DrugDashboards

Acetaminophen And Codeine Phosphate

acetaminophen and codeine phosphate · ACETAMINOPHEN 300 mg/1; CODEINE PHOSPHATE 60 mg/1 · Tablet · Oral · SpecGx LLC

NDC 00406-0485-01 · 100 TABLET in 1 BOTTLE · ANDA · View full market →

The short version

22 companies supply this market — deep enough that no single failure threatens the supply. The price is down 12% over the past year, to $0.3809 per unit. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$0.3809per EAinvoice-surveyed acquisition cost · Aug 19, 2026
  • Part D point of sale (median)$0.4777per unitnegotiated price across 5,496 plans — before rebates · Apr 1, 2026
  • Federal contracts pay (FSS)$0.3325per unitSpecGx LLC · Jul 31, 202587% of what pharmacies pay — a deeper discount than 52% of drugs with this benchmark
  • Medicaid generic ceiling (FUL)$0.3809per TABweighted avg manufacturer price $0.2120 · Aug 1, 2026100% of what pharmacies pay — higher than 10% of drugs with this benchmark

Medicare Part D

All Part D pricing →
ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$0.4777per unit
middle half $0.3408$0.5896 · 5,496 plans · Apr 1, 2026
Est. net of rebates
≈ $0.4777
generic — rebates are minimal, so net ≈ gross
Coverage & restrictions
100%of plans cover it
tier 2 · prior auth 2% · step therapy 0% · qty limit 96%

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 1 quarter since 2024.

NADAC price per unit

$0$0.2$0.4$0.6Nov 2013Sep 2026$0.3809
155 price points · per EA · dashed = manufacturer avg (WAMP)Source: CMS NADAC

Estimated fill cost

#30 count
$11.43
#90 count
$34.28

Estimates: latest NADAC unit price × quantity. Pharmacy acquisition cost only — excludes dispensing fees, markup, and insurance terms.

Medicaid spend (2025)

$851,024
28,306 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

0Low risk

Nothing here is signaling trouble: several manufacturers, no current shortage, no recent serious recalls, stable pricing. In drug supply, boring is the good outcome.

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for acetaminophen and codeine phosphate (oral solid) in the next 90 days

sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Is this a "specialty" drug?

There's no legal definition — it meets 1 of 6 public criteria. Why that matters →

  • Part D specialty tier · median tier 2 across plans
  • Costs ≥ $950/fill
  • Biologic (BLA)
  • Injectable / infused
  • Orphan-drug exclusivity
  • REMS program · Opioid Analgesic REMS Shared System REMS

Regulatory

Application
ANDA040419
TE code
AA
Approval date
May 31, 2001
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of acetaminophen and codeine phosphate (Tablet)

LabelerStrengthFirst seenLast seen
Advanced Rx of Tennessee, LLCACETAMINOPHEN 300 mg/1; CODEINE PHOSPHATE 60 mg/1Jul 15, 2026Sep 3, 2026
Advanced Rx of Tennessee, LLCACETAMINOPHEN 300 mg/1; CODEINE PHOSPHATE 30 mg/1Jul 15, 2026Sep 3, 2026
Bryant Ranch PrepackACETAMINOPHEN 300 mg/1; CODEINE PHOSPHATE 30 mg/1Jul 15, 2026Sep 3, 2026
Bryant Ranch PrepackACETAMINOPHEN 300 mg/1; CODEINE PHOSPHATE 60 mg/1Jul 15, 2026Sep 3, 2026
NuCare Pharmaceuticals, Inc.ACETAMINOPHEN 300 mg/1; CODEINE PHOSPHATE 30 mg/1Jul 15, 2026Sep 3, 2026
NuCare Pharmaceuticals,Inc.ACETAMINOPHEN 300 mg/1; CODEINE PHOSPHATE 30 mg/1Jul 15, 2026Sep 3, 2026
Preferred Pharmaceuticals Inc.ACETAMINOPHEN 300 mg/1; CODEINE PHOSPHATE 60 mg/1Jul 15, 2026Sep 3, 2026
Proficient Rx LPACETAMINOPHEN 300 mg/1; CODEINE PHOSPHATE 30 mg/1Jul 15, 2026Sep 3, 2026
Remedyrepack Inc.ACETAMINOPHEN 300 mg/1; CODEINE PHOSPHATE 30 mg/1Jul 15, 2026Sep 3, 2026
A-S Medication SolutionsACETAMINOPHEN 300 mg/1; CODEINE PHOSPHATE 60 mg/1Jul 15, 2026Sep 2, 2026
Aphena Pharma Solutions - Tennessee, LLCACETAMINOPHEN 300 mg/1; CODEINE PHOSPHATE 30 mg/1Jul 15, 2026Sep 2, 2026
Aphena Pharma Solutions - Tennessee, LLCACETAMINOPHEN 300 mg/1; CODEINE PHOSPHATE 60 mg/1Jul 15, 2026Sep 2, 2026
Asclemed USA, Inc.ACETAMINOPHEN 300 mg/1; CODEINE PHOSPHATE 30 mg/1Jul 15, 2026Sep 2, 2026
Aurolife Pharma, LLCACETAMINOPHEN 300 mg/1; CODEINE PHOSPHATE 30 mg/1Jul 15, 2026Sep 2, 2026
Aurolife Pharma, LLCACETAMINOPHEN 300 mg/1; CODEINE PHOSPHATE 15 mg/1Jul 15, 2026Sep 2, 2026
Aurolife Pharma, LLCACETAMINOPHEN 300 mg/1; CODEINE PHOSPHATE 60 mg/1Jul 15, 2026Sep 2, 2026
Clinical Solutions Wholesale, LLCACETAMINOPHEN 300 mg/1; CODEINE PHOSPHATE 60 mg/1Jul 15, 2026Sep 2, 2026
Clinical Solutions Wholesale, LLCACETAMINOPHEN 300 mg/1; CODEINE PHOSPHATE 30 mg/1Jul 15, 2026Sep 2, 2026
Direct_RxACETAMINOPHEN 300 mg/1; CODEINE PHOSPHATE 60 mg/1Jul 15, 2026Sep 2, 2026
Elite Laboratories, Inc.ACETAMINOPHEN 300 mg/1; CODEINE PHOSPHATE 15 mg/1Jul 15, 2026Sep 2, 2026
Elite Laboratories, Inc.ACETAMINOPHEN 300 mg/1; CODEINE PHOSPHATE 30 mg/1Jul 15, 2026Sep 2, 2026
Elite Laboratories, Inc.ACETAMINOPHEN 300 mg/1; CODEINE PHOSPHATE 60 mg/1Jul 15, 2026Sep 2, 2026
Eywa Pharma IncACETAMINOPHEN 300 mg/1; CODEINE PHOSPHATE 15 mg/1Jul 15, 2026Sep 2, 2026
Eywa Pharma IncACETAMINOPHEN 300 mg/1; CODEINE PHOSPHATE 30 mg/1Jul 15, 2026Sep 2, 2026
Eywa Pharma IncACETAMINOPHEN 300 mg/1; CODEINE PHOSPHATE 60 mg/1Jul 15, 2026Sep 2, 2026
NuCare Pharmaceuticals,Inc.ACETAMINOPHEN 300 mg/1; CODEINE PHOSPHATE 60 mg/1Jul 15, 2026Sep 2, 2026
Preferred Pharmaceuticals Inc.ACETAMINOPHEN 300 mg/1; CODEINE PHOSPHATE 30 mg/1Jul 15, 2026Sep 2, 2026
Quality Care Products, LLCACETAMINOPHEN 300 mg/1; CODEINE PHOSPHATE 30 mg/1Jul 15, 2026Sep 2, 2026
Redpharm DrugACETAMINOPHEN 300 mg/1; CODEINE PHOSPHATE 30 mg/1Jul 15, 2026Sep 2, 2026
Remedyrepack Inc.ACETAMINOPHEN 300 mg/1; CODEINE PHOSPHATE 60 mg/1Jul 15, 2026Sep 2, 2026
SpecGx LLCACETAMINOPHEN 300 mg/1; CODEINE PHOSPHATE 30 mg/1Jul 15, 2026Sep 2, 2026
SpecGx LLCACETAMINOPHEN 300 mg/1; CODEINE PHOSPHATE 60 mg/1Jul 15, 2026Sep 2, 2026
SpecGx LLCACETAMINOPHEN 300 mg/1; CODEINE PHOSPHATE 15 mg/1Jul 15, 2026Sep 2, 2026
St. Mary's Medical Park PharmacyACETAMINOPHEN 300 mg/1; CODEINE PHOSPHATE 30 mg/1Jul 15, 2026Sep 2, 2026
St. Mary's Medical Park PharmacyACETAMINOPHEN 300 mg/1; CODEINE PHOSPHATE 30 mg/1Jul 15, 2026Sep 2, 2026
Strides Pharma Science LimitedACETAMINOPHEN 300 mg/1; CODEINE PHOSPHATE 30 mg/1Jul 15, 2026Sep 2, 2026
Strides Pharma Science LimitedACETAMINOPHEN 300 mg/1; CODEINE PHOSPHATE 15 mg/1Jul 15, 2026Sep 2, 2026
Strides Pharma Science LimitedACETAMINOPHEN 300 mg/1; CODEINE PHOSPHATE 60 mg/1Jul 15, 2026Sep 2, 2026
Unit Dose Solutions, Inc.ACETAMINOPHEN 300 mg/1; CODEINE PHOSPHATE 30 mg/1Jul 15, 2026Sep 2, 2026
A-S Medication SolutionsACETAMINOPHEN 300 mg/1; CODEINE PHOSPHATE 30 mg/1Jul 15, 2026Aug 31, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Acetaminophen And Codeine Phosphate — NDC 00406-0485-01," retrieved September 3, 2026, https://drugdashboards.com/drug/00406048501.

Free to cite with attribution — see how the data is put together.