DrugDashboards

Astagraf Xl

tacrolimus extended-release capsules · TACROLIMUS 1 mg/1 · Capsule, Coated, Extended Release · Oral · Astellas Pharma US, Inc.

NDC 00469-0677-73 · 1 BOTTLE in 1 CARTON / 30 CAPSULE, COATED, EXTENDED RELEASE in 1 BOTTLE · NDA · View full market →

The short version

Just 2 companies supply this market — thin enough that a single exit would be felt immediately. The price has held steady around $5.71 per unit over the past year. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$5.71per EAinvoice-surveyed acquisition cost · Aug 19, 2026
  • Medicare Part B pays (ASP+6%)$0.6010per billing unit (0.1 MG)HCPCS J7508 · Jul 1, 2026
  • Part D plans paid (avg)$9.05per dosage unitgross, before rebates — matched by drug name · 2024
  • Part D point of sale (median)$6.03per unitnegotiated price across 2,878 plans — before rebates · Apr 1, 2026
  • Federal contracts pay (FSS)$3.96per unitAstellas Pharma U.S., Inc. · Jan 1, 202669% of what pharmacies pay — a deeper discount than 76% of drugs with this benchmark

Medicare Part D

All Part D pricing →
ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$6.03per unit
middle half $5.86$6.21 · 2,878 plans · Apr 1, 2026
Est. net of rebates
$3.62–$4.52
brand drug — est. 25-40% rebate off the price at left
Coverage & restrictions
52%of plans cover it
tier 4 · prior auth 100% · step therapy 1% · qty limit 0%

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.

NADAC price per unit

$0$2.00$4.00$6.00Jan 2020Sep 2026$5.71
22 price points · per EASource: CMS NADAC

Estimated fill cost

#30 count
$171.27
#90 count
$513.82

Estimates: latest NADAC unit price × quantity. Pharmacy acquisition cost only — excludes dispensing fees, markup, and insurance terms.

Medicare Part B (ASP)

Payment limit per 0.1 MG
$0.601
HCPCS J7508 · Jul 1, 2026 quarter · typically ASP + 6%

Medicaid spend (2025)

$660,694
1,465 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

20Low risk

Some pressure is visible, but not much — here’s everything the score found to count.

  • 2 active manufacturers+20

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for tacrolimus (oral solid) in the next 90 days

OAI inspection at a producing facility (24 months) · sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Where it's made

Establishments this product's FDA label declares, located via FDA registration data. How we built this →

Regulatory

Application
NDA204096
TE code
AB
Approval date
Jul 19, 2013
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

  • Class I · OngoingDec 23, 2024
    Astellas Pharma US Inc.Failed Tablet/Capsule Specifications: Bottles shipped to the USA may contain empty capsules

Manufacturers of tacrolimus extended-release capsules (Capsule, Coated, Extended Release)

LabelerStrengthFirst seenLast seen
Astellas Pharma US, Inc.TACROLIMUS .5 mg/1Jul 15, 2026Sep 2, 2026
Astellas Pharma US, Inc.TACROLIMUS 1 mg/1Jul 15, 2026Sep 2, 2026
Astellas Pharma US, Inc.TACROLIMUS 5 mg/1Jul 15, 2026Sep 2, 2026
Chengdu Suncadia Medicine Co., Ltd.TACROLIMUS .5 mg/1Jul 15, 2026Sep 2, 2026
Chengdu Suncadia Medicine Co., Ltd.TACROLIMUS 1 mg/1Jul 15, 2026Sep 2, 2026
Chengdu Suncadia Medicine Co., Ltd.TACROLIMUS 5 mg/1Jul 15, 2026Sep 2, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Astagraf Xl — NDC 00469-0677-73," retrieved September 3, 2026, https://drugdashboards.com/drug/00469067773.

Free to cite with attribution — see how the data is put together.