DrugDashboards

Savella

milnacipran hydrochloride · MILNACIPRAN HYDROCHLORIDE 12.5 mg/1 · Tablet, Film Coated · Oral · Allergan, Inc.

NDC 00456-1512-60 · 60 TABLET, FILM COATED in 1 BOTTLE · NDA · View full market →

The short version

4 companies supply this market — a reasonable cushion if one runs into trouble. The brand price has held steady around $8.17 per unit over the past year. Generic versions run $2.87 per unit2.8× cheaper. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$8.17per EAinvoice-surveyed acquisition cost · Aug 19, 2026
  • Part D plans paid (avg)$7.96per dosage unitgross, before rebates — matched by drug name · 2024
  • Part D point of sale (median)$8.55per unitnegotiated price across 1,761 plans — before rebates · Apr 1, 2026
  • Federal ceiling (Big4)$6.18per unitAbbvie US LLC · Jan 1, 202676% of what pharmacies pay — a deeper discount than 67% of drugs with this benchmark
  • Medicaid generic ceiling (FUL)$4.01per TABweighted avg manufacturer price $2.2934 · Aug 1, 202649% of what pharmacies pay — a deeper discount than 95% of drugs with this benchmark

Medicare Part D

All Part D pricing →
ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$8.55per unit
middle half $8.09$8.73 · 1,761 plans · Apr 1, 2026
Est. net of rebates
$5.13–$6.41
brand drug — est. 25-40% rebate off the price at left
Coverage & restrictions
32%of plans cover it
tier 3 · prior auth 12% · step therapy 2% · qty limit 43%

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.

NADAC price per unit

$0$5.00$10.00Nov 2013Sep 2026$8.17
45 price points · per EA · dashed = manufacturer avg (WAMP)Source: CMS NADAC

Estimated fill cost

#30 count
$244.97
#90 count
$734.91

Estimates: latest NADAC unit price × quantity. Pharmacy acquisition cost only — excludes dispensing fees, markup, and insurance terms.

Medicaid spend (2025)

$1.1M
2,192 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

5Low risk

Some pressure is visible, but not much — here’s everything the score found to count.

  • 4 active manufacturers+5

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for milnacipran hydrochloride (oral solid) in the next 90 days

sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Regulatory

Application
NDA022256
TE code
AB
Approval date
Jan 14, 2009
Patents / exclusivity
4 patents, 0 exclusivities
TypeNumber / codeExpires
patent7994220Sep 19, 2029
patent7994220Sep 19, 2029
patent7994220Sep 19, 2029
patent7994220Sep 19, 2029

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of milnacipran hydrochloride (Tablet, Film Coated)

LabelerStrengthFirst seenLast seen
Allergan, Inc.MILNACIPRAN HYDROCHLORIDE 50 mg/1Jul 15, 2026Sep 3, 2026
Allergan, Inc.MILNACIPRAN HYDROCHLORIDE 12.5 mg/1Jul 15, 2026Sep 3, 2026
Allergan, Inc.MILNACIPRAN HYDROCHLORIDE 100 mg/1Jul 15, 2026Sep 3, 2026
Camber Pharmaceuticals, Inc.MILNACIPRAN HYDROCHLORIDE 100 mg/1Jul 15, 2026Sep 2, 2026
Camber Pharmaceuticals, Inc.MILNACIPRAN HYDROCHLORIDE 25 mg/1Jul 15, 2026Sep 2, 2026
Camber Pharmaceuticals, Inc.MILNACIPRAN HYDROCHLORIDE 50 mg/1Jul 15, 2026Sep 2, 2026
Camber Pharmaceuticals, Inc.MILNACIPRAN HYDROCHLORIDE 12.5 mg/1Jul 15, 2026Sep 2, 2026
Cardinal Health 107, LLCMILNACIPRAN HYDROCHLORIDE 50 mg/1Jul 15, 2026Sep 2, 2026
Glenmark Pharmaceuticals Inc., USAMILNACIPRAN HYDROCHLORIDE 50 mg/1Jul 15, 2026Sep 2, 2026
Glenmark Pharmaceuticals Inc., USAMILNACIPRAN HYDROCHLORIDE 100 mg/1Jul 15, 2026Sep 2, 2026
Glenmark Pharmaceuticals Inc., USAMILNACIPRAN HYDROCHLORIDE 12.5 mg/1Jul 15, 2026Sep 2, 2026
Glenmark Pharmaceuticals Inc., USAMILNACIPRAN HYDROCHLORIDE 25 mg/1Jul 15, 2026Sep 2, 2026
Allergan, Inc.MILNACIPRAN HYDROCHLORIDE 25 mg/1Jul 15, 2026Aug 31, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Savella — NDC 00456-1512-60," retrieved September 3, 2026, https://drugdashboards.com/drug/00456151260.

Free to cite with attribution — see how the data is put together.