DrugDashboards

good sense anti diarrheal anti gas

loperamide hydrochloride, simethicone · LOPERAMIDE HYDROCHLORIDE 2 mg/1; DIMETHICONE 125 mg/1 · Tablet · Oral · L. Perrigo Company

NDC 00113-0087-53 · 12 BLISTER PACK in 1 CARTON / 1 TABLET in 1 BLISTER PACK · ANDA · View full market →

The short version

20 companies supply this market — deep enough that no single failure threatens the supply. The price is up 8% over the past year, to $0.2867 per unit. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

Medicare Part D

No Medicare Part D plan in CMS's quarterly files lists this product. That usually means it is discontinued, a repackager's listing, or a product no plan has added to its formulary.

How Part D pricing works →

NADAC price per unit

$0$0.2$0.4Sep 2021Sep 2026$0.2867
57 price points · per EASource: CMS NADAC

Estimated fill cost

#30 count
$8.60
#90 count
$25.80

Estimates: latest NADAC unit price × quantity. Pharmacy acquisition cost only — excludes dispensing fees, markup, and insurance terms.

Supply fragility

0Low risk

Nothing here is signaling trouble: several manufacturers, no current shortage, no recent serious recalls, stable pricing. In drug supply, boring is the good outcome.

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for loperamide hydrochloride, simethicone (oral solid) in the next 90 days

sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Regulatory

Application
ANDA209837
TE code
Approval date
Sep 5, 2018
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of loperamide hydrochloride, simethicone (Tablet)

LabelerStrengthFirst seenLast seen
L. Perrigo CompanyLOPERAMIDE HYDROCHLORIDE 2 mg/1; DIMETHICONE 125 mg/1Aug 26, 2026Sep 3, 2026
Amazon.com Services LLCLOPERAMIDE HYDROCHLORIDE 2 mg/1; DIMETHICONE 125 mg/1Aug 26, 2026Sep 2, 2026
American Sales CompanyLOPERAMIDE HYDROCHLORIDE 2 mg/1; DIMETHICONE 125 mg/1Aug 26, 2026Sep 2, 2026
Amerisource BergenLOPERAMIDE HYDROCHLORIDE 2 mg/1; DIMETHICONE 125 mg/1Aug 26, 2026Sep 2, 2026
CVS PharmacyLOPERAMIDE HYDROCHLORIDE 2 mg/1; DIMETHICONE 125 mg/1Aug 26, 2026Sep 2, 2026
Discount Drug Mart, IncLOPERAMIDE HYDROCHLORIDE 2 mg/1; DIMETHICONE 125 mg/1Aug 26, 2026Sep 2, 2026
Dolgencorp, LLCLOPERAMIDE HYDROCHLORIDE 2 mg/1; DIMETHICONE 125 mg/1Aug 26, 2026Sep 2, 2026
Guardian Drug CompanyLOPERAMIDE HYDROCHLORIDE 2 mg/1; DIMETHICONE 125 mg/1Aug 26, 2026Sep 2, 2026
H E BLOPERAMIDE HYDROCHLORIDE 2 mg/1; DIMETHICONE 125 mg/1Aug 26, 2026Sep 2, 2026
Harris Teeter, LLCLOPERAMIDE HYDROCHLORIDE 2 mg/1; DIMETHICONE 125 mg/1Aug 26, 2026Sep 2, 2026
HyVee IncLOPERAMIDE HYDROCHLORIDE 2 mg/1; DIMETHICONE 125 mg/1Aug 26, 2026Sep 2, 2026
Kroger CompanyLOPERAMIDE HYDROCHLORIDE 2 mg/1; DIMETHICONE 125 mg/1Aug 26, 2026Sep 2, 2026
Meijer Distribution IncLOPERAMIDE HYDROCHLORIDE 2 mg/1; DIMETHICONE 125 mg/1Aug 26, 2026Sep 2, 2026
Rite Aid CorporationLOPERAMIDE HYDROCHLORIDE 2 mg/1; DIMETHICONE 125 mg/1Aug 26, 2026Sep 2, 2026
SafewayLOPERAMIDE HYDROCHLORIDE 2 mg/1; DIMETHICONE 125 mg/1Aug 26, 2026Sep 2, 2026
Strategic Sourcing Services LLCLOPERAMIDE HYDROCHLORIDE 2 mg/1; DIMETHICONE 125 mg/1Aug 26, 2026Sep 2, 2026
Target CorporationLOPERAMIDE HYDROCHLORIDE 2 mg/1; DIMETHICONE 125 mg/1Aug 26, 2026Sep 2, 2026
United Natural Foods, Inc. dba UNFILOPERAMIDE HYDROCHLORIDE 2 mg/1; DIMETHICONE 125 mg/1Aug 26, 2026Sep 2, 2026
Walgreen CompanyLOPERAMIDE HYDROCHLORIDE 2 mg/1; DIMETHICONE 125 mg/1Aug 26, 2026Sep 2, 2026
Walmart Inc.LOPERAMIDE HYDROCHLORIDE 2 mg/1; DIMETHICONE 125 mg/1Aug 26, 2026Sep 2, 2026
L. Perrigo CompanyLOPERAMIDE HYDROCHLORIDE 125 mg/1; DIMETHICONE 2 mg/1Jul 22, 2026Aug 21, 2026
Amazon.com Services LLCLOPERAMIDE HYDROCHLORIDE 125 mg/1; DIMETHICONE 2 mg/1Jul 22, 2026Aug 19, 2026
American Sales CompanyLOPERAMIDE HYDROCHLORIDE 125 mg/1; DIMETHICONE 2 mg/1Jul 22, 2026Aug 19, 2026
Amerisource BergenLOPERAMIDE HYDROCHLORIDE 125 mg/1; DIMETHICONE 2 mg/1Jul 22, 2026Aug 19, 2026
CVS PharmacyLOPERAMIDE HYDROCHLORIDE 125 mg/1; DIMETHICONE 2 mg/1Jul 22, 2026Aug 19, 2026
Discount Drug Mart, IncLOPERAMIDE HYDROCHLORIDE 125 mg/1; DIMETHICONE 2 mg/1Jul 22, 2026Aug 19, 2026
Dolgencorp, LLCLOPERAMIDE HYDROCHLORIDE 125 mg/1; DIMETHICONE 2 mg/1Jul 22, 2026Aug 19, 2026
Guardian Drug CompanyLOPERAMIDE HYDROCHLORIDE 125 mg/1; DIMETHICONE 2 mg/1Jul 22, 2026Aug 19, 2026
H E BLOPERAMIDE HYDROCHLORIDE 125 mg/1; DIMETHICONE 2 mg/1Jul 22, 2026Aug 19, 2026
Harris Teeter, LLCLOPERAMIDE HYDROCHLORIDE 125 mg/1; DIMETHICONE 2 mg/1Jul 22, 2026Aug 19, 2026
HyVee IncLOPERAMIDE HYDROCHLORIDE 125 mg/1; DIMETHICONE 2 mg/1Jul 22, 2026Aug 19, 2026
Kroger CompanyLOPERAMIDE HYDROCHLORIDE 125 mg/1; DIMETHICONE 2 mg/1Jul 22, 2026Aug 19, 2026
Meijer Distribution IncLOPERAMIDE HYDROCHLORIDE 125 mg/1; DIMETHICONE 2 mg/1Jul 22, 2026Aug 19, 2026
Rite Aid CorporationLOPERAMIDE HYDROCHLORIDE 125 mg/1; DIMETHICONE 2 mg/1Jul 22, 2026Aug 19, 2026
SafewayLOPERAMIDE HYDROCHLORIDE 125 mg/1; DIMETHICONE 2 mg/1Jul 22, 2026Aug 19, 2026
Strategic Sourcing Services LLCLOPERAMIDE HYDROCHLORIDE 125 mg/1; DIMETHICONE 2 mg/1Jul 22, 2026Aug 19, 2026
Target CorporationLOPERAMIDE HYDROCHLORIDE 125 mg/1; DIMETHICONE 2 mg/1Jul 22, 2026Aug 19, 2026
United Natural Foods, Inc. dba UNFILOPERAMIDE HYDROCHLORIDE 125 mg/1; DIMETHICONE 2 mg/1Jul 22, 2026Aug 19, 2026
Walgreen CompanyLOPERAMIDE HYDROCHLORIDE 125 mg/1; DIMETHICONE 2 mg/1Jul 22, 2026Aug 19, 2026
Walmart Inc.LOPERAMIDE HYDROCHLORIDE 125 mg/1; DIMETHICONE 2 mg/1Jul 22, 2026Aug 19, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "good sense anti diarrheal anti gas — NDC 00113-0087-53," retrieved September 3, 2026, https://drugdashboards.com/drug/00113008753.

Free to cite with attribution — see how the data is put together.