DrugDashboards

Nexium

Esomeprazole magnesium · ESOMEPRAZOLE MAGNESIUM TRIHYDRATE 40 mg/1 · Granule, Delayed Release · Oral · AstraZeneca Pharmaceuticals LP

NDC 00186-4040-01 · 30 GRANULE, DELAYED RELEASE in 1 CARTON · NDA · View full market →

The short version

5 companies supply this market — a reasonable cushion if one runs into trouble. The brand price has held steady around $9.13 per unit over the past year. Generic versions run $4.51 per unit2× cheaper. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$9.13per EAinvoice-surveyed acquisition cost · Aug 19, 2026
  • Part D plans paid (avg)$8.85per dosage unitgross, before rebates — matched by drug name · 2024
  • Part D point of sale (median)$9.37per unitnegotiated price across 2 plans — before rebates · Apr 1, 2026
  • Federal ceiling (Big4)$214.77per package of 30PKTASTRAZENECA PHARMACEUTICALS LP · Jan 1, 2026

Medicare Part D

All Part D pricing →
ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$9.37per unit
middle half $9.37$9.37 · 2 plans · Apr 1, 2026
Est. net of rebates
$5.62–$7.03
brand drug — est. 25-40% rebate off the price at left
Coverage & restrictions
0%of plans cover it
tier 1 · prior auth 0% · step therapy 100% · qty limit 100%

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.

NADAC price per unit

$0$5.00$10.00Nov 2013Sep 2026$9.13
48 price points · per EASource: CMS NADAC

Estimated fill cost

WAC per package, as filed
$287.28
Reported to Texas DSHS · 2026 annual filing · AstraZeneca

Manufacturer list price as filed — not what pharmacies actually pay after discounts.

Medicaid spend (2025)

$6.1M
18,180 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

5Low risk

Some pressure is visible, but not much — here’s everything the score found to count.

  • 5 active manufacturers+5

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for esomeprazole magnesium (other) in the next 90 days

sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Regulatory

Application
NDA021957
TE code
AB
Approval date
Oct 20, 2006
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

  • Class III · TerminatedJul 2, 2012
    ASTRA ZENECA LpAdulterated Presence of Foreign Tablets/Capsules: Some bottles may contain a small number of Nexium 20 mg capsules intended for the Japanese market in addtion to Nexium 40 mg capsules.

Manufacturers of Esomeprazole magnesium (Granule, Delayed Release)

LabelerStrengthFirst seenLast seen
AstraZeneca Pharmaceuticals LPESOMEPRAZOLE MAGNESIUM TRIHYDRATE 10 mg/1Jul 15, 2026Sep 2, 2026
AstraZeneca Pharmaceuticals LPESOMEPRAZOLE MAGNESIUM TRIHYDRATE 5 mg/1Jul 15, 2026Sep 2, 2026
AstraZeneca Pharmaceuticals LPESOMEPRAZOLE MAGNESIUM TRIHYDRATE 40 mg/1Jul 15, 2026Sep 2, 2026
AstraZeneca Pharmaceuticals LPESOMEPRAZOLE MAGNESIUM TRIHYDRATE 20 mg/1Jul 15, 2026Sep 2, 2026
AstraZeneca Pharmaceuticals LPESOMEPRAZOLE MAGNESIUM TRIHYDRATE 2.5 mg/1Jul 15, 2026Sep 2, 2026
Aurobindo Pharma LimitedESOMEPRAZOLE MAGNESIUM TRIHYDRATE 5 mg/1Jul 15, 2026Sep 2, 2026
Aurobindo Pharma LimitedESOMEPRAZOLE MAGNESIUM TRIHYDRATE 10 mg/1Jul 15, 2026Sep 2, 2026
Aurobindo Pharma LimitedESOMEPRAZOLE MAGNESIUM TRIHYDRATE 20 mg/1Jul 15, 2026Sep 2, 2026
Aurobindo Pharma LimitedESOMEPRAZOLE MAGNESIUM TRIHYDRATE 40 mg/1Jul 15, 2026Sep 2, 2026
Torrent Pharmaceuticals LimitedESOMEPRAZOLE MAGNESIUM 20 mg/1Jul 15, 2026Sep 2, 2026
Torrent Pharmaceuticals LimitedESOMEPRAZOLE MAGNESIUM 10 mg/1Jul 15, 2026Sep 2, 2026
Torrent Pharmaceuticals LimitedESOMEPRAZOLE MAGNESIUM 5 mg/1Jul 15, 2026Sep 2, 2026
Torrent Pharmaceuticals LimitedESOMEPRAZOLE MAGNESIUM 40 mg/1Jul 15, 2026Sep 2, 2026
Torrent Pharmaceuticals LimitedESOMEPRAZOLE MAGNESIUM 2.5 mg/1Jul 15, 2026Sep 2, 2026
Zydus Lifesciences LimitedESOMEPRAZOLE MAGNESIUM DIHYDRATE 20 mg/1Jul 15, 2026Sep 2, 2026
Zydus Lifesciences LimitedESOMEPRAZOLE MAGNESIUM DIHYDRATE 40 mg/1Jul 15, 2026Sep 2, 2026
Zydus Pharmaceuticals USA Inc.ESOMEPRAZOLE MAGNESIUM DIHYDRATE 40 mg/1Jul 15, 2026Sep 2, 2026
Zydus Pharmaceuticals USA Inc.ESOMEPRAZOLE MAGNESIUM DIHYDRATE 20 mg/1Jul 15, 2026Sep 2, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Nexium — NDC 00186-4040-01," retrieved September 3, 2026, https://drugdashboards.com/drug/00186404001.

Free to cite with attribution — see how the data is put together.