The short version
Only one company currently supplies this market — there is no backup if it stumbles.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
Alka-Seltzer Extra Strength Pain Relief
Anhydrous Citric Acid, Aspirin · CAFFEINE 65 mg/1; ASPIRIN 500 mg/1 · Tablet, Effervescent · Oral · Bayer HealthCare LLC.
NDC 00280-8260-20 · 10 POUCH in 1 CARTON / 2 TABLET, EFFERVESCENT in 1 POUCH · OTC MONOGRAPH DRUG · View full market →
Medicare Part D
Medicare Part D does not cover over-the-counter drugs — by law it pays only for products requiring a prescription.
How Part D pricing works →NADAC price per unit
No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.
Supply fragility
Not scored — fragility is computed for NADAC-priced NDCs.
Regulatory
- Application
- M013
- TE code
- —
- Approval date
- —
- Patents / exclusivity
- None on file
Shortage history
No FDA shortage reports for this drug or its presentations.
Recalls (this NDC)
No enforcement reports list this package NDC.
Manufacturers of Anhydrous Citric Acid, Aspirin (Tablet, Effervescent)
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| Bayer HealthCare LLC. | CAFFEINE 65 mg/1; ASPIRIN 500 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Bayer HealthCare LLC. | CAFFEINE 500 mg/1; ASPIRIN 65 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Bayer HealthCare LLC. | ASPIRIN 500 mg/1; CAFFEINE 65 mg/1 | Jul 15, 2026 | Jul 15, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
Cite this page
DrugDashboards, "Alka-Seltzer Extra Strength Pain Relief — NDC 00280-8260-20," retrieved September 3, 2026, https://drugdashboards.com/drug/00280826020.
Free to cite with attribution — see how the data is put together.