPORINE .5 mg/mLJul 15, 2026Sep 3, 2026
A-S Medication SolutionsCYCLOSPORINE .5 mg/mLJul 15, 2026Sep 2, 2026
Apotex CorpCYCLOSPORINE .5 mg/mLJul 15, 2026Sep 2, 2026
Devatis Inc.CYCLOSPORINE .5 mg/mLJul 15, 2026Sep 2, 2026
Harrow Eye, LLCCYCLOSPORINE 1 mg/mLJul 15, 2026Sep 2, 2026
Kvk-Tech, Inc.CYCLOSPORINE .5 mg/mLJul 15, 2026Sep 2, 2026
Lupin Pharmaceuticals, Inc.CYCLOSPORINE .5 mg/mLJul 15, 2026Sep 2, 2026
Mylan Pharmaceuticals Inc.CYCLOSPORINE .5 mg/mLJul 15, 2026Sep 2, 2026
Santen IncorporatedCYCLOSPORINE 1 mg/mLJul 15, 2026Sep 2, 2026
Saptalis Pharmaceuticals, LLCCYCLOSPORINE .5 mg/mLJul 15, 2026Sep 2, 2026
Teva Pharmaceuticals, Inc.CYCLOSPORINE .5 mg/mLJul 15, 2026Sep 2, 2026
Upsher-Smith Laboratories, LLCCYCLOSPORINE .5 mg/mLJul 15, 2026Sep 2, 2026
Amneal Pharmaceuticals NY LLCCYCLOSPORINE .5 mg/mLJul 15, 2026Jul 22, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Restasis MultiDose — NDC 00023-5301-05," retrieved September 3, 2026, https://drugdashboards.com/drug/00023530105.

Free to cite with attribution — see how the data is put together.