Carbidopa, Levodopa, and Entacapone · CARBIDOPA 25 mg/1; LEVODOPA 100 mg/1; ENTACAPONE 200 mg/1 · Tablet, Film Coated · Oral · Sandoz Inc
NDC 00781-5637-01 · 100 TABLET, FILM COATED in 1 BOTTLE · NDA AUTHORIZED GENERIC · View full market →
Only one company currently supplies this market — there is no backup if it stumbles. The price has held steady around $0.6826 per unit over the past year. Put together: worth watching — several of the pressures that precede supply trouble are present at once.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.
Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.
Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.
Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.
Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.
*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 5 quarters since 2024.
Estimates: latest NADAC unit price × quantity. Pharmacy acquisition cost only — excludes dispensing fees, markup, and insurance terms.
The score is counting real pressure here. One of these alone is routine; it’s the combination that makes this market worth watching.
The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026
sole-source market · 1 Class I/II recall(s) in 12 months
For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.
Backtested statistical model over the whole market, not this package alone. Model details →
No FDA shortage reports for this drug or its presentations.
No enforcement reports list this package NDC.
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| Sandoz Inc | CARBIDOPA 37.5 mg/1; LEVODOPA 150 mg/1; ENTACAPONE 200 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Sandoz Inc | CARBIDOPA 18.75 mg/1; LEVODOPA 75 mg/1; ENTACAPONE 200 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Sandoz Inc | CARBIDOPA 50 mg/1; LEVODOPA 200 mg/1; ENTACAPONE 200 mg/1 | Jul 22, 2026 | Sep 2, 2026 |
| Sandoz Inc | CARBIDOPA 12.5 mg/1; LEVODOPA 50 mg/1; ENTACAPONE 200 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Sandoz Inc | CARBIDOPA 25 mg/1; LEVODOPA 100 mg/1; ENTACAPONE 200 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Sandoz Inc | CARBIDOPA 31.25 mg/1; LEVODOPA 125 mg/1; ENTACAPONE 200 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Sandoz Inc | CARBIDOPA 12.5 mg/1; LEVODOPA 200 mg/1; ENTACAPONE 50 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Sandoz Inc | CARBIDOPA 31.25 mg/1; LEVODOPA 200 mg/1; ENTACAPONE 125 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Sandoz Inc | CARBIDOPA 37.5 mg/1; LEVODOPA 200 mg/1; ENTACAPONE 150 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Sandoz Inc | CARBIDOPA 18.75 mg/1; LEVODOPA 200 mg/1; ENTACAPONE 75 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Sandoz Inc | CARBIDOPA 25 mg/1; LEVODOPA 200 mg/1; ENTACAPONE 100 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Orion Corporation, Orion Pharma | CARBIDOPA 50 mg/1; LEVODOPA 200 mg/1; ENTACAPONE 200 mg/1 | Jul 22, 2026 | Jul 29, 2026 |
| Orion Corporation, Orion Pharma | CARBIDOPA 50 mg/1; ENTACAPONE 200 mg/1; LEVODOPA 200 mg/1 | Jul 15, 2026 | Jul 15, 2026 |
| Sandoz Inc | CARBIDOPA 31.25 mg/1; ENTACAPONE 200 mg/1; LEVODOPA 125 mg/1 | Jul 15, 2026 | Jul 15, 2026 |
| Sandoz Inc | CARBIDOPA 18.75 mg/1; ENTACAPONE 200 mg/1; LEVODOPA 75 mg/1 | Jul 15, 2026 | Jul 15, 2026 |
| Sandoz Inc | CARBIDOPA 25 mg/1; ENTACAPONE 200 mg/1; LEVODOPA 100 mg/1 | Jul 15, 2026 | Jul 15, 2026 |
| Sandoz Inc | CARBIDOPA 12.5 mg/1; ENTACAPONE 200 mg/1; LEVODOPA 50 mg/1 | Jul 15, 2026 | Jul 15, 2026 |
| Sandoz Inc | CARBIDOPA 37.5 mg/1; ENTACAPONE 200 mg/1; LEVODOPA 150 mg/1 | Jul 15, 2026 | Jul 15, 2026 |
| Sandoz Inc | CARBIDOPA 50 mg/1; ENTACAPONE 200 mg/1; LEVODOPA 200 mg/1 | Jul 15, 2026 | Jul 15, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
DrugDashboards, "Carbidopa, Levodopa, and Entacapone — NDC 00781-5637-01," retrieved September 3, 2026, https://drugdashboards.com/drug/00781563701.
Free to cite with attribution — see how the data is put together.