DrugDashboards

Epinephrine

Epinephrine · EPINEPHRINE 1 mg/mL · Injection, Solution, Concentrate · Intravenous · Henry Schein, Inc.

NDC 00404-9857-01 · 1 AMPULE in 1 BAG / 1 mL in 1 AMPULE · NDA · View full market →

The short version

11 companies supply this market — deep enough that no single failure threatens the supply. Historically, drugs in this position went on to a new shortage within 90 days about 0.5% of the time — roughly 4× the typical drug (0.1%).

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Medicare Part B pays (ASP+6%)$0.6690per billing unit (0.1 MG)HCPCS J0166 · Jul 1, 2026
  • Part D plans paid (avg)$99.63per dosage unitgross, before rebates — matched by drug name · 2024

Medicare Part D

No Medicare Part D plan in CMS's quarterly files lists this product. That usually means it is discontinued, a repackager's listing, or a product no plan has added to its formulary.

How Part D pricing works →

NADAC price per unit

No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.

Medicare Part B (ASP)

Payment limit per 0.1 MG
$0.669
HCPCS J0166 · Jul 1, 2026 quarter · typically ASP + 6%

Supply fragility

Not scored — fragility is computed for NADAC-priced NDCs.

90-day shortage risk (model v2)

0.5%chance of a new FDA shortage posting for epinephrine (injectable) in the next 90 days

sterile injectable · OAI inspection at a producing facility (24 months) · sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is 4× that.

Backtested statistical model over the whole market, not this package alone. Model details →

Is this a "specialty" drug?

There's no legal definition — it meets 1 of 6 public criteria. Why that matters →

  • Part D specialty tier
  • Costs ≥ $950/fill · avg $206.21 per prescription
  • Biologic (BLA)
  • Injectable / infused
  • Orphan-drug exclusivity
  • REMS program

Regulatory

Application
NDA205029
TE code
AP
Approval date
Jul 29, 2014
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of Epinephrine (Injection, Solution, Concentrate)

LabelerStrengthFirst seenLast seen
Baxter Healthcare CorporationEPINEPHRINE 1 mg/mLJul 15, 2026Sep 3, 2026
A-S Medication SolutionsEPINEPHRINE 1 mg/mLJul 15, 2026Sep 2, 2026
BPI Labs, LLCEPINEPHRINE 1 mg/mLJul 15, 2026Sep 2, 2026
Civica, Inc.EPINEPHRINE 1 mg/mLJul 15, 2026Sep 2, 2026
Gland Pharma LimitedEPINEPHRINE 1 mg/mLJul 15, 2026Sep 2, 2026
Glenmark Pharmaceuticals Inc., UsaEPINEPHRINE 1 mg/mLJul 15, 2026Sep 2, 2026
Henry Schein, Inc.EPINEPHRINE 1 mg/mLJul 15, 2026Sep 2, 2026
Medical Purchasing Solutions, LLCEPINEPHRINE 1 mg/mLJul 15, 2026Sep 2, 2026
ProPharma DistributionEPINEPHRINE 1 mg/mLJul 15, 2026Sep 2, 2026
Remedyrepack Inc.EPINEPHRINE 1 mg/mLJul 15, 2026Sep 2, 2026
Fresenius Kabi USA, LLCEPINEPHRINE 1 mg/mLJul 15, 2026Aug 28, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Epinephrine — NDC 00404-9857-01," retrieved September 3, 2026, https://drugdashboards.com/drug/00404985701.

Free to cite with attribution — see how the data is put together.