DrugDashboards

Spironolactone

spironolactone · SPIRONOLACTONE 25 mg/5mL · Suspension · Oral · Padagis US LLC

NDC 00574-1133-04 · 118 mL in 1 BOTTLE · NDA AUTHORIZED GENERIC · View full market →

The short version

5 companies supply this market — a reasonable cushion if one runs into trouble. The price is down 27% over the past year, to $1.57 per mL. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$1.57per MLinvoice-surveyed acquisition cost · Aug 19, 2026
  • Part D plans paid (avg)$0.1326per dosage unitgross, before rebates — matched by drug name · 2024
  • Part D point of sale (median)$2.09per unitnegotiated price across 65 plans — before rebates · Oct 1, 2024
  • Federal contracts pay (FSS)$64.45per package of 118MLPadagis Sourcing Solutions LLC · Jan 1, 2026

Medicare Part D

All Part D pricing →
ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$2.09per unit
middle half $2.06$2.10 · 65 plans · Oct 1, 2024
Est. net of rebates
≈ $2.09
generic — rebates are minimal, so net ≈ gross
Coverage & restrictions
of plans cover it

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 4 quarters since 2024.

NADAC price per unit

$0$1.00$2.00$3.00Apr 2024Sep 2026$1.57
30 price points · per MLSource: CMS NADAC

Estimated fill cost

WAC per package, as filed
$373.95
Reported to Texas DSHS · 2025 annual filing · Padagis US LLC

Manufacturer list price as filed — not what pharmacies actually pay after discounts.

Medicaid spend (2025)

$1.4M
5,518 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

13Low risk

Some pressure is visible, but not much — here’s everything the score found to count.

  • 5 active manufacturers+5
  • price down 27% year over year+8

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for spironolactone (other) in the next 90 days

sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Regulatory

Application
NDA209478
TE code
AB
Approval date
Aug 4, 2017
Patents / exclusivity
8 patents, 0 exclusivities
TypeNumber / codeExpires
patent9757394Oct 28, 2036
patent11395828Oct 28, 2036
patent10888570Oct 28, 2036
patent11389461Oct 28, 2036
patent10660907Oct 28, 2036
patent10624906Oct 28, 2036
patent10493083Oct 28, 2036
patent11491166Oct 28, 2036

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of spironolactone (Suspension)

LabelerStrengthFirst seenLast seen
Atlantic Biologicals Corp.SPIRONOLACTONE 25 mg/5mLSep 3, 2026Sep 3, 2026
Amneal Pharmaceuticals NY LLCSPIRONOLACTONE 25 mg/5mLJul 15, 2026Sep 2, 2026
Atlantic Biologicals Corp.SPIRONOLACTONE 25 mg/5mLJul 15, 2026Sep 2, 2026
Camber Pharmaceuticals, Inc.SPIRONOLACTONE 25 mg/5mLJul 15, 2026Sep 2, 2026
Padagis US LLCSPIRONOLACTONE 25 mg/5mLJul 15, 2026Sep 2, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Spironolactone — NDC 00574-1133-04," retrieved September 3, 2026, https://drugdashboards.com/drug/00574113304.

Free to cite with attribution — see how the data is put together.