DrugDashboards

Hydromet

hydrocodone bitartrate and homatropine methylbromide · HYDROCODONE BITARTRATE 5 mg/5mL; HOMATROPINE METHYLBROMIDE 1.5 mg/5mL · Solution · Oral · Actavis Pharma, Inc.

NDC 00472-1030-16 · 473 mL in 1 BOTTLE · ANDA · View full market →

The short version

Just 3 companies supply this market — thin enough that a single exit would be felt immediately. The price has held steady around $0.1031 per mL over the past year. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$0.1031per MLinvoice-surveyed acquisition cost · Aug 19, 2026
  • Part D plans paid (avg)$0.1289per dosage unitgross, before rebates — matched by drug name · 2024
  • Medicaid generic ceiling (FUL)$0.0980per MLweighted avg manufacturer price $0.0508 · Feb 1, 202695% of what pharmacies pay — a deeper discount than 95% of drugs with this benchmark

Medicare Part D

No Medicare Part D plan in CMS's quarterly files lists this product. That usually means it is discontinued, a repackager's listing, or a product no plan has added to its formulary.

How Part D pricing works →

NADAC price per unit

$0$0.1$0.2$0.3Nov 2013Sep 2026$0.1031
155 price points · per ML · dashed = manufacturer avg (WAMP)Source: CMS NADAC

Estimated fill cost

WAC per package, as filed
$69.95
Reported to Texas DSHS · 2026 annual filing · Actavis Pharma, Inc.

Manufacturer list price as filed — not what pharmacies actually pay after discounts.

Medicaid spend (2025)

$16,734
1,108 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

20Low risk

Some pressure is visible, but not much — here’s everything the score found to count.

  • 3 active manufacturers+10
  • manufacturer plans to discontinue+10

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.2%chance of a new FDA shortage posting for hydrocodone bitartrate and homatropine methylbromide (other) in the next 90 days

OAI inspection at a producing facility (24 months) · sole-source market · price up 8% YoY

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Is this a "specialty" drug?

There's no legal definition — it meets 1 of 6 public criteria. Why that matters →

  • Part D specialty tier
  • Costs ≥ $950/fill · avg $16.10 per prescription
  • Biologic (BLA)
  • Injectable / infused
  • Orphan-drug exclusivity
  • REMS program · Opioid Analgesic REMS Shared System REMS

Regulatory

Application
ANDA088017
TE code
AA
Approval date
Jul 5, 1983
Patents / exclusivity
None on file

Shortage history

  • Planned discontinuation Hydromet, Syrup, 1.5 mg/5 mL; 5 mg/5 mL (NDC 0472-1030-16)Sep 11, 2025

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of hydrocodone bitartrate and homatropine methylbromide (Solution)

LabelerStrengthFirst seenLast seen
Actavis Pharma, Inc.HYDROCODONE BITARTRATE 5 mg/5mL; HOMATROPINE METHYLBROMIDE 1.5 mg/5mLAug 26, 2026Sep 2, 2026
Genus Lifesciences Inc.HYDROCODONE BITARTRATE 5 mg/5mL; HOMATROPINE METHYLBROMIDE 1.5 mg/5mLAug 26, 2026Sep 2, 2026
PAI Holdings, LLC dba PAI PharmaHYDROCODONE BITARTRATE 5 mg/5mL; HOMATROPINE METHYLBROMIDE 1.5 mg/5mLAug 26, 2026Sep 2, 2026
Actavis Pharma, Inc.HYDROCODONE BITARTRATE 1.5 mg/5mL; HOMATROPINE METHYLBROMIDE 5 mg/5mLJul 22, 2026Aug 19, 2026
Genus Lifesciences Inc.HYDROCODONE BITARTRATE 1.5 mg/5mL; HOMATROPINE METHYLBROMIDE 5 mg/5mLJul 22, 2026Aug 19, 2026
PAI Holdings, LLC dba PAI PharmaHYDROCODONE BITARTRATE 1.5 mg/5mL; HOMATROPINE METHYLBROMIDE 5 mg/5mLJul 22, 2026Aug 19, 2026
Actavis Pharma, Inc.HOMATROPINE METHYLBROMIDE 1.5 mg/5mL; HYDROCODONE BITARTRATE 5 mg/5mLJul 15, 2026Jul 15, 2026
Genus Lifesciences Inc.HOMATROPINE METHYLBROMIDE 1.5 mg/5mL; HYDROCODONE BITARTRATE 5 mg/5mLJul 15, 2026Jul 15, 2026
PAI Holdings, LLC dba PAI PharmaHOMATROPINE METHYLBROMIDE 1.5 mg/5mL; HYDROCODONE BITARTRATE 5 mg/5mLJul 15, 2026Jul 15, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Hydromet — NDC 00472-1030-16," retrieved September 3, 2026, https://drugdashboards.com/drug/00472103016.

Free to cite with attribution — see how the data is put together.