DrugDashboards

Lotrel

amlodipine besylate and benazepril hydrochloride · AMLODIPINE BESYLATE 5 mg/1; BENAZEPRIL HYDROCHLORIDE 10 mg/1 · Capsule · Oral · Novartis Pharmaceuticals Corporation

NDC 00078-0405-05 · 100 CAPSULE in 1 BOTTLE · NDA · View full market →

The short version

11 companies supply this market — deep enough that no single failure threatens the supply. The price is up 22% over the past year, to $11.56 per unit. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$11.56per EAinvoice-surveyed acquisition cost · Nov 19, 2025
  • Part D plans paid (avg)$12.69per dosage unitgross, before rebates — matched by drug name · 2024
  • Part D point of sale (median)$11.40per unitnegotiated price across 2 plans — before rebates · Jul 1, 2024
  • Federal contracts pay (FSS)$7.65per unitSandoz, Inc. · Jan 1, 202666% of what pharmacies pay — a deeper discount than 81% of drugs with this benchmark
  • Medicaid generic ceiling (FUL)$0.1024per CAPweighted avg manufacturer price $0.0454 · Aug 1, 20261% of what pharmacies pay — a deeper discount than 95% of drugs with this benchmark
  • List price (WAC, as filed)$1,095.48per packageNovartis Pharmaceuticals Corporation · Jan 4, 2023

Medicare Part D

All Part D pricing →
ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$11.40per unit
middle half $11.40$11.40 · 2 plans · Jul 1, 2024
Est. net of rebates
$6.84–$8.55
brand drug — est. 25-40% rebate off the price at left
Coverage & restrictions
of plans cover it

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 3 quarters since 2024.

NADAC price per unit

$0$5.00$10.00$15.00Feb 2013Nov 2025$11.56
19 price points · per EA · last surveyed Invalid Date · dashed = manufacturer avg (WAMP)Source: CMS NADAC

Estimated fill cost

#30 count
$346.66
#90 count
$1039.98

Estimates: latest NADAC unit price × quantity. Pharmacy acquisition cost only — excludes dispensing fees, markup, and insurance terms.

Supply fragility

0Low risk

Nothing here is signaling trouble: several manufacturers, no current shortage, no recent serious recalls, stable pricing. In drug supply, boring is the good outcome.

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.2%chance of a new FDA shortage posting for amlodipine besylate and benazepril hydrochloride (oral solid) in the next 90 days

OAI inspection at a producing facility (24 months) · sole-source market · price up 2% YoY

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Regulatory

Application
NDA020364
TE code
Approval date
Mar 3, 1995
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of amlodipine besylate and benazepril hydrochloride (Capsule)

LabelerStrengthFirst seenLast seen
Bryant Ranch PrepackAMLODIPINE BESYLATE 5 mg/1; BENAZEPRIL HYDROCHLORIDE 20 mg/1Jul 15, 2026Sep 3, 2026
Lupin Pharmaceuticals, Inc.AMLODIPINE BESYLATE 10 mg/1; BENAZEPRIL HYDROCHLORIDE 40 mg/1Jul 15, 2026Sep 3, 2026
Lupin Pharmaceuticals, Inc.AMLODIPINE BESYLATE 5 mg/1; BENAZEPRIL HYDROCHLORIDE 20 mg/1Jul 15, 2026Sep 3, 2026
A-S Medication SolutionsAMLODIPINE BESYLATE 5 mg/1; BENAZEPRIL HYDROCHLORIDE 20 mg/1Jul 15, 2026Sep 2, 2026
A-S Medication SolutionsAMLODIPINE BESYLATE 10 mg/1; BENAZEPRIL HYDROCHLORIDE 40 mg/1Jul 15, 2026Sep 2, 2026
A-S Medication SolutionsAMLODIPINE BESYLATE 5 mg/1; BENAZEPRIL HYDROCHLORIDE 10 mg/1Jul 15, 2026Sep 2, 2026
A-S Medication SolutionsAMLODIPINE BESYLATE 5 mg/1; BENAZEPRIL HYDROCHLORIDE 40 mg/1Jul 15, 2026Sep 2, 2026
Amneal Pharmaceuticals NY LLCAMLODIPINE BESYLATE 5 mg/1; BENAZEPRIL HYDROCHLORIDE 20 mg/1Jul 15, 2026Sep 2, 2026
Amneal Pharmaceuticals NY LLCAMLODIPINE BESYLATE 2.5 mg/1; BENAZEPRIL HYDROCHLORIDE 10 mg/1Jul 15, 2026Sep 2, 2026
Amneal Pharmaceuticals NY LLCAMLODIPINE BESYLATE 10 mg/1; BENAZEPRIL HYDROCHLORIDE 20 mg/1Jul 15, 2026Sep 2, 2026
Amneal Pharmaceuticals NY LLCAMLODIPINE BESYLATE 5 mg/1; BENAZEPRIL HYDROCHLORIDE 10 mg/1Jul 15, 2026Sep 2, 2026
BluePoint LaboratoriesAMLODIPINE BESYLATE 5 mg/1; BENAZEPRIL HYDROCHLORIDE 40 mg/1Jul 15, 2026Sep 2, 2026
BluePoint LaboratoriesAMLODIPINE BESYLATE 10 mg/1; BENAZEPRIL HYDROCHLORIDE 20 mg/1Jul 15, 2026Sep 2, 2026
BluePoint LaboratoriesAMLODIPINE BESYLATE 10 mg/1; BENAZEPRIL HYDROCHLORIDE 40 mg/1Jul 15, 2026Sep 2, 2026
BluePoint LaboratoriesAMLODIPINE BESYLATE 2.5 mg/1; BENAZEPRIL HYDROCHLORIDE 10 mg/1Jul 15, 2026Sep 2, 2026
BluePoint LaboratoriesAMLODIPINE BESYLATE 5 mg/1; BENAZEPRIL HYDROCHLORIDE 10 mg/1Jul 15, 2026Sep 2, 2026
BluePoint LaboratoriesAMLODIPINE BESYLATE 5 mg/1; BENAZEPRIL HYDROCHLORIDE 20 mg/1Jul 15, 2026Sep 2, 2026
Bryant Ranch PrepackAMLODIPINE BESYLATE 10 mg/1; BENAZEPRIL HYDROCHLORIDE 40 mg/1Jul 15, 2026Sep 2, 2026
Bryant Ranch PrepackAMLODIPINE BESYLATE 5 mg/1; BENAZEPRIL HYDROCHLORIDE 10 mg/1Jul 15, 2026Sep 2, 2026
Bryant Ranch PrepackAMLODIPINE BESYLATE 5 mg/1; BENAZEPRIL HYDROCHLORIDE 40 mg/1Jul 15, 2026Sep 2, 2026
Bryant Ranch PrepackAMLODIPINE BESYLATE 10 mg/1; BENAZEPRIL HYDROCHLORIDE 20 mg/1Jul 15, 2026Sep 2, 2026
Dr.Reddy's Laboratories LimitedAMLODIPINE BESYLATE 5 mg/1; BENAZEPRIL HYDROCHLORIDE 10 mg/1Jul 15, 2026Sep 2, 2026
Dr.Reddy's Laboratories LimitedAMLODIPINE BESYLATE 10 mg/1; BENAZEPRIL HYDROCHLORIDE 40 mg/1Jul 15, 2026Sep 2, 2026
Dr.Reddy's Laboratories LimitedAMLODIPINE BESYLATE 10 mg/1; BENAZEPRIL HYDROCHLORIDE 20 mg/1Jul 15, 2026Sep 2, 2026
Dr.Reddy's Laboratories LimitedAMLODIPINE BESYLATE 2.5 mg/1; BENAZEPRIL HYDROCHLORIDE 10 mg/1Jul 15, 2026Sep 2, 2026
Dr.Reddy's Laboratories LimitedAMLODIPINE BESYLATE 5 mg/1; BENAZEPRIL HYDROCHLORIDE 40 mg/1Jul 15, 2026Sep 2, 2026
Dr.Reddy's Laboratories LimitedAMLODIPINE BESYLATE 5 mg/1; BENAZEPRIL HYDROCHLORIDE 20 mg/1Jul 15, 2026Sep 2, 2026
Lupin Pharmaceuticals, Inc.AMLODIPINE BESYLATE 5 mg/1; BENAZEPRIL HYDROCHLORIDE 10 mg/1Jul 15, 2026Sep 2, 2026
Lupin Pharmaceuticals, Inc.AMLODIPINE BESYLATE 2.5 mg/1; BENAZEPRIL HYDROCHLORIDE 10 mg/1Jul 15, 2026Sep 2, 2026
Northwind Health Company, LLCAMLODIPINE BESYLATE 10 mg/1; BENAZEPRIL HYDROCHLORIDE 20 mg/1Jul 15, 2026Sep 2, 2026
Northwind Health Company, LLCBENAZEPRIL HYDROCHLORIDE 20 mg/1; AMLODIPINE BESYLATE 5 mg/1Aug 26, 2026Sep 2, 2026
Novartis Pharmaceuticals CorporationAMLODIPINE BESYLATE 5 mg/1; BENAZEPRIL HYDROCHLORIDE 10 mg/1Jul 15, 2026Sep 2, 2026
PD-Rx Pharmaceuticals, Inc.AMLODIPINE BESYLATE 10 mg/1; BENAZEPRIL HYDROCHLORIDE 20 mg/1Jul 15, 2026Sep 2, 2026
PD-Rx Pharmaceuticals, Inc.AMLODIPINE BESYLATE 5 mg/1; BENAZEPRIL HYDROCHLORIDE 10 mg/1Jul 15, 2026Sep 2, 2026
Preferred Pharmaceuticals Inc.AMLODIPINE BESYLATE 10 mg/1; BENAZEPRIL HYDROCHLORIDE 20 mg/1Jul 15, 2026Sep 2, 2026
Remedyrepack Inc.AMLODIPINE BESYLATE 10 mg/1; BENAZEPRIL HYDROCHLORIDE 40 mg/1Jul 15, 2026Sep 2, 2026
Remedyrepack Inc.AMLODIPINE BESYLATE 5 mg/1; BENAZEPRIL HYDROCHLORIDE 40 mg/1Jul 15, 2026Sep 2, 2026
Remedyrepack Inc.AMLODIPINE BESYLATE 10 mg/1; BENAZEPRIL HYDROCHLORIDE 20 mg/1Jul 15, 2026Sep 2, 2026
Remedyrepack Inc.AMLODIPINE BESYLATE 5 mg/1; BENAZEPRIL HYDROCHLORIDE 10 mg/1Jul 15, 2026Sep 2, 2026
Remedyrepack Inc.AMLODIPINE BESYLATE 5 mg/1; BENAZEPRIL HYDROCHLORIDE 20 mg/1Jul 15, 2026Sep 2, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Lotrel — NDC 00078-0405-05," retrieved September 3, 2026, https://drugdashboards.com/drug/00078040505.

Free to cite with attribution — see how the data is put together.