The short version
Only one company currently supplies this market — there is no backup if it stumbles.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
Combogesic Iv
acetaminophen and ibuprofen injection · ACETAMINOPHEN 1000 mg/100mL; IBUPROFEN 300 mg/100mL · Injection · Intravenous · Hikma Pharmaceuticals USA Inc.
NDC 00143-9150-10 · 10 VIAL in 1 CARTON / 100 mL in 1 VIAL · NDA · View full market →
Medicare Part D
No Medicare Part D plan in CMS's quarterly files lists this product. That usually means it is discontinued, a repackager's listing, or a product no plan has added to its formulary.
How Part D pricing works →NADAC price per unit
No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.
Estimated fill cost
WAC per package, as filed
$230.00
Reported to Texas DSHS · 2026 annual filing · Hikma Pharmaceuticals USA Inc.
Manufacturer list price as filed — not what pharmacies actually pay after discounts.
Medicare Part B (ASP)
Payment limit per 10 MG/3MG
$0.092
HCPCS J0138 · Jul 1, 2026 quarter · typically ASP + 6%
Supply fragility
Not scored — fragility is computed for NADAC-priced NDCs.
Is this a "specialty" drug?
There's no legal definition — it meets 2 of 6 public criteria. Why that matters →
- Part D specialty tier
- Costs ≥ $950/fill
- Biologic (BLA)
- Injectable / infused
- Orphan-drug exclusivity
- REMS program · Opioid Analgesic REMS Shared System REMS
Regulatory
- Application
- NDA215320
- TE code
- —
- Approval date
- Oct 17, 2023
- Patents / exclusivity
- 6 patents, 1 exclusivities
| Type | Number / code | Expires |
|---|---|---|
| exclusivity | NP | Oct 17, 2026 |
| patent | 11213498 | Jan 14, 2036 |
| patent | 11389416 | Jul 17, 2035 |
| patent | 12083087 | Jul 17, 2035 |
| patent | 11896567 | Oct 26, 2031 |
| patent | 11446266 | Oct 26, 2031 |
| patent | 12220392 | Oct 26, 2031 |
Shortage history
No FDA shortage reports for this drug or its presentations.
Recalls (this NDC)
No enforcement reports list this package NDC.
Manufacturers of acetaminophen and ibuprofen injection (Injection)
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| Hikma Pharmaceuticals USA Inc. | ACETAMINOPHEN 1000 mg/100mL; IBUPROFEN 300 mg/100mL | Jul 15, 2026 | Sep 2, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
Cite this page
DrugDashboards, "Combogesic Iv — NDC 00143-9150-10," retrieved September 3, 2026, https://drugdashboards.com/drug/00143915010.
Free to cite with attribution — see how the data is put together.