DrugDashboards

Advair Hfa

fluticasone propionate and salmeterol xinafoate · FLUTICASONE PROPIONATE 45 ug/1; SALMETEROL XINAFOATE 21 ug/1 · Aerosol, Metered · Respiratory (Inhalation) · GlaxoSmithKline LLC

NDC 00173-0715-20 · 1 INHALER in 1 CARTON / 120 AEROSOL, METERED in 1 INHALER · NDA · View full market →

The short version

Just 3 companies supply this market — thin enough that a single exit would be felt immediately. The brand price has held steady around $19.97 per gram over the past year. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$19.97per GMinvoice-surveyed acquisition cost · Aug 19, 2026
  • Part D plans paid (avg)$28.71per dosage unitgross, before rebates — matched by drug name · 2024
  • Part D point of sale (median)$19.94per unitnegotiated price across 3,661 plans — before rebates · Apr 1, 2026
  • Federal ceiling (Big4)$179.54per package of 12GMGlaxoSmithKline · Jan 1, 2026

Medicare Part D

All Part D pricing →
ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$19.94per unit
middle half $19.51$20.15 · 3,661 plans · Apr 1, 2026
Est. net of rebates
$11.96–$14.95
brand drug — est. 25-40% rebate off the price at left
Coverage & restrictions
67%of plans cover it
tier 3 · prior auth 0% · step therapy 0% · qty limit 95%

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.

NADAC price per unit

$0$10.00$20.00$30.00Jul 2013Sep 2026$19.97
49 price points · per GMSource: CMS NADAC

Estimated fill cost

WAC per package, as filed
$250.80
Reported to Texas DSHS · 2026 annual filing · GlaxoSmithKline LLC

Manufacturer list price as filed — not what pharmacies actually pay after discounts.

Medicaid spend (2025)

$15.8M
62,533 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

10Low risk

Some pressure is visible, but not much — here’s everything the score found to count.

  • 3 active manufacturers+10

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for fluticasone propionate and salmeterol xinafoate (other) in the next 90 days

sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Regulatory

Application
NDA021254
TE code
Approval date
Jun 8, 2006
Patents / exclusivity
None on file

Shortage history

  • Planned discontinuation Advair HFA, Aerosol, Metered, 115 ug; 21 ug (NDC 0173-0716-22)Jul 27, 2026
  • Planned discontinuation Advair HFA, Aerosol, Metered, 230 ug; 21 ug (NDC 0173-0717-22)Jul 27, 2026
  • Planned discontinuation Advair HFA, Aerosol, Metered, 45 ug; 21 ug (NDC 0173-0715-22)Jul 27, 2026

Recalls (this NDC)

  • Class III · TerminatedOct 24, 2012
    GlaxoSmithKline, LLC.Product Lacks Stability: These lots are being recalled due to the failure to meet the particle size distribution specification.
  • Class III · TerminatedOct 24, 2012
    GlaxoSmithKline, LLC.Product Lacks Stability: These lots are being recalled due to the failure to meet the particle size distribution specification.

Manufacturers of fluticasone propionate and salmeterol xinafoate (Aerosol, Metered)

LabelerStrengthFirst seenLast seen
GlaxoSmithKline LLCFLUTICASONE PROPIONATE 230 ug/1; SALMETEROL XINAFOATE 21 ug/1Jul 15, 2026Sep 2, 2026
GlaxoSmithKline LLCFLUTICASONE PROPIONATE 115 ug/1; SALMETEROL XINAFOATE 21 ug/1Jul 15, 2026Sep 2, 2026
GlaxoSmithKline LLCFLUTICASONE PROPIONATE 45 ug/1; SALMETEROL XINAFOATE 21 ug/1Jul 15, 2026Sep 2, 2026
Prasco LaboratoriesFLUTICASONE PROPIONATE 230 ug/1; SALMETEROL XINAFOATE 21 ug/1Jul 15, 2026Sep 2, 2026
Prasco LaboratoriesFLUTICASONE PROPIONATE 45 ug/1; SALMETEROL XINAFOATE 21 ug/1Jul 15, 2026Sep 2, 2026
Prasco LaboratoriesFLUTICASONE PROPIONATE 115 ug/1; SALMETEROL XINAFOATE 21 ug/1Jul 15, 2026Sep 2, 2026
A-S Medication SolutionsFLUTICASONE PROPIONATE 115 ug/1; SALMETEROL XINAFOATE 21 ug/1Jul 15, 2026Aug 28, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Advair Hfa — NDC 00173-0715-20," retrieved September 3, 2026, https://drugdashboards.com/drug/00173071520.

Free to cite with attribution — see how the data is put together.