The short version
Only one company currently supplies this market — there is no backup if it stumbles.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
Cold and Flu Severe
Acetaminophen, Dextromethorphan HBr, Phenylephrine HCl, Triprolidine HCl · ACETAMINOPHEN 650 mg/20mL; DEXTROMETHORPHAN HYDROBROMIDE 20 mg/20mL; PHENYLEPHRINE HYDROCHLORIDE 10 mg/20mL; TRIPROLIDINE HYDROCHLORIDE 2.5 mg/20mL · Solution · Oral · Walgreen Company
NDC 00363-8078-45 · 177 mL in 1 BOTTLE, PLASTIC · OTC MONOGRAPH DRUG · View full market →
Medicare Part D
Medicare Part D does not cover over-the-counter drugs — by law it pays only for products requiring a prescription.
How Part D pricing works →NADAC price per unit
No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.
Supply fragility
Not scored — fragility is computed for NADAC-priced NDCs.
Is this a "specialty" drug?
There's no legal definition — it meets 1 of 6 public criteria. Why that matters →
- Part D specialty tier
- Costs ≥ $950/fill
- Biologic (BLA)
- Injectable / infused
- Orphan-drug exclusivity
- REMS program · Opioid Analgesic REMS Shared System REMS
Regulatory
- Application
- M012
- TE code
- —
- Approval date
- —
- Patents / exclusivity
- None on file
Shortage history
No FDA shortage reports for this drug or its presentations.
Recalls (this NDC)
No enforcement reports list this package NDC.
Manufacturers of Acetaminophen, Dextromethorphan HBr, Phenylephrine HCl, Triprolidine HCl (Solution)
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| Walgreen Company | ACETAMINOPHEN 650 mg/20mL; DEXTROMETHORPHAN HYDROBROMIDE 20 mg/20mL; PHENYLEPHRINE HYDROCHLORIDE 10 mg/20mL; TRIPROLIDINE HYDROCHLORIDE 2.5 mg/20mL | Jul 15, 2026 | Sep 2, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
Cite this page
DrugDashboards, "Cold and Flu Severe — NDC 00363-8078-45," retrieved September 3, 2026, https://drugdashboards.com/drug/00363807845.
Free to cite with attribution — see how the data is put together.