DrugDashboards

Tretinoin

Tretinoin · TRETINOIN .5 mg/g · Cream · Topical · Mylan Pharmaceuticals Inc.

NDC 00378-8083-20 · 1 TUBE in 1 CARTON / 20 g in 1 TUBE · NDA AUTHORIZED GENERIC · View full market →

The short version

18 companies supply this market — deep enough that no single failure threatens the supply. The price has held steady around $1.57 per gram over the past year. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$1.57per GMinvoice-surveyed acquisition cost · Aug 19, 2026
  • Part D plans paid (avg)$12.38per dosage unitgross, before rebates — matched by drug name · 2024
  • Federal ceiling (Big4)$3.94per package of 20GMMylan Pharmaceuticals, Inc. · Jan 1, 2026

Medicare Part D

All Part D pricing →

Matched to CMS's representative package for this drug (NDC 00187-5162-20) — same generic, strength, and dosage form. CMS prices one NDC per drug concept, not every package.

ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$0.7232per unit
middle half $0.7224$0.7232 · 117 plans · Apr 1, 2026
Est. net of rebates
≈ $0.7232
generic — rebates are minimal, so net ≈ gross
Coverage & restrictions
2%of plans cover it
tier 2 · prior auth 86% · step therapy 0% · qty limit 2%

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.

NADAC price per unit

$0$2.00$4.00Sep 2019Sep 2026$1.57
85 price points · per GMSource: CMS NADAC

Estimated fill cost

WAC per package, as filed
$93.88
Reported to Texas DSHS · 2026 annual filing · Mylan Pharmaceuticals Inc.

Manufacturer list price as filed — not what pharmacies actually pay after discounts.

Medicaid spend (2025)

$565,208
14,514 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

0Low risk

Nothing here is signaling trouble: several manufacturers, no current shortage, no recent serious recalls, stable pricing. In drug supply, boring is the good outcome.

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for tretinoin (other) in the next 90 days

sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Where it's made

Establishments this product's FDA label declares, located via FDA registration data. How we built this →

Regulatory

Application
NDA017522
TE code
AB1
Approval date
Jan 1, 1982
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of Tretinoin (Cream)

LabelerStrengthFirst seenLast seen
A-S Medication SolutionsTRETINOIN .25 mg/gJul 15, 2026Sep 3, 2026
A-S Medication SolutionsTRETINOIN 1 mg/gJul 15, 2026Sep 2, 2026
Actavis Pharma, Inc.TRETINOIN .25 mg/gJul 15, 2026Sep 2, 2026
Alembic Pharmaceuticals Inc.TRETINOIN 1 mg/gJul 15, 2026Sep 2, 2026
Alembic Pharmaceuticals Inc.TRETINOIN .25 mg/gJul 15, 2026Sep 2, 2026
Alembic Pharmaceuticals Inc.TRETINOIN .5 mg/gJul 15, 2026Sep 2, 2026
Alembic Pharmaceuticals LimitedTRETINOIN .5 mg/gJul 15, 2026Sep 2, 2026
Alembic Pharmaceuticals LimitedTRETINOIN .25 mg/gJul 15, 2026Sep 2, 2026
Alembic Pharmaceuticals LimitedTRETINOIN 1 mg/gJul 15, 2026Sep 2, 2026
Bausch Health US LLCTRETINOIN .2 mg/gJul 15, 2026Sep 2, 2026
Bausch Health US, LLCTRETINOIN 1 mg/gJul 15, 2026Sep 2, 2026
Bausch Health US, LLCTRETINOIN .5 mg/gJul 15, 2026Sep 2, 2026
Bausch Health US, LLCTRETINOIN .25 mg/gJul 15, 2026Sep 2, 2026
Bryant Ranch PrepackTRETINOIN .25 mg/gJul 15, 2026Sep 2, 2026
Bryant Ranch PrepackTRETINOIN .5 mg/gJul 15, 2026Sep 2, 2026
Encube Ethicals, Inc.TRETINOIN .25 mg/gJul 15, 2026Sep 2, 2026
Encube Ethicals, Inc.TRETINOIN 1 mg/gJul 15, 2026Sep 2, 2026
Encube Ethicals, Inc.TRETINOIN .5 mg/gJul 15, 2026Sep 2, 2026
Mylan Pharmaceuticals Inc.TRETINOIN 1 mg/gJul 15, 2026Sep 2, 2026
Mylan Pharmaceuticals Inc.TRETINOIN .5 mg/gJul 15, 2026Sep 2, 2026
Mylan Pharmaceuticals Inc.TRETINOIN .25 mg/gJul 15, 2026Sep 2, 2026
Northstar Rx LlcTRETINOIN .25 mg/gJul 15, 2026Sep 2, 2026
Northstar Rx LlcTRETINOIN .5 mg/gJul 15, 2026Sep 2, 2026
Northstar Rx LlcTRETINOIN 1 mg/gJul 15, 2026Sep 2, 2026
NuCare Pharmaceuticals, Inc.TRETINOIN 1 mg/gJul 15, 2026Sep 2, 2026
NuCare Pharmaceuticals, Inc.TRETINOIN .25 mg/gJul 15, 2026Sep 2, 2026
NuCare Pharmaceuticals,Inc.TRETINOIN 1 mg/gJul 15, 2026Sep 2, 2026
NuCare Pharmaceuticals,Inc.TRETINOIN .5 mg/gJul 15, 2026Sep 2, 2026
Obagi Cosmeceuticals LLCTRETINOIN 1 mg/gJul 15, 2026Sep 2, 2026
Obagi Cosmeceuticals LLCTRETINOIN .5 mg/gJul 15, 2026Sep 2, 2026
Obagi Cosmeceuticals LLCTRETINOIN .25 mg/gJul 15, 2026Sep 2, 2026
Padagis US LLCTRETINOIN .25 mg/gJul 15, 2026Sep 2, 2026
Padagis US LLCTRETINOIN .5 mg/gJul 15, 2026Sep 2, 2026
Padagis US LLCTRETINOIN 1 mg/gJul 15, 2026Sep 2, 2026
Remedyrepack Inc.TRETINOIN 1 mg/gJul 15, 2026Sep 2, 2026
Sun Pharmaceutical Industries, Inc.TRETINOIN .25 mg/gJul 15, 2026Sep 2, 2026
Sun Pharmaceutical Industries, Inc.TRETINOIN 1 mg/gJul 15, 2026Sep 2, 2026
Sun Pharmaceutical Industries, Inc.TRETINOIN .5 mg/gJul 15, 2026Sep 2, 2026
Viona Pharmaceuticals IncTRETINOIN 1 mg/gJul 15, 2026Sep 2, 2026
Zydus Lifesciences LimitedTRETINOIN 1 mg/gJul 15, 2026Sep 2, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Tretinoin — NDC 00378-8083-20," retrieved September 3, 2026, https://drugdashboards.com/drug/00378808320.

Free to cite with attribution — see how the data is put together.