Methadone Hydrochloride · METHADONE HYDROCHLORIDE 10 mg/5mL · Solution · Oral · SpecGx LLC
NDC 00406-6221-05 · 500 mL in 1 BOTTLE · ANDA · View full market →
5 companies supply this market — a reasonable cushion if one runs into trouble. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
Matched to CMS's representative package for this drug (NDC 00054-3556-63) — same generic, strength, and dosage form. CMS prices one NDC per drug concept, not every package.
Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.
Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.
*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.
Manufacturer list price as filed — not what pharmacies actually pay after discounts.
Some pressure is visible, but not much — here’s everything the score found to count.
The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026
sole-source market · price up 3% YoY
For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.
Backtested statistical model over the whole market, not this package alone. Model details →
Establishments this product's FDA label declares, located via FDA registration data. How we built this →
There's no legal definition — it meets 1 of 6 public criteria. Why that matters →
No FDA shortage reports for this drug or its presentations.
No enforcement reports list this package NDC.
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| Precision Dose, Inc. | METHADONE HYDROCHLORIDE 5 mg/5mL | Jul 15, 2026 | Sep 3, 2026 |
| American Health Packaging | METHADONE HYDROCHLORIDE 5 mg/5mL | Jul 15, 2026 | Sep 2, 2026 |
| Hikma Pharmaceuticals USA Inc. | METHADONE HYDROCHLORIDE 10 mg/5mL | Jul 15, 2026 | Sep 2, 2026 |
| Hikma Pharmaceuticals USA Inc. | METHADONE HYDROCHLORIDE 5 mg/5mL | Jul 15, 2026 | Sep 2, 2026 |
| SpecGx LLC | METHADONE HYDROCHLORIDE 10 mg/5mL | Jul 15, 2026 | Sep 2, 2026 |
| SpecGx LLC | METHADONE HYDROCHLORIDE 5 mg/5mL | Jul 15, 2026 | Sep 2, 2026 |
| VistaPharm, LLC | METHADONE HYDROCHLORIDE 5 mg/5mL | Jul 15, 2026 | Sep 2, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
DrugDashboards, "Methadone Hydrochloride — NDC 00406-6221-05," retrieved September 3, 2026, https://drugdashboards.com/drug/00406622105.
Free to cite with attribution — see how the data is put together.