DrugDashboards

Vancomycin Hydrochloride

Vancomycin Hydrochloride · VANCOMYCIN HYDROCHLORIDE 500 mg/1 · Injection, Powder, Lyophilized, For Solution · Intravenous · Henry Schein, Inc.

NDC 00404-9965-99 · 1 VIAL in 1 BAG / 1 INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION in 1 VIAL · ANDA · View full market →

The short version

12 companies supply this market — deep enough that no single failure threatens the supply. Historically, drugs in this position went on to a new shortage within 90 days about 0.5% of the time — roughly 3× the typical drug (0.1%).

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

Medicare Part D

All Part D pricing →

Matched to CMS's representative package for this drug (NDC 00409-4332-01) — same generic, strength, and dosage form. CMS prices one NDC per drug concept, not every package.

ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of saleⓘ
$3.67per unit
middle half $3.34–$5.43 · 5,476 plans · Apr 1, 2026
Est. net of rebatesⓘ
≈ $3.67
generic — rebates are minimal, so net ≈ gross
Coverage & restrictions
100%of plans cover it
tier 4 · prior auth 0% · step therapy 0% · qty limit 8%

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.

NADAC price per unit

No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.

Medicare Part B (ASP)

Payment limit per 10 MG
$0.033
HCPCS J3373 · Jul 1, 2026 quarter · typically ASP + 6%

Supply fragility

Not scored — fragility is computed for NADAC-priced NDCs.

90-day shortage risk (model v2)

0.5%chance of a new FDA shortage posting for vancomycin hydrochloride (injectable) in the next 90 days

sterile injectable · OAI inspection at a producing facility (24 months) · sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is 3× that.

Backtested statistical model over the whole market, not this package alone. Model details →

Is this a "specialty" drug?

There's no legal definition — it meets 1 of 6 public criteria. Why that matters →

  • Part D specialty tier
  • Costs ≥ $950/fill
  • Biologic (BLA)
  • Injectable / infused
  • Orphan-drug exclusivity
  • REMS program

Regulatory

Application
ANDA062911
TE code
AP
Approval date
Aug 4, 1988
Patents / exclusivity
None on file

Shortage history

  • Planned discontinuation — Vancomycin Hydrochloride, Injection, 10 g Vial NovaPlus (NDC 0409-5017-01)Nov 14, 2025

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of Vancomycin Hydrochloride (Injection, Powder, Lyophilized, For Solution)

LabelerStrengthFirst seenLast seen
Fresenius Kabi USA, LLCVANCOMYCIN HYDROCHLORIDE 750 mg/15mLJul 15, 2026Sep 3, 2026
Fresenius Kabi USA, LLCVANCOMYCIN HYDROCHLORIDE 10 g/100mLJul 15, 2026Sep 3, 2026
Fresenius Kabi USA, LLCVANCOMYCIN HYDROCHLORIDE 1 g/20mLJul 15, 2026Sep 3, 2026
Fresenius Kabi USA, LLCVANCOMYCIN HYDROCHLORIDE 5 g/100mLJul 15, 2026Sep 3, 2026
Fresenius Kabi USA, LLCVANCOMYCIN HYDROCHLORIDE 500 mg/10mLJul 15, 2026Sep 3, 2026
Fresenius Kabi, LLCVANCOMYCIN HYDROCHLORIDE 500 mg/10mLJul 15, 2026Sep 3, 2026
Hospira, Inc.VANCOMYCIN HYDROCHLORIDE 500 mg/10mLJul 15, 2026Sep 3, 2026
BluePoint LaboratoriesVANCOMYCIN HYDROCHLORIDE 5 g/1Jul 15, 2026Sep 2, 2026
BluePoint LaboratoriesVANCOMYCIN HYDROCHLORIDE 10 g/1Jul 15, 2026Sep 2, 2026
Camber Pharmaceuticals, Inc.VANCOMYCIN HYDROCHLORIDE 500 mg/10mLJul 15, 2026Sep 2, 2026
Camber Pharmaceuticals, Inc.VANCOMYCIN HYDROCHLORIDE 1 g/20mLJul 15, 2026Sep 2, 2026
Civica, IncVANCOMYCIN HYDROCHLORIDE 1 g/1Jul 15, 2026Sep 2, 2026
Civica, IncVANCOMYCIN HYDROCHLORIDE 500 mg/5mLJul 15, 2026Sep 2, 2026
Civica, IncVANCOMYCIN HYDROCHLORIDE 500 mg/10mLJul 15, 2026Sep 2, 2026
Eugia US LLCVANCOMYCIN HYDROCHLORIDE 1.5 g/30mLJul 15, 2026Sep 2, 2026
Eugia US LLCVANCOMYCIN HYDROCHLORIDE 5 g/1Jul 15, 2026Sep 2, 2026
Eugia US LLCVANCOMYCIN HYDROCHLORIDE 1.25 g/25mLJul 15, 2026Sep 2, 2026
Eugia US LLCVANCOMYCIN HYDROCHLORIDE 500 mg/10mLJul 15, 2026Sep 2, 2026
Eugia US LLCVANCOMYCIN HYDROCHLORIDE 1 g/20mLJul 15, 2026Sep 2, 2026
Eugia US LLCVANCOMYCIN HYDROCHLORIDE 10 g/1Jul 15, 2026Sep 2, 2026
Eurofarma, Inc.VANCOMYCIN HYDROCHLORIDE 500 mg/10mLJul 15, 2026Sep 2, 2026
Eurofarma, Inc.VANCOMYCIN HYDROCHLORIDE 1 g/20mLJul 15, 2026Sep 2, 2026
Fresenius Kabi, LLCVANCOMYCIN HYDROCHLORIDE 1 g/20mLJul 15, 2026Sep 2, 2026
Fresenius Kabi, LLCVANCOMYCIN HYDROCHLORIDE 10 g/100mLJul 15, 2026Sep 2, 2026
Gland Pharma LimitedVANCOMYCIN HYDROCHLORIDE 500 mg/10mLJul 15, 2026Sep 2, 2026
Gland Pharma LimitedVANCOMYCIN HYDROCHLORIDE 1 g/20mLJul 15, 2026Sep 2, 2026
Gland Pharma LimitedVANCOMYCIN HYDROCHLORIDE 1.5 g/1Jul 15, 2026Sep 2, 2026
Gland Pharma LimitedVANCOMYCIN HYDROCHLORIDE 10 g/100mLJul 15, 2026Sep 2, 2026
Gland Pharma LimitedVANCOMYCIN HYDROCHLORIDE 1.25 g/1Jul 15, 2026Sep 2, 2026
Gland Pharma LimitedVANCOMYCIN HYDROCHLORIDE 5 g/100mLJul 15, 2026Sep 2, 2026
Gland Pharma LimitedVANCOMYCIN HYDROCHLORIDE 750 mg/1Jul 15, 2026Sep 2, 2026
Glenmark Pharmaceuticals Inc., UsaVANCOMYCIN HYDROCHLORIDE 1.5 g/1Jul 15, 2026Sep 2, 2026
Glenmark Pharmaceuticals Inc., UsaVANCOMYCIN HYDROCHLORIDE 1 g/20mLJul 15, 2026Sep 2, 2026
Glenmark Pharmaceuticals Inc., UsaVANCOMYCIN HYDROCHLORIDE 750 mg/1Jul 15, 2026Sep 2, 2026
Glenmark Pharmaceuticals Inc., UsaVANCOMYCIN HYDROCHLORIDE 1.25 g/1Jul 15, 2026Sep 2, 2026
Glenmark Pharmaceuticals Inc., UsaVANCOMYCIN HYDROCHLORIDE 500 mg/10mLJul 15, 2026Sep 2, 2026
Henry Schein, Inc.VANCOMYCIN HYDROCHLORIDE 500 mg/1Jul 15, 2026Sep 2, 2026
Hikma Pharmaceuticals USA Inc.VANCOMYCIN HYDROCHLORIDE 1.5 g/1Jul 15, 2026Sep 2, 2026
Hikma Pharmaceuticals USA Inc.VANCOMYCIN HYDROCHLORIDE 1.25 g/1Jul 15, 2026Sep 2, 2026
Hikma Pharmaceuticals USA Inc.VANCOMYCIN 750 mg/1Jul 15, 2026Sep 2, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Vancomycin Hydrochloride — NDC 00404-9965-99," retrieved September 3, 2026, https://drugdashboards.com/drug/00404996599.

Free to cite with attribution — see how the data is put together.