DrugDashboards

Mavyret

Glecaprevir and Pibrentasvir · PIBRENTASVIR 20 mg/1; GLECAPREVIR 50 mg/1 · Pellet · Oral · AbbVie Inc.

NDC 00074-2600-28 · 1 PACKET in 1 CARTON / 28 PELLET in 1 PACKET · NDA · View full market →

The short version

Only one company currently supplies this market — there is no backup if it stumbles.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Part D plans paid (avg)$155.84per dosage unitgross, before rebates — matched by drug name · 2024
  • Part D point of sale (median)$96.29per unitnegotiated price across 3,489 plans — before rebates · Apr 1, 2026
  • Federal ceiling (Big4)$70.58per unitAbbvie US LLC · Jan 1, 2026

Medicare Part D

All Part D pricing →
ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$96.29per unit
middle half $94.16$98.35 · 3,489 plans · Apr 1, 2026
Est. net of rebates
$57.77–$72.21
brand drug — est. 25-40% rebate off the price at left
Coverage & restrictions
63%of plans cover it
tier 5 · prior auth 97% · step therapy 0% · qty limit 49%

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.

NADAC price per unit

No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.

Estimated fill cost

WAC per package, as filed
$2,640.12
Reported to Texas DSHS · 2026 annual filing · Abbvie Inc

Manufacturer list price as filed — not what pharmacies actually pay after discounts.

Medicaid spend (2025)

$340,185
47 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

Not scored — fragility is computed for NADAC-priced NDCs.

Is this a "specialty" drug?

There's no legal definition — it meets 3 of 6 public criteria. Why that matters →

  • Part D specialty tier · median tier 5 across plans
  • Costs ≥ $950/fill · avg $13,271.38 per prescription
  • Biologic (BLA)
  • Injectable / infused
  • Orphan-drug exclusivity
  • REMS program

Regulatory

Application
NDA215110
TE code
Approval date
Jun 10, 2021
Patents / exclusivity
16 patents, 3 exclusivities
TypeNumber / codeExpires
exclusivityPEDDec 10, 2028
exclusivityODE-372Jun 10, 2028
exclusivityI-967Jun 10, 2028
patent9321807*PEDDec 5, 2035
patentRE48923*PEDNov 8, 2035
patent9321807Jun 5, 2035
patentRE48923May 8, 2035
patent10286029*PEDSep 14, 2034
patent10286029Mar 14, 2034
patent8937150*PEDNov 18, 2032
patent8648037*PEDJul 19, 2032
patent8937150May 18, 2032

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of Glecaprevir and Pibrentasvir (Pellet)

LabelerStrengthFirst seenLast seen
AbbVie Inc.PIBRENTASVIR 20 mg/1; GLECAPREVIR 50 mg/1Aug 26, 2026Sep 2, 2026
AbbVie Inc.PIBRENTASVIR 50 mg/1; GLECAPREVIR 20 mg/1Jul 22, 2026Aug 19, 2026
AbbVie Inc.GLECAPREVIR 50 mg/1; PIBRENTASVIR 20 mg/1Jul 15, 2026Jul 15, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Mavyret — NDC 00074-2600-28," retrieved September 3, 2026, https://drugdashboards.com/drug/00074260028.

Free to cite with attribution — see how the data is put together.