memantine hydrochloride
memantine hydrochloride · MEMANTINE HYDROCHLORIDE 21 mg/1 · Capsule, Extended Release · Allergan, Inc.
NDC 00456-3422-00 · 1 BAG in 1 DRUM / 60000 CAPSULE, EXTENDED RELEASE in 1 BAG · DRUG FOR FURTHER PROCESSING · View full market →
Bulk ingredient — not a finished product
This NDC is a raw material (drug for further processing) sold to drug manufacturers or compounders, not a product pharmacies dispense. Retail pricing, TE codes, fragility scores, and shortage reports don't apply to bulk listings — those attach to finished products made from this ingredient.
Medicare Part D
All Part D pricing →Matched to CMS's representative package for this drug (NDC 68382-0548-06) — same generic, strength, and dosage form. CMS prices one NDC per drug concept, not every package.
ⓘ How this was built
- CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.
Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.
*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.
NADAC price per unit
No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.
Supply fragility
Not scored — fragility is computed for NADAC-priced NDCs.
90-day shortage risk (model v2)
OAI inspection at a producing facility (24 months) · sole-source market · 1 Class I/II recall(s) in 12 months
For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.
Backtested statistical model over the whole market, not this package alone. Model details →
Regulatory
- Application
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- TE code
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- Approval date
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- Patents / exclusivity
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Shortage history
No FDA shortage reports for this drug or its presentations.
Recalls (this NDC)
No enforcement reports list this package NDC.
Manufacturers of memantine hydrochloride (Capsule, Extended Release)
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| NCS HealthCare of KY, LLC dba Vangard Labs | MEMANTINE HYDROCHLORIDE 28 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| Amneal Pharmaceuticals LLC | MEMANTINE HYDROCHLORIDE 21 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Amneal Pharmaceuticals LLC | MEMANTINE HYDROCHLORIDE 28 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Amneal Pharmaceuticals LLC | MEMANTINE HYDROCHLORIDE 14 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Amneal Pharmaceuticals LLC | MEMANTINE HYDROCHLORIDE 7 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Aurobindo Pharma Limited | MEMANTINE HYDROCHLORIDE 14 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Aurobindo Pharma Limited | MEMANTINE HYDROCHLORIDE 21 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Aurobindo Pharma Limited | MEMANTINE HYDROCHLORIDE 7 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Aurobindo Pharma Limited | MEMANTINE HYDROCHLORIDE 28 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Lupin Pharmaceuticals, Inc. | MEMANTINE HYDROCHLORIDE 21 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Lupin Pharmaceuticals, Inc. | MEMANTINE HYDROCHLORIDE 7 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Lupin Pharmaceuticals, Inc. | MEMANTINE HYDROCHLORIDE 28 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Lupin Pharmaceuticals, Inc. | MEMANTINE HYDROCHLORIDE 14 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Macleods Pharmaceuticals Limited | MEMANTINE HYDROCHLORIDE 7 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Macleods Pharmaceuticals Limited | MEMANTINE HYDROCHLORIDE 14 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Macleods Pharmaceuticals Limited | MEMANTINE HYDROCHLORIDE 21 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Macleods Pharmaceuticals Limited | MEMANTINE HYDROCHLORIDE 28 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Major Pharmaceuticals | MEMANTINE HYDROCHLORIDE 7 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Major Pharmaceuticals | MEMANTINE HYDROCHLORIDE 28 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Slate Run Pharmaceuticals, LLC | MEMANTINE HYDROCHLORIDE 28 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Slate Run Pharmaceuticals, LLC | MEMANTINE HYDROCHLORIDE 21 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Slate Run Pharmaceuticals, LLC | MEMANTINE HYDROCHLORIDE 14 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Slate Run Pharmaceuticals, LLC | MEMANTINE HYDROCHLORIDE 7 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Vitruvias Therapeutics, Inc. | MEMANTINE HYDROCHLORIDE 28 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Vitruvias Therapeutics, Inc. | MEMANTINE HYDROCHLORIDE 7 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Vitruvias Therapeutics, Inc. | MEMANTINE HYDROCHLORIDE 21 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Vitruvias Therapeutics, Inc. | MEMANTINE HYDROCHLORIDE 14 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Zydus Lifesciences Limited | MEMANTINE HYDROCHLORIDE 21 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Zydus Lifesciences Limited | MEMANTINE HYDROCHLORIDE 14 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Zydus Lifesciences Limited | MEMANTINE HYDROCHLORIDE 28 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Zydus Lifesciences Limited | MEMANTINE HYDROCHLORIDE 7 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Zydus Pharmaceuticals USA Inc. | MEMANTINE HYDROCHLORIDE 14 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Zydus Pharmaceuticals USA Inc. | MEMANTINE HYDROCHLORIDE 7 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Zydus Pharmaceuticals USA Inc. | MEMANTINE HYDROCHLORIDE 21 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Zydus Pharmaceuticals USA Inc. | MEMANTINE HYDROCHLORIDE 28 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Allergan, Inc. | MEMANTINE HYDROCHLORIDE 28 mg/1 | Jul 15, 2026 | Aug 12, 2026 |
| Allergan, Inc. | MEMANTINE HYDROCHLORIDE 21 mg/1 | Jul 15, 2026 | Aug 12, 2026 |
| Allergan, Inc. | MEMANTINE HYDROCHLORIDE 14 mg/1 | Jul 15, 2026 | Aug 12, 2026 |
| Allergan, Inc. | MEMANTINE HYDROCHLORIDE 7 mg/1 | Jul 15, 2026 | Aug 12, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
Cite this page
DrugDashboards, "memantine hydrochloride — NDC 00456-3422-00," retrieved September 3, 2026, https://drugdashboards.com/drug/00456342200.
Free to cite with attribution — see how the data is put together.