DrugDashboards

Travasol

Leucine, Phenylalanine, Lysine hydrochloride, Methionine, Isoleucine, Valine, Histidine, Threonine, Tryptophan, Alanine, Glycine, Arginine, Proline, Tyrosine, Serine · LEUCINE 730 mg/100mL; PHENYLALANINE 560 mg/100mL; LYSINE HYDROCHLORIDE 580 mg/100mL; METHIONINE 400 mg/100mL; ISOLEUCINE 600 mg/100mL; VALINE 580 mg/100mL; HISTIDINE 480 mg/100mL; THREONINE 420 mg/100mL; TRYPTOPHAN 180 mg/100mL; ALANINE 2.07 g/100mL; GLYCINE 1.03 g/100mL; ARGININE 1.15 g/100mL; PROLINE 680 mg/100mL; TYROSINE 40 mg/100mL; SERINE 500 mg/100mL · Injection · Intravenous · Baxter Healthcare Corporation

NDC 00338-0644-03 · 500 mL in 1 BAG · NDA · View full market →

The short version

Only one company currently supplies this market — there is no backup if it stumbles. It is in shortage right now — FDA lists the reason as “shortage of an inactive ingredient component”. One of its named manufacturing plants, Baxter Healthcare Corporation, failed FDA inspectionwithin the last two years — the agency’s most serious outcome.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Part D plans paid (avg)$0.0521per dosage unitgross, before rebates — matched by drug name · 2024
  • Federal contracts pay (FSS)$193.44per package of 24X500MLBaxter Healthcare Corporation · Sep 17, 2025

Medicare Part D

All Part D pricing →

Matched to CMS's representative package for this drug (NDC 00338-0644-06) — same generic, strength, and dosage form. CMS prices one NDC per drug concept, not every package.

ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of saleⓘ
$0.0299per unit
middle half $0.0285–$0.0469 · 5,151 plans · Apr 1, 2026
Est. net of rebatesⓘ
$0.0179–$0.0224
brand drug — est. 25-40% rebate off the price at left
Coverage & restrictions
94%of plans cover it
tier 4 · prior auth 97% · step therapy 0% · qty limit 0%

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.

NADAC price per unit

No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.

Estimated fill cost

WAC per package, as filed
$20.11
Reported to Texas DSHS · 2026 annual filing · Baxter Healthcare Corporation

Manufacturer list price as filed — not what pharmacies actually pay after discounts.

Medicaid spend (2025)

$3,719
14 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

Not scored — fragility is computed for NADAC-priced NDCs.

Where it's made

Establishments this product's FDA label declares, located via FDA registration data. How we built this →

Is this a "specialty" drug?

There's no legal definition — it meets 1 of 6 public criteria. Why that matters →

  • Part D specialty tier
  • Costs ≥ $950/fill · avg $294.99 per prescription
  • Biologic (BLA)
  • Injectable / infused
  • Orphan-drug exclusivity
  • REMS program

Regulatory

Application
NDA018931
TE code
—
Approval date
Aug 23, 1984
Patents / exclusivity
None on file

Shortage history

  • In shortage now — Travasol, Injection, 2.07 g/100 mL; 1.15 g/100 mL; 1.03 g/100 mL; 480 mg/100 mL; 600 mg/100 mL; 730 mg/100 mL; 580 mg/100 mL; 400 mg/100 mL; 560 mg/100 mL; 680 mg/100 mL; 500 mg/100 mL; 420 mg/100 mL; 180 mg/100 mL; 40 mg/100 mL; 580 mg/100 mL (NDC 0338-0644-03)Dec 8, 2020
    Shortage of an inactive ingredient component
    month 69 — 3× the typical 20-month injectable shortage
  • In shortage now — Travasol, Injection, 2.07 g/100 mL; 1.15 g/100 mL; 1.03 g/100 mL; 480 mg/100 mL; 600 mg/100 mL; 730 mg/100 mL; 580 mg/100 mL; 400 mg/100 mL; 560 mg/100 mL; 680 mg/100 mL; 500 mg/100 mL; 420 mg/100 mL; 180 mg/100 mL; 40 mg/100 mL; 580 mg/100 mL (NDC 0338-0644-04)Dec 8, 2020
    month 69 — 3× the typical 20-month injectable shortage
  • In shortage now — Travasol, Injection, 2.07 g/100 mL; 1.15 g/100 mL; 1.03 g/100 mL; 480 mg/100 mL; 600 mg/100 mL; 730 mg/100 mL; 580 mg/100 mL; 400 mg/100 mL; 560 mg/100 mL; 680 mg/100 mL; 500 mg/100 mL; 420 mg/100 mL; 180 mg/100 mL; 40 mg/100 mL; 580 mg/100 mL (NDC 0338-0644-06)Dec 8, 2020
    month 69 — 3× the typical 20-month injectable shortage

Recalls (this NDC)

  • Class II · TerminatedNov 12, 2013
    Baxter Healthcare Corp. — Lack of Assurance of Sterility; Drug product leaking from container therefore sterility cannot be assured

Manufacturers of Leucine, Phenylalanine, Lysine hydrochloride, Methionine, Isoleucine, Valine, Histidine, Threonine, Tryptophan, Alanine, Glycine, Arginine, Proline, Tyrosine, Serine (Injection)

LabelerStrengthFirst seenLast seen
Baxter Healthcare CorporationLEUCINE 730 mg/100mL; PHENYLALANINE 560 mg/100mL; LYSINE HYDROCHLORIDE 580 mg/100mL; METHIONINE 400 mg/100mL; ISOLEUCINE 600 mg/100mL; VALINE 580 mg/100mL; HISTIDINE 480 mg/100mL; THREONINE 420 mg/100mL; TRYPTOPHAN 180 mg/100mL; ALANINE 2.07 g/100mL; GLYCINE 1.03 g/100mL; ARGININE 1.15 g/100mL; PROLINE 680 mg/100mL; TYROSINE 40 mg/100mL; SERINE 500 mg/100mLAug 26, 2026Sep 2, 2026
Baxter Healthcare CorporationLEUCINE 2.07 g/100mL; PHENYLALANINE 1.15 g/100mL; LYSINE HYDROCHLORIDE 1.03 g/100mL; METHIONINE 480 mg/100mL; ISOLEUCINE 600 mg/100mL; VALINE 730 mg/100mL; HISTIDINE 580 mg/100mL; THREONINE 400 mg/100mL; TRYPTOPHAN 560 mg/100mL; ALANINE 680 mg/100mL; GLYCINE 500 mg/100mL; ARGININE 420 mg/100mL; PROLINE 180 mg/100mL; TYROSINE 40 mg/100mL; SERINE 580 mg/100mLJul 22, 2026Aug 19, 2026
Baxter Healthcare CorporationALANINE 2.07 g/100mL; ARGININE 1.15 g/100mL; GLYCINE 1.03 g/100mL; HISTIDINE 480 mg/100mL; ISOLEUCINE 600 mg/100mL; LEUCINE 730 mg/100mL; LYSINE HYDROCHLORIDE 580 mg/100mL; METHIONINE 400 mg/100mL; PHENYLALANINE 560 mg/100mL; PROLINE 680 mg/100mL; SERINE 500 mg/100mL; THREONINE 420 mg/100mL; TRYPTOPHAN 180 mg/100mL; TYROSINE 40 mg/100mL; VALINE 580 mg/100mLJul 15, 2026Jul 15, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Travasol — NDC 00338-0644-03," retrieved September 3, 2026, https://drugdashboards.com/drug/00338064403.

Free to cite with attribution — see how the data is put together.