DrugDashboards

TrophAmine

ISOLEUCINE, LEUCINE, LYSINE ACETATE, METHIONINE, PHENYLALANINE, THREONINE, TRYPTOPHAN, VALINE, CYSTEINE HYDROCHLORIDE, HISTIDINE, TYROSINE, N-ACETYL-TYROSINE, ALANINE, ARGININE, PROLINE, SERINE, GLYCINE, ASPARTIC ACID, GLUTAMIC ACID, and TAURINE · ISOLEUCINE .82 g/100mL; LEUCINE 1.4 g/100mL; LYSINE ACETATE 1.2 g/100mL; METHIONINE .34 g/100mL; PHENYLALANINE .48 g/100mL; THREONINE .42 g/100mL; TRYPTOPHAN .2 g/100mL; VALINE .78 g/100mL; CYSTEINE HYDROCHLORIDE .024 g/100mL; HISTIDINE .48 g/100mL; TYROSINE .044 g/100mL; ACETYL L-TYROSINE .24 g/100mL; ALANINE .54 g/100mL; ARGININE 1.2 g/100mL; PROLINE .68 g/100mL; SERINE .38 g/100mL; GLYCINE .36 g/100mL; ASPARTIC ACID .32 g/100mL; GLUTAMIC ACID .5 g/100mL; TAURINE .025 g/100mL · Solution · Intravenous · B. Braun Medical Inc.

NDC 00264-1933-10 · 12 CONTAINER in 1 CASE / 500 mL in 1 CONTAINER · NDA · View full market →

The short version

Only one company currently supplies this market — there is no backup if it stumbles. It is in shortage right now.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

Medicare Part D

All Part D pricing →
ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of saleⓘ
$0.0955per unit
middle half $0.0934–$0.1097 · 4,965 plans · Apr 1, 2026
Est. net of rebatesⓘ
$0.0573–$0.0716
brand drug — est. 25-40% rebate off the price at left
Coverage & restrictions
90%of plans cover it
tier 4 · prior auth 97% · step therapy 0% · qty limit 0%

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.

NADAC price per unit

No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.

Estimated fill cost

WAC per package, as filed
$44.65
Reported to Texas DSHS · 2026 annual filing · B. Braun Medical Inc.

Manufacturer list price as filed — not what pharmacies actually pay after discounts.

Medicaid spend (2025)

$4.1M
5,857 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

Not scored — fragility is computed for NADAC-priced NDCs.

Is this a "specialty" drug?

There's no legal definition — it meets 1 of 6 public criteria. Why that matters →

  • Part D specialty tier · median tier 4 across plans
  • Costs ≥ $950/fill
  • Biologic (BLA)
  • Injectable / infused
  • Orphan-drug exclusivity
  • REMS program

Regulatory

Application
NDA019018
TE code
—
Approval date
Jul 20, 1984
Patents / exclusivity
None on file

Shortage history

  • In shortage now — TrophAmine 10%, Injection, 0.1 (NDC 0264-1933-10)Dec 8, 2020
    month 69 — 6× the typical 12-month other shortage

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of ISOLEUCINE, LEUCINE, LYSINE ACETATE, METHIONINE, PHENYLALANINE, THREONINE, TRYPTOPHAN, VALINE, CYSTEINE HYDROCHLORIDE, HISTIDINE, TYROSINE, N-ACETYL-TYROSINE, ALANINE, ARGININE, PROLINE, SERINE, GLYCINE, ASPARTIC ACID, GLUTAMIC ACID, and TAURINE (Solution)

LabelerStrengthFirst seenLast seen
B. Braun Medical Inc.ISOLEUCINE .82 g/100mL; LEUCINE 1.4 g/100mL; LYSINE ACETATE 1.2 g/100mL; METHIONINE .34 g/100mL; PHENYLALANINE .48 g/100mL; THREONINE .42 g/100mL; TRYPTOPHAN .2 g/100mL; VALINE .78 g/100mL; CYSTEINE HYDROCHLORIDE .024 g/100mL; HISTIDINE .48 g/100mL; TYROSINE .044 g/100mL; ACETYL L-TYROSINE .24 g/100mL; ALANINE .54 g/100mL; ARGININE 1.2 g/100mL; PROLINE .68 g/100mL; SERINE .38 g/100mL; GLYCINE .36 g/100mL; ASPARTIC ACID .32 g/100mL; GLUTAMIC ACID .5 g/100mL; TAURINE .025 g/100mLAug 26, 2026Sep 2, 2026
B. Braun Medical Inc.ISOLEUCINE .24 g/100mL; LEUCINE .54 g/100mL; LYSINE ACETATE 1.2 g/100mL; METHIONINE .32 g/100mL; PHENYLALANINE .024 g/100mL; THREONINE .5 g/100mL; TRYPTOPHAN .36 g/100mL; VALINE .48 g/100mL; CYSTEINE HYDROCHLORIDE .82 g/100mL; HISTIDINE 1.4 g/100mL; TYROSINE 1.2 g/100mL; ACETYL L-TYROSINE .34 g/100mL; ALANINE .48 g/100mL; ARGININE .68 g/100mL; PROLINE .38 g/100mL; SERINE .025 g/100mL; GLYCINE .42 g/100mL; ASPARTIC ACID .2 g/100mL; GLUTAMIC ACID .044 g/100mL; TAURINE .78 g/100mLJul 22, 2026Aug 19, 2026
B. Braun Medical Inc.ACETYL L-TYROSINE .24 g/100mL; ALANINE .54 g/100mL; ARGININE 1.2 g/100mL; ASPARTIC ACID .32 g/100mL; CYSTEINE HYDROCHLORIDE .024 g/100mL; GLUTAMIC ACID .5 g/100mL; GLYCINE .36 g/100mL; HISTIDINE .48 g/100mL; ISOLEUCINE .82 g/100mL; LEUCINE 1.4 g/100mL; LYSINE ACETATE 1.2 g/100mL; METHIONINE .34 g/100mL; PHENYLALANINE .48 g/100mL; PROLINE .68 g/100mL; SERINE .38 g/100mL; TAURINE .025 g/100mL; THREONINE .42 g/100mL; TRYPTOPHAN .2 g/100mL; TYROSINE .044 g/100mL; VALINE .78 g/100mLJul 15, 2026Jul 15, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "TrophAmine — NDC 00264-1933-10," retrieved September 3, 2026, https://drugdashboards.com/drug/00264193310.

Free to cite with attribution — see how the data is put together.