DrugDashboards

Ambrisentan

ambrisentan · AMBRISENTAN 10 mg/1 · Tablet, Film Coated · Oral · Mylan Pharmaceuticals Inc.

NDC 00378-4271-93 · 30 TABLET, FILM COATED in 1 BOTTLE, PLASTIC · ANDA · View full market →

The short version

13 companies supply this market — deep enough that no single failure threatens the supply. The price is down 17% over the past year, to $8.21 per unit. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$8.21per EAinvoice-surveyed acquisition cost · Aug 19, 2026
  • Part D plans paid (avg)$99.24per dosage unitgross, before rebates — matched by drug name · 2024
  • Medicaid generic ceiling (FUL)$113.99per TABweighted avg manufacturer price $65.1363 · Aug 1, 20261389% of what pharmacies pay — higher than 95% of drugs with this benchmark

Medicare Part D

All Part D pricing →

Matched to CMS's representative package for this drug (NDC 61958-0802-01) — same generic, strength, and dosage form. CMS prices one NDC per drug concept, not every package.

ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$491.02per unit
middle half $490.59$491.02 · 8 plans · Apr 1, 2026
Est. net of rebates
≈ $491.02
generic — rebates are minimal, so net ≈ gross
Coverage & restrictions
0%of plans cover it
tier 5 · prior auth 100% · step therapy 0% · qty limit 25%

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.

NADAC price per unit

$0$100.00$200.00$300.00Nov 2025Sep 2026$8.21
10 price points · per EA · dashed = manufacturer avg (WAMP)Source: CMS NADAC

Estimated fill cost

#30 count
$246.28
#90 count
$738.85

Estimates: latest NADAC unit price × quantity. Pharmacy acquisition cost only — excludes dispensing fees, markup, and insurance terms.

Medicaid spend (2025)

$1.5M
1,347 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

0Low risk

Nothing here is signaling trouble: several manufacturers, no current shortage, no recent serious recalls, stable pricing. In drug supply, boring is the good outcome.

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for ambrisentan (oral solid) in the next 90 days

sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Is this a "specialty" drug?

There's no legal definition — it meets 1 of 6 public criteria. Why that matters →

  • Part D specialty tier
  • Costs ≥ $950/fill · avg $3,148.66 per prescription
  • Biologic (BLA)
  • Injectable / infused
  • Orphan-drug exclusivity
  • REMS program

Regulatory

Application
ANDA208441
TE code
AB
Approval date
Mar 28, 2019
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of ambrisentan (Tablet, Film Coated)

LabelerStrengthFirst seenLast seen
A-S Medication SolutionsAMBRISENTAN 10 mg/1Jul 15, 2026Sep 2, 2026
A-S Medication SolutionsAMBRISENTAN 5 mg/1Jul 15, 2026Sep 2, 2026
Apotex Corp.AMBRISENTAN 10 mg/1Jul 15, 2026Sep 2, 2026
Apotex Corp.AMBRISENTAN 5 mg/1Jul 15, 2026Sep 2, 2026
Aurobindo Pharma LimitedAMBRISENTAN 10 mg/1Jul 15, 2026Sep 2, 2026
Aurobindo Pharma LimitedAMBRISENTAN 5 mg/1Jul 15, 2026Sep 2, 2026
Cipla USA Inc.AMBRISENTAN 10 mg/1Jul 15, 2026Sep 2, 2026
Cipla USA Inc.AMBRISENTAN 5 mg/1Jul 15, 2026Sep 2, 2026
Gilead Sciences, Inc.AMBRISENTAN 10 mg/1Jul 15, 2026Sep 2, 2026
Gilead Sciences, Inc.AMBRISENTAN 5 mg/1Jul 15, 2026Sep 2, 2026
Golden State Medical Supply, Inc.AMBRISENTAN 10 mg/1Jul 15, 2026Sep 2, 2026
Golden State Medical Supply, Inc.AMBRISENTAN 5 mg/1Jul 15, 2026Sep 2, 2026
Mylan Pharmaceuticals Inc.AMBRISENTAN 10 mg/1Jul 15, 2026Sep 2, 2026
Mylan Pharmaceuticals Inc.AMBRISENTAN 5 mg/1Jul 15, 2026Sep 2, 2026
Quallent Pharmaceuticals Health LLCAMBRISENTAN 5 mg/1Jul 15, 2026Sep 2, 2026
Quallent Pharmaceuticals Health LLCAMBRISENTAN 10 mg/1Jul 15, 2026Sep 2, 2026
Sigmapharm Laboratories, LLCAMBRISENTAN 5 mg/1Jul 15, 2026Sep 2, 2026
Sigmapharm Laboratories, LLCAMBRISENTAN 10 mg/1Jul 15, 2026Sep 2, 2026
Sun Pharmaceutical Industries, Inc.AMBRISENTAN 10 mg/1Jul 15, 2026Sep 2, 2026
Sun Pharmaceutical Industries, Inc.AMBRISENTAN 5 mg/1Jul 15, 2026Sep 2, 2026
Zydus Lifesciences LimitedAMBRISENTAN 10 mg/1Jul 15, 2026Sep 2, 2026
Zydus Lifesciences LimitedAMBRISENTAN 5 mg/1Jul 15, 2026Sep 2, 2026
Zydus Pharmaceuticals USA Inc.AMBRISENTAN 10 mg/1Jul 15, 2026Sep 2, 2026
Zydus Pharmaceuticals USA Inc.AMBRISENTAN 5 mg/1Jul 15, 2026Sep 2, 2026
Actavis Pharma, Inc.AMBRISENTAN 10 mg/1Jul 15, 2026Aug 31, 2026
Actavis Pharma, Inc.AMBRISENTAN 5 mg/1Jul 15, 2026Aug 28, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Ambrisentan — NDC 00378-4271-93," retrieved September 3, 2026, https://drugdashboards.com/drug/00378427193.

Free to cite with attribution — see how the data is put together.