DrugDashboards

Lidocaine Hydrochloride and Epinephrine

LIDOCAINE HYDROCHLORIDE and EPINEPHRINE · LIDOCAINE HYDROCHLORIDE 10 mg/mL; EPINEPHRINE 10 ug/mL · Injection, Solution · Infiltration; Perineural · Hospira, Inc.

NDC 00409-3178-01 · 25 VIAL, MULTI-DOSE in 1 TRAY / 20 mL in 1 VIAL, MULTI-DOSE · ANDA · View full market →

The short version

6 companies supply this market — a reasonable cushion if one runs into trouble. The price has held steady around $0.0883 per unit over the past year. It is in shortage right now — FDA lists the reason as “other”.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

Medicare Part D

No Medicare Part D plan in CMS's quarterly files lists this product. That usually means it is discontinued, a repackager's listing, or a product no plan has added to its formulary.

How Part D pricing works →

NADAC price per unit

$0$0.05$0.1Jul 2014Apr 2015$0.0883
3 price points · per · last surveyed Invalid DateSource: CMS NADAC

Estimated fill cost

WAC per package, as filed
$59.39
Reported to Texas DSHS · 2026 annual filing · Pfizer Inc.

Manufacturer list price as filed — not what pharmacies actually pay after discounts.

Medicaid spend (2025)

$131,915
8,543 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

Not scored — fragility is computed for NADAC-priced NDCs.

90-day shortage risk (model v2)

0.4%chance of a new FDA shortage posting for lidocaine hydrochloride and epinephrine (injectable) in the next 90 days

sterile injectable · sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is 3× that.

Backtested statistical model over the whole market, not this package alone. Model details →

Is this a "specialty" drug?

There's no legal definition — it meets 1 of 6 public criteria. Why that matters →

  • Part D specialty tier
  • Costs ≥ $950/fill
  • Biologic (BLA)
  • Injectable / infused
  • Orphan-drug exclusivity
  • REMS program

Regulatory

Application
ANDA089644
TE code
AP
Approval date
Jun 21, 1988
Patents / exclusivity
None on file

Shortage history

  • In shortage now — Lidocaine Hydrochloride And Epinephrine, Injection, 1 g/50 mL (2%; 1:100,000) (NDC 0409-3182-03)Feb 22, 2012
    Other
    month 175 — 9× the typical 20-month injectable shortage
  • In shortage now — Lidocaine Hydrochloride And Epinephrine, Injection, 2.5 g/50 mL (0.5%; 1:200,000) (NDC 0409-3177-01)Feb 22, 2012
    Other
    month 175 — 9× the typical 20-month injectable shortage
  • In shortage now — Lidocaine Hydrochloride And Epinephrine, Injection, 200 mg/20 mL (1%; 1:100,000) (NDC 0409-3178-01)Feb 22, 2012
    Other
    month 175 — 9× the typical 20-month injectable shortage
  • In shortage now — Lidocaine Hydrochloride And Epinephrine, Injection, 300 mg/30 mL (1%; 1:100,000) (NDC 0409-3178-02)Feb 22, 2012
    Other
    month 175 — 9× the typical 20-month injectable shortage
  • In shortage now — Lidocaine Hydrochloride And Epinephrine, Injection, 400 mg/20 mL (2%; 1:100,000) (NDC 0409-3182-01)Feb 22, 2012
    Other
    month 175 — 9× the typical 20-month injectable shortage
  • In shortage now — Lidocaine Hydrochloride And Epinephrine, Injection, 400 mg/20 mL (2%; 1:200,000) (NDC 0409-3183-01)Feb 22, 2012
    month 175 — 9× the typical 20-month injectable shortage
  • In shortage now — Lidocaine Hydrochloride And Epinephrine, Injection, 450 mg/30 mL (1.5%; 1:200,000) (NDC 0409-3181-01)Feb 22, 2012
    month 175 — 9× the typical 20-month injectable shortage
  • In shortage now — Lidocaine Hydrochloride And Epinephrine, Injection, 500 mg/50 mL (1%; 1:100,000) (NDC 0409-3178-03)Feb 22, 2012
    month 175 — 9× the typical 20-month injectable shortage
  • In shortage now — Lidocaine Hydrochloride and Epinephrine, Injection, 600 mg/30 mL (2%; 1:100,000) (NDC 0409-3182-02)Feb 22, 2012
    Other
    month 175 — 9× the typical 20-month injectable shortage
  • In shortage now — Lidocaine Hydrochloride And Epinephrine, Injection, 75 mg/5 mL (1.5%; 1:200,000) (NDC 0409-1209-01)Feb 22, 2012
    Other
    month 175 — 9× the typical 20-month injectable shortage

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of LIDOCAINE HYDROCHLORIDE and EPINEPHRINE (Injection, Solution)

LabelerStrengthFirst seenLast seen
Henry Schein, Inc.LIDOCAINE HYDROCHLORIDE 20 mg/mL; EPINEPHRINE 10 ug/mLAug 26, 2026Sep 3, 2026
Hospira, Inc.LIDOCAINE HYDROCHLORIDE 15 mg/mL; EPINEPHRINE 5 ug/mLAug 26, 2026Sep 3, 2026
Hospira, Inc.LIDOCAINE HYDROCHLORIDE 20 mg/mL; EPINEPHRINE 10 ug/mLAug 26, 2026Sep 3, 2026
Septodont, Inc.LIDOCAINE HYDROCHLORIDE 20 mg/mL; EPINEPHRINE BITARTRATE .02 mg/mLAug 26, 2026Sep 3, 2026
Septodont, Inc.LIDOCAINE HYDROCHLORIDE 20 mg/mL; EPINEPHRINE BITARTRATE .01 mg/mLAug 26, 2026Sep 3, 2026
Cardinal Health 107, LLCLIDOCAINE HYDROCHLORIDE 10 mg/mL; EPINEPHRINE 10 ug/mLAug 26, 2026Sep 2, 2026
Henry Schein, Inc.LIDOCAINE HYDROCHLORIDE ANHYDROUS 20 mg/mL; EPINEPHRINE BITARTRATE .01 mg/mLAug 26, 2026Sep 2, 2026
Henry Schein, Inc.LIDOCAINE HYDROCHLORIDE ANHYDROUS 10 mg/mL; EPINEPHRINE BITARTRATE .01 mg/mLAug 26, 2026Sep 2, 2026
Henry Schein, Inc.LIDOCAINE HYDROCHLORIDE 5 mg/mL; EPINEPHRINE 5 ug/mLAug 26, 2026Sep 2, 2026
Henry Schein, Inc.LIDOCAINE HYDROCHLORIDE ANHYDROUS 20 mg/mL; EPINEPHRINE BITARTRATE .005 mg/mLAug 26, 2026Sep 2, 2026
Hospira, Inc.LIDOCAINE HYDROCHLORIDE 5 mg/mL; EPINEPHRINE 5 ug/mLAug 26, 2026Sep 2, 2026
Hospira, Inc.LIDOCAINE HYDROCHLORIDE 20 mg/mL; EPINEPHRINE 5 ug/mLAug 26, 2026Sep 2, 2026
ProPharma DistributionLIDOCAINE HYDROCHLORIDE 20 mg/mL; EPINEPHRINE 10 ug/mLAug 26, 2026Sep 2, 2026
Sportpharm LLCLIDOCAINE HYDROCHLORIDE 10 mg/mL; EPINEPHRINE 10 ug/mLAug 26, 2026Sep 2, 2026
Hospira, Inc.LIDOCAINE HYDROCHLORIDE 10 mg/mL; EPINEPHRINE 10 ug/mLAug 26, 2026Aug 31, 2026
Henry Schein, Inc.LIDOCAINE HYDROCHLORIDE 10 mg/mL; EPINEPHRINE 10 ug/mLAug 26, 2026Aug 28, 2026
Hospira, Inc.LIDOCAINE HYDROCHLORIDE 10 ug/mL; EPINEPHRINE 10 mg/mLJul 22, 2026Aug 22, 2026
Hospira, Inc.LIDOCAINE HYDROCHLORIDE 5 ug/mL; EPINEPHRINE 15 mg/mLJul 22, 2026Aug 22, 2026
Hospira, Inc.LIDOCAINE HYDROCHLORIDE 10 ug/mL; EPINEPHRINE 20 mg/mLJul 22, 2026Aug 22, 2026
Septodont, Inc.LIDOCAINE HYDROCHLORIDE .01 mg/mL; EPINEPHRINE BITARTRATE 20 mg/mLJul 22, 2026Aug 22, 2026
Henry Schein, Inc.LIDOCAINE HYDROCHLORIDE 10 ug/mL; EPINEPHRINE 20 mg/mLJul 22, 2026Aug 21, 2026
Henry Schein, Inc.LIDOCAINE HYDROCHLORIDE 10 ug/mL; EPINEPHRINE 10 mg/mLJul 22, 2026Aug 21, 2026
Cardinal Health 107, LLCLIDOCAINE HYDROCHLORIDE 10 ug/mL; EPINEPHRINE 10 mg/mLJul 22, 2026Aug 19, 2026
Henry Schein, Inc.LIDOCAINE HYDROCHLORIDE ANHYDROUS .005 mg/mL; EPINEPHRINE BITARTRATE 20 mg/mLJul 22, 2026Aug 19, 2026
Henry Schein, Inc.LIDOCAINE HYDROCHLORIDE 5 ug/mL; EPINEPHRINE 5 mg/mLJul 22, 2026Aug 19, 2026
Henry Schein, Inc.LIDOCAINE HYDROCHLORIDE ANHYDROUS .01 mg/mL; EPINEPHRINE BITARTRATE 10 mg/mLJul 22, 2026Aug 19, 2026
Henry Schein, Inc.LIDOCAINE HYDROCHLORIDE ANHYDROUS .01 mg/mL; EPINEPHRINE BITARTRATE 20 mg/mLJul 22, 2026Aug 19, 2026
Hospira, Inc.LIDOCAINE HYDROCHLORIDE 5 ug/mL; EPINEPHRINE 20 mg/mLJul 22, 2026Aug 19, 2026
Hospira, Inc.LIDOCAINE HYDROCHLORIDE 5 ug/mL; EPINEPHRINE 5 mg/mLJul 22, 2026Aug 19, 2026
ProPharma DistributionLIDOCAINE HYDROCHLORIDE 10 ug/mL; EPINEPHRINE 20 mg/mLJul 22, 2026Aug 19, 2026
Septodont, Inc.LIDOCAINE HYDROCHLORIDE .02 mg/mL; EPINEPHRINE BITARTRATE 20 mg/mLJul 22, 2026Aug 19, 2026
Sportpharm LLCLIDOCAINE HYDROCHLORIDE 10 ug/mL; EPINEPHRINE 10 mg/mLJul 22, 2026Aug 19, 2026
Hospira, Inc.EPINEPHRINE 10 ug/mL; LIDOCAINE HYDROCHLORIDE 10 mg/mLJul 15, 2026Jul 19, 2026
Septodont, Inc.EPINEPHRINE BITARTRATE .02 mg/mL; LIDOCAINE HYDROCHLORIDE 20 mg/mLJul 15, 2026Jul 19, 2026
Henry Schein, Inc.EPINEPHRINE 10 ug/mL; LIDOCAINE HYDROCHLORIDE 10 mg/mLJul 15, 2026Jul 18, 2026
Henry Schein, Inc.EPINEPHRINE 10 ug/mL; LIDOCAINE HYDROCHLORIDE 20 mg/mLJul 15, 2026Jul 18, 2026
Septodont, Inc.EPINEPHRINE BITARTRATE .01 mg/mL; LIDOCAINE HYDROCHLORIDE 20 mg/mLJul 15, 2026Jul 18, 2026
Cardinal Health 107, LLCEPINEPHRINE 10 ug/mL; LIDOCAINE HYDROCHLORIDE 10 mg/mLJul 15, 2026Jul 15, 2026
Henry Schein, Inc.EPINEPHRINE BITARTRATE .005 mg/mL; LIDOCAINE HYDROCHLORIDE ANHYDROUS 20 mg/mLJul 15, 2026Jul 15, 2026
Henry Schein, Inc.EPINEPHRINE 5 ug/mL; LIDOCAINE HYDROCHLORIDE 5 mg/mLJul 15, 2026Jul 15, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Lidocaine Hydrochloride and Epinephrine — NDC 00409-3178-01," retrieved September 3, 2026, https://drugdashboards.com/drug/00409317801.

Free to cite with attribution — see how the data is put together.