DrugDashboards

Meperidine Hydrochloride

Meperidine Hydrochloride · MEPERIDINE HYDROCHLORIDE 50 mg/mL · Injection · Intramuscular; Intravenous; Subcutaneous · Hikma Pharmaceuticals USA Inc.

NDC 00641-6053-25 · 25 VIAL in 1 CARTON / 1 mL in 1 VIAL · ANDA · View full market →

The short version

Only one company currently supplies this market — there is no backup if it stumbles. It is in shortage right now.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Medicare Part B pays (ASP+6%)$6.34per billing unit (100 MG)HCPCS J2175 · Jul 1, 2026
  • Part D point of sale (median)$2.12per unitnegotiated price across 106 plans — before rebates · Apr 1, 2026

Medicare Part D

All Part D pricing →
ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$2.12per unit
middle half $2.10$8.23 · 106 plans · Apr 1, 2026
Est. net of rebates
≈ $2.12
generic — rebates are minimal, so net ≈ gross
Coverage & restrictions
2%of plans cover it
tier 2 · prior auth 81% · step therapy 0% · qty limit 19%

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.

NADAC price per unit

No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.

Estimated fill cost

WAC per package, as filed
$66.05
Reported to Texas DSHS · 2026 annual filing · Hikma Pharmaceuticals USA Inc.

Manufacturer list price as filed — not what pharmacies actually pay after discounts.

Medicare Part B (ASP)

Payment limit per 100 MG
$6.339
HCPCS J2175 · Jul 1, 2026 quarter · typically ASP + 6%

Medicaid spend (2025)

$6,989
1,154 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

Not scored — fragility is computed for NADAC-priced NDCs.

Where it's made

Establishments this product's FDA label declares, located via FDA registration data. How we built this →

Is this a "specialty" drug?

There's no legal definition — it meets 2 of 6 public criteria. Why that matters →

  • Part D specialty tier · median tier 2 across plans
  • Costs ≥ $950/fill
  • Biologic (BLA)
  • Injectable / infused
  • Orphan-drug exclusivity
  • REMS program · Opioid Analgesic REMS Shared System REMS

Regulatory

Application
ANDA080445
TE code
AP
Approval date
Jan 1, 1982
Patents / exclusivity
None on file

Shortage history

  • In shortage now Meperidine Hydrochloride, Injection, 100 mg/1 mL (NDC 0641-6054-25)May 30, 2025
    month 16 of a typical 20 for injectable shortages · model puts 26% odds it resolves within 6 months
  • In shortage now Meperidine Hydrochloride, Injection, 25 mg/1 mL (NDC 0641-6052-25)May 30, 2025
    month 16 of a typical 20 for injectable shortages · model puts 26% odds it resolves within 6 months
  • In shortage now Meperidine Hydrochloride, Injection, 50 mg/1 mL (NDC 0641-6053-25)May 30, 2025
    month 16 of a typical 20 for injectable shortages · model puts 26% odds it resolves within 6 months

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of Meperidine Hydrochloride (Injection)

LabelerStrengthFirst seenLast seen
Hikma Pharmaceuticals USA Inc.MEPERIDINE HYDROCHLORIDE 100 mg/mLJul 15, 2026Sep 2, 2026
Hikma Pharmaceuticals USA Inc.MEPERIDINE HYDROCHLORIDE 25 mg/mLJul 15, 2026Sep 2, 2026
Hikma Pharmaceuticals USA Inc.MEPERIDINE HYDROCHLORIDE 50 mg/mLJul 15, 2026Sep 2, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Meperidine Hydrochloride — NDC 00641-6053-25," retrieved September 3, 2026, https://drugdashboards.com/drug/00641605325.

Free to cite with attribution — see how the data is put together.