The short version
4 companies supply this market — a reasonable cushion if one runs into trouble.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
Guaifenesin and Codeine Phosphate
Guaifenesin and Codeine Phosphate · GUAIFENESIN 200 mg/10mL; CODEINE PHOSPHATE 20 mg/10mL · Solution · Oral · PAI Holdings, LLC
NDC 00121-1550-00 · 10 TRAY in 1 CASE / 10 CUP, UNIT-DOSE in 1 TRAY / 10 mL in 1 CUP, UNIT-DOSE · OTC MONOGRAPH DRUG · View full market →
Medicare Part D
Medicare Part D does not cover over-the-counter drugs — by law it pays only for products requiring a prescription.
How Part D pricing works →NADAC price per unit
No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.
Medicaid spend (2025)
$97
24 prescriptions paid by Medicaid nationally · all Medicaid spend →
Supply fragility
Not scored — fragility is computed for NADAC-priced NDCs.
90-day shortage risk (model v2)
0.1%chance of a new FDA shortage posting for guaifenesin and codeine phosphate (other) in the next 90 days
sole-source market · price up 5% YoY
For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.
Backtested statistical model over the whole market, not this package alone. Model details →
Regulatory
- Application
- M012
- TE code
- —
- Approval date
- —
- Patents / exclusivity
- None on file
Shortage history
No FDA shortage reports for this drug or its presentations.
Recalls (this NDC)
- Class III · TerminatedJan 7, 2025PAI Holdings, LLC. dba Pharmaceutical Associates Inc — Superpotent; sodium benzoate preservative
Manufacturers of Guaifenesin and Codeine Phosphate (Solution)
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| A-S Medication Solutions | GUAIFENESIN 100 mg/5mL; CODEINE PHOSPHATE 10 mg/5mL | Aug 26, 2026 | Sep 2, 2026 |
| Cardinal Health 107, LLC | CODEINE PHOSPHATE 10 mg/5mL; GUAIFENESIN 100 mg/5mL | Jul 15, 2026 | Sep 2, 2026 |
| PAI Holdings, LLC | GUAIFENESIN 200 mg/10mL; CODEINE PHOSPHATE 20 mg/10mL | Aug 26, 2026 | Sep 2, 2026 |
| PAI Holdings, LLC | GUAIFENESIN 100 mg/5mL; CODEINE PHOSPHATE 10 mg/5mL | Aug 26, 2026 | Sep 2, 2026 |
| Preferred Pharmaceuticals Inc. | GUAIFENESIN 100 mg/5mL; CODEINE PHOSPHATE 10 mg/5mL | Aug 26, 2026 | Sep 2, 2026 |
| PAI Holdings, LLC | GUAIFENESIN 10 mg/5mL; CODEINE PHOSPHATE 100 mg/5mL | Jul 22, 2026 | Aug 22, 2026 |
| A-S Medication Solutions | GUAIFENESIN 10 mg/5mL; CODEINE PHOSPHATE 100 mg/5mL | Jul 22, 2026 | Aug 19, 2026 |
| PAI Holdings, LLC | GUAIFENESIN 20 mg/10mL; CODEINE PHOSPHATE 200 mg/10mL | Jul 22, 2026 | Aug 19, 2026 |
| Preferred Pharmaceuticals Inc. | GUAIFENESIN 10 mg/5mL; CODEINE PHOSPHATE 100 mg/5mL | Jul 22, 2026 | Aug 19, 2026 |
| PAI Holdings, LLC | CODEINE PHOSPHATE 10 mg/5mL; GUAIFENESIN 100 mg/5mL | Jul 15, 2026 | Jul 19, 2026 |
| A-S Medication Solutions | CODEINE PHOSPHATE 10 mg/5mL; GUAIFENESIN 100 mg/5mL | Jul 15, 2026 | Jul 15, 2026 |
| PAI Holdings, LLC | CODEINE PHOSPHATE 20 mg/10mL; GUAIFENESIN 200 mg/10mL | Jul 15, 2026 | Jul 15, 2026 |
| Preferred Pharmaceuticals Inc. | CODEINE PHOSPHATE 10 mg/5mL; GUAIFENESIN 100 mg/5mL | Jul 15, 2026 | Jul 15, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
Cite this page
DrugDashboards, "Guaifenesin and Codeine Phosphate — NDC 00121-1550-00," retrieved September 3, 2026, https://drugdashboards.com/drug/00121155000.
Free to cite with attribution — see how the data is put together.