The short version
17 companies supply this market — deep enough that no single failure threatens the supply.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
misoprostol · MISOPROSTOL 100 ug/1 · Tablet · Oral · Pfizer Laboratories Div Pfizer Inc
NDC 00025-1451-60 · 60 TABLET in 1 BOTTLE, UNIT-DOSE · NDA · View full market →
17 companies supply this market — deep enough that no single failure threatens the supply.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.
Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.
Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.
Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.
Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.
*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.
No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.
Manufacturer list price as filed — not what pharmacies actually pay after discounts.
Not scored — fragility is computed for NADAC-priced NDCs.
price up 16% YoY · sole-source market
For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.
Backtested statistical model over the whole market, not this package alone. Model details →
There's no legal definition — it meets 1 of 6 public criteria. Why that matters →
No FDA shortage reports for this drug or its presentations.
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| American Health Packaging | MISOPROSTOL 200 ug/1 | Jul 15, 2026 | Sep 2, 2026 |
| American Health Packaging | MISOPROSTOL 100 ug/1 | Jul 15, 2026 | Sep 2, 2026 |
| ANI Pharmaceuticals, Inc. | MISOPROSTOL 100 ug/1 | Jul 15, 2026 | Sep 2, 2026 |
| ANI Pharmaceuticals, Inc. | MISOPROSTOL 200 ug/1 | Jul 15, 2026 | Sep 2, 2026 |
| AvPAK | MISOPROSTOL 200 ug/1 | Jul 15, 2026 | Sep 2, 2026 |
| Cardinal Health 107, LLC | MISOPROSTOL 200 ug/1 | Jul 15, 2026 | Sep 2, 2026 |
| Lupin Pharmaceuticals,Inc. | MISOPROSTOL 200 ug/1 | Jul 15, 2026 | Sep 2, 2026 |
| Lupin Pharmaceuticals,Inc. | MISOPROSTOL 100 ug/1 | Jul 15, 2026 | Sep 2, 2026 |
| Mylan Pharmaceuticals Inc. | MISOPROSTOL 100 ug/1 | Jul 15, 2026 | Sep 2, 2026 |
| Mylan Pharmaceuticals Inc. | MISOPROSTOL 200 ug/1 | Jul 15, 2026 | Sep 2, 2026 |
| Novel Laboratories, Inc. | MISOPROSTOL 100 ug/1 | Jul 15, 2026 | Sep 2, 2026 |
| Novel Laboratories, Inc. | MISOPROSTOL 200 ug/1 | Jul 15, 2026 | Sep 2, 2026 |
| NuCare Pharmaceuticals, Inc. | MISOPROSTOL 100 ug/1 | Jul 15, 2026 | Sep 2, 2026 |
| NuCare Pharmaceuticals,Inc. | MISOPROSTOL 200 ug/1 | Jul 15, 2026 | Sep 2, 2026 |
| PD-Rx Pharmaceuticals, Inc. | MISOPROSTOL 200 ug/1 | Jul 15, 2026 | Sep 2, 2026 |
| Pfizer Laboratories Div Pfizer Inc | MISOPROSTOL 200 ug/1 | Jul 15, 2026 | Sep 2, 2026 |
| Pfizer Laboratories Div Pfizer Inc | MISOPROSTOL 100 ug/1 | Jul 15, 2026 | Sep 2, 2026 |
| PharmPak, Inc. | MISOPROSTOL 200 ug/1 | Jul 15, 2026 | Sep 2, 2026 |
| Proficient Rx LP | MISOPROSTOL 200 ug/1 | Jul 15, 2026 | Sep 2, 2026 |
| Redpharm Drug | MISOPROSTOL 200 ug/1 | Jul 15, 2026 | Sep 2, 2026 |
| GenBioPro, Inc. | MISOPROSTOL 200 ug/1 | Jul 15, 2026 | Aug 31, 2026 |
| Bryant Ranch Prepack | MISOPROSTOL 100 ug/1 | Jul 15, 2026 | Aug 28, 2026 |
| Micro Labs Limited | MISOPROSTOL 200 ug/1 | Jul 15, 2026 | Aug 5, 2026 |
| Micro Labs Limited | MISOPROSTOL 100 ug/1 | Jul 15, 2026 | Aug 5, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
DrugDashboards, "Cytotec — NDC 00025-1451-60," retrieved September 3, 2026, https://drugdashboards.com/drug/00025145160.
Free to cite with attribution — see how the data is put together.