DrugDashboards

Differin

adapalene · ADAPALENE 3 mg/g · Gel · Topical · Galderma Laboratories, L.P.

NDC 00299-5918-25 · 1 BOTTLE, PUMP in 1 CARTON / 45 g in 1 BOTTLE, PUMP · NDA · View full market →

The short version

31 companies supply this market — deep enough that no single failure threatens the supply. The price has held steady around $11.63 per unit over the past year.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Part D plans paid (avg)$9.03per dosage unitgross, before rebates — matched by drug name · 2024
  • Part D point of sale (median)$11.93per unitnegotiated price across 2 plans — before rebates · Jul 1, 2024
  • Medicaid generic ceiling (FUL)$0.7588per GMweighted avg manufacturer price $0.2366 · Jul 1, 2026

Medicare Part D

All Part D pricing →
ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$11.93per unit
middle half $11.93$11.93 · 2 plans · Jul 1, 2024
Est. net of rebates
$7.16–$8.95
brand drug — est. 25-40% rebate off the price at left
Coverage & restrictions
of plans cover it

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 3 quarters since 2024.

NADAC price per unit

$0$5.00$10.00$15.00Nov 2013Feb 2022$11.63
14 price points · per · last surveyed Invalid Date · dashed = manufacturer avg (WAMP)Source: CMS NADAC

Estimated fill cost

WAC per package, as filed
$549.05
Reported to Texas DSHS · 2026 annual filing · Galderma Laboratories, L.P.

Manufacturer list price as filed — not what pharmacies actually pay after discounts.

Medicaid spend (2025)

$21,118
42 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

Not scored — fragility is computed for NADAC-priced NDCs.

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for adapalene (other) in the next 90 days

sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Where it's made

Establishments this product's FDA label declares, located via FDA registration data. How we built this →

Regulatory

Application
NDA021753
TE code
AB
Approval date
Jun 19, 2007
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of adapalene (Gel)

LabelerStrengthFirst seenLast seen
LOreal USA Products IncADAPALENE 1 mg/gJul 15, 2026Sep 3, 2026
P & L Development, LLCADAPALENE 1 mg/gJul 15, 2026Sep 3, 2026
Actavis Pharma, Inc.ADAPALENE 3 mg/gJul 15, 2026Sep 2, 2026
Alchemee, LLCADAPALENE .1 g/100gJul 15, 2026Sep 2, 2026
Alembic Pharmaceuticals Inc.ADAPALENE 3 mg/gJul 15, 2026Sep 2, 2026
Alembic Pharmaceuticals LimitedADAPALENE 3 mg/gJul 15, 2026Sep 2, 2026
Amerisource BergenADAPALENE 1 mg/gJul 15, 2026Sep 2, 2026
Cardinal HealthADAPALENE 1 mg/gJul 15, 2026Sep 2, 2026
CVS PharmacyADAPALENE 1 mg/gJul 15, 2026Sep 2, 2026
Cvs Pharmacy, IncADAPALENE 1 mg/gJul 15, 2026Sep 2, 2026
Dolgencorp, Inc. (DOLLAR GENERAL & REXALL)ADAPALENE 1 mg/gJul 15, 2026Sep 2, 2026
Galderma Laboratories, L.P.ADAPALENE 3 mg/gJul 15, 2026Sep 2, 2026
Galderma Laboratories, L.P.ADAPALENE 1 mg/gJul 15, 2026Sep 2, 2026
Little Pharma, Inc.ADAPALENE .1 g/100gJul 15, 2026Sep 2, 2026
Mayne Pharma Commercial LLC.ADAPALENE 3 mg/gJul 15, 2026Sep 2, 2026
Meijer Distribution Inc.ADAPALENE 1 mg/gJul 15, 2026Sep 2, 2026
Meijer, Inc.ADAPALENE 1 mg/gJul 15, 2026Sep 2, 2026
Rite AidADAPALENE 1 mg/gJul 15, 2026Sep 2, 2026
Rugby Laboratories, Inc.ADAPALENE 1 mg/gJul 15, 2026Sep 2, 2026
Safeway, Inc.ADAPALENE 1 mg/gJul 15, 2026Sep 2, 2026
Sun Pharmaceutical Industries, Inc.ADAPALENE 1 mg/gJul 15, 2026Sep 2, 2026
Sun Pharmaceutical Industries, Inc.ADAPALENE 3 mg/gJul 15, 2026Sep 2, 2026
Target CorporationADAPALENE 1 mg/gJul 15, 2026Sep 2, 2026
The Kroger Co.ADAPALENE 1 mg/gJul 15, 2026Sep 2, 2026
TOP CARE (Topco Associates LLC)ADAPALENE 1 mg/gJul 15, 2026Sep 2, 2026
Topco AssociatesADAPALENE 1 mg/gJul 15, 2026Sep 2, 2026
Wal-Mart Stores IncADAPALENE 1 mg/gJul 15, 2026Sep 2, 2026
Crown LaboratoriesADAPALENE 1 mg/gJul 15, 2026Aug 31, 2026
Glenmark Therapeutics Inc., UsaADAPALENE 1 mg/gJul 15, 2026Aug 31, 2026
Kenvue Brands LLCADAPALENE 1 mg/gJul 15, 2026Aug 31, 2026
WalgreensADAPALENE 1 mg/gJul 15, 2026Aug 31, 2026
Yyba CorpADAPALENE 1 mg/gJul 15, 2026Aug 31, 2026
YYBA CorpADAPALENE 1 mg/gJul 15, 2026Aug 28, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Differin — NDC 00299-5918-25," retrieved September 3, 2026, https://drugdashboards.com/drug/00299591825.

Free to cite with attribution — see how the data is put together.