The short version
Just 2 companies supply this market — thin enough that a single exit would be felt immediately.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
ALKA SELTZER COLD Cold and Cough Maximum Strength Fast Dissolve
aspirin, chlorpheniramine maleate, dextromethorphan hydrobromide, phenylephrine bitartrate · DEXTROMETHORPHAN HYDROBROMIDE 10 mg/1; ASPIRIN 325 mg/1; CHLORPHENIRAMINE MALEATE 2 mg/1; PHENYLEPHRINE BITARTRATE 7.8 mg/1 · Tablet, Effervescent · Oral · Bayer Healthcare LLC.
NDC 00280-8267-16 · 8 POUCH in 1 CARTON / 2 TABLET, EFFERVESCENT in 1 POUCH · OTC MONOGRAPH DRUG · View full market →
Medicare Part D
Medicare Part D does not cover over-the-counter drugs — by law it pays only for products requiring a prescription.
How Part D pricing works →NADAC price per unit
No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.
Supply fragility
Not scored — fragility is computed for NADAC-priced NDCs.
Is this a "specialty" drug?
There's no legal definition — it meets 1 of 6 public criteria. Why that matters →
- Part D specialty tier
- Costs ≥ $950/fill
- Biologic (BLA)
- Injectable / infused
- Orphan-drug exclusivity
- REMS program · Opioid Analgesic REMS Shared System REMS
Regulatory
- Application
- M012
- TE code
- —
- Approval date
- —
- Patents / exclusivity
- None on file
Shortage history
No FDA shortage reports for this drug or its presentations.
Recalls (this NDC)
No enforcement reports list this package NDC.
Manufacturers of aspirin, chlorpheniramine maleate, dextromethorphan hydrobromide, phenylephrine bitartrate (Tablet, Effervescent)
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| Bayer Healthcare LLC. | DEXTROMETHORPHAN HYDROBROMIDE 10 mg/1; ASPIRIN 325 mg/1; CHLORPHENIRAMINE MALEATE 2 mg/1; PHENYLEPHRINE BITARTRATE 7.8 mg/1 | Aug 26, 2026 | Sep 3, 2026 |
| Bayer HealthCare LLC. | ASPIRIN 325 mg/1; CHLORPHENIRAMINE MALEATE 2 mg/1; DEXTROMETHORPHAN HYDROBROMIDE 10 mg/1; PHENYLEPHRINE BITARTRATE 7.8 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| Bayer Healthcare LLC. | DEXTROMETHORPHAN HYDROBROMIDE 325 mg/1; ASPIRIN 2 mg/1; CHLORPHENIRAMINE MALEATE 10 mg/1; PHENYLEPHRINE BITARTRATE 7.8 mg/1 | Jul 22, 2026 | Aug 22, 2026 |
| Bayer Healthcare LLC. | ASPIRIN 325 mg/1; CHLORPHENIRAMINE MALEATE 2 mg/1; DEXTROMETHORPHAN HYDROBROMIDE 10 mg/1; PHENYLEPHRINE BITARTRATE 7.8 mg/1 | Jul 15, 2026 | Jul 19, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
Cite this page
DrugDashboards, "ALKA SELTZER COLD Cold and Cough Maximum Strength Fast Dissolve — NDC 00280-8267-16," retrieved September 3, 2026, https://drugdashboards.com/drug/00280826716.
Free to cite with attribution — see how the data is put together.