DrugDashboards

Carbidopa and Levodopa

carbidopa and levodopa · CARBIDOPA 25 mg/1; LEVODOPA 100 mg/1 · Tablet, Extended Release · Oral · Mylan Pharmaceuticals Inc.

NDC 00378-0088-01 · 100 TABLET, EXTENDED RELEASE in 1 BOTTLE, PLASTIC · ANDA · View full market →

The short version

13 companies supply this market — deep enough that no single failure threatens the supply. The price is down 20% over the past year, to $0.1137 per unit. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$0.1137per EAinvoice-surveyed acquisition cost · Aug 19, 2026
  • Medicaid generic ceiling (FUL)$0.1137per TABweighted avg manufacturer price $0.0428 · Aug 1, 2026100% of what pharmacies pay — higher than 10% of drugs with this benchmark

Medicare Part D

No Medicare Part D plan in CMS's quarterly files lists this product. That usually means it is discontinued, a repackager's listing, or a product no plan has added to its formulary.

How Part D pricing works →

NADAC price per unit

$0$0.2$0.4Nov 2013Sep 2026$0.1137
155 price points · per EA · dashed = manufacturer avg (WAMP)Source: CMS NADAC

Estimated fill cost

#30 count
$3.41
#90 count
$10.23

Estimates: latest NADAC unit price × quantity. Pharmacy acquisition cost only — excludes dispensing fees, markup, and insurance terms.

Medicaid spend (2025)

$1,299
60 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

0● Low risk

Nothing here is signaling trouble: several manufacturers, no current shortage, no recent serious recalls, stable pricing. In drug supply, boring is the good outcome.

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for carbidopa and levodopa (oral solid) in the next 90 days

OAI inspection at a producing facility (24 months) · sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Regulatory

Application
ANDA075091
TE code
AB
Approval date
Sep 30, 1999
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of carbidopa and levodopa (Tablet, Extended Release)

LabelerStrengthFirst seenLast seen
Accord Healthcare, Inc.CARBIDOPA 50 mg/1; LEVODOPA 200 mg/1Jul 15, 2026Sep 2, 2026
Accord Healthcare, Inc.CARBIDOPA 25 mg/1; LEVODOPA 100 mg/1Jul 15, 2026Sep 2, 2026
Advagen Pharma LtdCARBIDOPA 50 mg/1; LEVODOPA 200 mg/1Jul 15, 2026Sep 2, 2026
Advagen Pharma LtdCARBIDOPA 25 mg/1; LEVODOPA 100 mg/1Jul 15, 2026Sep 2, 2026
Alembic Pharmaceuticals Inc.CARBIDOPA 50 mg/1; LEVODOPA 200 mg/1Jul 15, 2026Sep 2, 2026
Alembic Pharmaceuticals Inc.CARBIDOPA 25 mg/1; LEVODOPA 100 mg/1Jul 15, 2026Sep 2, 2026
Alembic Pharmaceuticals LimitedCARBIDOPA 50 mg/1; LEVODOPA 200 mg/1Jul 15, 2026Sep 2, 2026
Alembic Pharmaceuticals LimitedCARBIDOPA 25 mg/1; LEVODOPA 100 mg/1Jul 15, 2026Sep 2, 2026
Amneal Pharmaceuticals NY LLCCARBIDOPA HYDRATE 25 mg/1; LEVODOPA 100 mg/1Jul 15, 2026Sep 2, 2026
Amneal Pharmaceuticals NY LLCCARBIDOPA HYDRATE 50 mg/1; LEVODOPA 200 mg/1Jul 15, 2026Sep 2, 2026
Bryant Ranch PrepackCARBIDOPA 50 mg/1; LEVODOPA 200 mg/1Jul 15, 2026Sep 2, 2026
Bryant Ranch PrepackCARBIDOPA 25 mg/1; LEVODOPA 100 mg/1Jul 15, 2026Sep 2, 2026
Mylan Institutional Inc.CARBIDOPA 50 mg/1; LEVODOPA 200 mg/1Jul 15, 2026Sep 2, 2026
Mylan Institutional Inc.CARBIDOPA 25 mg/1; LEVODOPA 100 mg/1Jul 15, 2026Sep 2, 2026
Mylan Pharmaceuticals Inc.CARBIDOPA 25 mg/1; LEVODOPA 100 mg/1Jul 15, 2026Sep 2, 2026
Mylan Pharmaceuticals Inc.CARBIDOPA 50 mg/1; LEVODOPA 200 mg/1Jul 15, 2026Sep 2, 2026
NCS HealthCare of KY, LLC dba Vangard LabsCARBIDOPA 25 mg/1; LEVODOPA 100 mg/1Jul 15, 2026Sep 2, 2026
NCS HealthCare of KY, LLC dba Vangard LabsCARBIDOPA 50 mg/1; LEVODOPA 200 mg/1Jul 15, 2026Sep 2, 2026
Radha Pharmaceuticals IncCARBIDOPA 25 mg/1; LEVODOPA 100 mg/1Jul 15, 2026Sep 2, 2026
Radha Pharmaceuticals IncCARBIDOPA 50 mg/1; LEVODOPA 200 mg/1Jul 15, 2026Sep 2, 2026
Safecor Health, LLCCARBIDOPA HYDRATE 25 mg/1; LEVODOPA 100 mg/1Jul 15, 2026Sep 2, 2026
Safecor Health, LLCCARBIDOPA HYDRATE 50 mg/1; LEVODOPA 200 mg/1Jul 15, 2026Sep 2, 2026
ScieGen Pharmaceuticals IncCARBIDOPA 50 mg/1; LEVODOPA 200 mg/1Jul 15, 2026Sep 2, 2026
ScieGen Pharmaceuticals IncCARBIDOPA 25 mg/1; LEVODOPA 100 mg/1Jul 15, 2026Sep 2, 2026
Sun Pharmaceutical Industries, Inc.CARBIDOPA 25 mg/1; LEVODOPA 100 mg/1Jul 15, 2026Sep 2, 2026
Sun Pharmaceutical Industries, Inc.CARBIDOPA 50 mg/1; LEVODOPA 200 mg/1Jul 15, 2026Sep 2, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Carbidopa and Levodopa — NDC 00378-0088-01," retrieved September 3, 2026, https://drugdashboards.com/drug/00378008801.

Free to cite with attribution — see how the data is put together.