Sitagliptin and Metformin Hydrochloride · SITAGLIPTIN PHOSPHATE 50 mg/1; METFORMIN HYDROCHLORIDE 1000 mg/1 · Tablet, Film Coated · Oral · Sandoz Inc
NDC 00781-5802-60 · 60 TABLET, FILM COATED in 1 BOTTLE · ANDA · View full market →
9 companies supply this market — a reasonable cushion if one runs into trouble. The brand (Janumet) runs $5.28 per unit — 2.9× more. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
Matched to CMS's representative package for this drug (NDC 00006-0577-61) — same generic, strength, and dosage form. CMS prices one NDC per drug concept, not every package.
Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.
Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.
*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.
Estimates: latest NADAC unit price × quantity. Pharmacy acquisition cost only — excludes dispensing fees, markup, and insurance terms.
Nothing here is signaling trouble: several manufacturers, no current shortage, no recent serious recalls, stable pricing. In drug supply, boring is the good outcome.
The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026
sole-source market
For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.
Backtested statistical model over the whole market, not this package alone. Model details →
| Type | Number / code | Expires |
|---|---|---|
| exclusivity | PC | Nov 24, 2026 |
| exclusivity | PC | Nov 24, 2026 |
No FDA shortage reports for this drug or its presentations.
No enforcement reports list this package NDC.
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| MSD International GmbH (Singapore Branch) | SITAGLIPTIN PHOSPHATE 50 mg/1; METFORMIN HYDROCHLORIDE 500 mg/1 | Aug 20, 2026 | Sep 3, 2026 |
| Patheon Puerto Rico, Inc. | SITAGLIPTIN PHOSPHATE 50 mg/1; METFORMIN HYDROCHLORIDE 500 mg/1 | Aug 20, 2026 | Sep 3, 2026 |
| Patheon Puerto Rico, Inc. | SITAGLIPTIN PHOSPHATE 50 mg/1; METFORMIN HYDROCHLORIDE 1000 mg/1 | Aug 20, 2026 | Sep 3, 2026 |
| Zydus Lifesciences Limited | SITAGLIPTIN 50 mg/1; METFORMIN HYDROCHLORIDE 1000 mg/1 | Aug 26, 2026 | Sep 3, 2026 |
| A-S Medication Solutions | SITAGLIPTIN PHOSPHATE 50 mg/1; METFORMIN HYDROCHLORIDE 500 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| A-S Medication Solutions | SITAGLIPTIN PHOSPHATE 50 mg/1; METFORMIN HYDROCHLORIDE 1000 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Apotex Corp. | SITAGLIPTIN PHOSPHATE 50 mg/1; METFORMIN HYDROCHLORIDE 500 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Apotex Corp. | SITAGLIPTIN PHOSPHATE 50 mg/1; METFORMIN HYDROCHLORIDE 1000 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Golden State Medical Supply, Inc. | SITAGLIPTIN PHOSPHATE 50 mg/1; METFORMIN HYDROCHLORIDE 1000 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Golden State Medical Supply, Inc. | SITAGLIPTIN PHOSPHATE 50 mg/1; METFORMIN HYDROCHLORIDE 500 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Merck Sharp & Dohme LLC | SITAGLIPTIN PHOSPHATE 50 mg/1; METFORMIN HYDROCHLORIDE 500 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Merck Sharp & Dohme LLC | SITAGLIPTIN PHOSPHATE 50 mg/1; METFORMIN HYDROCHLORIDE 1000 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Sandoz Inc | SITAGLIPTIN PHOSPHATE 50 mg/1; METFORMIN HYDROCHLORIDE 1000 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Sandoz Inc | SITAGLIPTIN PHOSPHATE 50 mg/1; METFORMIN HYDROCHLORIDE 500 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Zydus Pharmaceuticals (USA) Inc. | SITAGLIPTIN 50 mg/1; METFORMIN HYDROCHLORIDE 1000 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Patheon Puerto Rico, Inc. | SITAGLIPTIN PHOSPHATE 50 mg/1; METFORMIN HYDROCHLORIDE 850 mg/1 | Aug 20, 2026 | Aug 31, 2026 |
| Zydus Lifesciences Limited | SITAGLIPTIN 50 mg/1; METFORMIN HYDROCHLORIDE 500 mg/1 | Aug 26, 2026 | Aug 31, 2026 |
| Zydus Pharmaceuticals (USA) Inc. | SITAGLIPTIN 50 mg/1; METFORMIN HYDROCHLORIDE 500 mg/1 | Aug 26, 2026 | Aug 28, 2026 |
| Golden State Medical Supply, Inc. | SITAGLIPTIN PHOSPHATE 1000 mg/1; METFORMIN HYDROCHLORIDE 50 mg/1 | Aug 15, 2026 | Aug 22, 2026 |
| Golden State Medical Supply, Inc. | SITAGLIPTIN PHOSPHATE 500 mg/1; METFORMIN HYDROCHLORIDE 50 mg/1 | Aug 15, 2026 | Aug 22, 2026 |
| Zydus Pharmaceuticals (USA) Inc. | SITAGLIPTIN 1000 mg/1; METFORMIN HYDROCHLORIDE 50 mg/1 | Jul 22, 2026 | Aug 22, 2026 |
| Zydus Lifesciences Limited | SITAGLIPTIN 1000 mg/1; METFORMIN HYDROCHLORIDE 50 mg/1 | Jul 22, 2026 | Aug 21, 2026 |
| Zydus Lifesciences Limited | SITAGLIPTIN 500 mg/1; METFORMIN HYDROCHLORIDE 50 mg/1 | Jul 22, 2026 | Aug 21, 2026 |
| Zydus Pharmaceuticals (USA) Inc. | SITAGLIPTIN 500 mg/1; METFORMIN HYDROCHLORIDE 50 mg/1 | Jul 22, 2026 | Aug 21, 2026 |
| A-S Medication Solutions | SITAGLIPTIN PHOSPHATE 500 mg/1; METFORMIN HYDROCHLORIDE 50 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| A-S Medication Solutions | SITAGLIPTIN PHOSPHATE 1000 mg/1; METFORMIN HYDROCHLORIDE 50 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Apotex Corp. | SITAGLIPTIN PHOSPHATE 500 mg/1; METFORMIN HYDROCHLORIDE 50 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Apotex Corp. | SITAGLIPTIN PHOSPHATE 1000 mg/1; METFORMIN HYDROCHLORIDE 50 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Merck Sharp & Dohme LLC | SITAGLIPTIN PHOSPHATE 1000 mg/1; METFORMIN HYDROCHLORIDE 50 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Merck Sharp & Dohme LLC | SITAGLIPTIN PHOSPHATE 500 mg/1; METFORMIN HYDROCHLORIDE 50 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| MSD International GmbH (Singapore Branch) | SITAGLIPTIN PHOSPHATE 500 mg/1; METFORMIN HYDROCHLORIDE 50 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Patheon Puerto Rico, Inc. | SITAGLIPTIN PHOSPHATE 1000 mg/1; METFORMIN HYDROCHLORIDE 50 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Patheon Puerto Rico, Inc. | SITAGLIPTIN PHOSPHATE 500 mg/1; METFORMIN HYDROCHLORIDE 50 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Sandoz Inc | SITAGLIPTIN PHOSPHATE 500 mg/1; METFORMIN HYDROCHLORIDE 50 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Sandoz Inc | SITAGLIPTIN PHOSPHATE 1000 mg/1; METFORMIN HYDROCHLORIDE 50 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Patheon Puerto Rico, Inc. | SITAGLIPTIN PHOSPHATE 850 mg/1; METFORMIN HYDROCHLORIDE 50 mg/1 | Jul 22, 2026 | Aug 16, 2026 |
| Zydus Lifesciences Limited | METFORMIN HYDROCHLORIDE 1000 mg/1; SITAGLIPTIN 50 mg/1 | Jul 15, 2026 | Jul 19, 2026 |
| Zydus Lifesciences Limited | METFORMIN HYDROCHLORIDE 500 mg/1; SITAGLIPTIN 50 mg/1 | Jul 15, 2026 | Jul 19, 2026 |
| Zydus Pharmaceuticals (USA) Inc. | METFORMIN HYDROCHLORIDE 1000 mg/1; SITAGLIPTIN 50 mg/1 | Jul 15, 2026 | Jul 18, 2026 |
| Patheon Puerto Rico, Inc. | METFORMIN HYDROCHLORIDE 850 mg/1; SITAGLIPTIN PHOSPHATE 50 mg/1 | Jul 15, 2026 | Jul 16, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
DrugDashboards, "Sitagliptin and Metformin Hydrochloride — NDC 00781-5802-60," retrieved September 3, 2026, https://drugdashboards.com/drug/00781580260.
Free to cite with attribution — see how the data is put together.