DrugDashboards

Ursodiol

Ursodiol · URSODIOL 300 mg/1 · Capsule · Oral · Major Pharmaceuticals

NDC 00904-6221-06 · 50 BLISTER PACK in 1 CARTON / 1 CAPSULE in 1 BLISTER PACK · ANDA · View full market →

The short version

22 companies supply this market — deep enough that no single failure threatens the supply. The price is down 18% over the past year, to $0.4160 per unit. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$0.4160per EAinvoice-surveyed acquisition cost · Aug 19, 2026
  • Part D plans paid (avg)$1.20per dosage unitgross, before rebates — matched by drug name · 2024
  • Medicaid generic ceiling (FUL)$0.4160per CAPweighted avg manufacturer price $0.1941 · Aug 1, 2026100% of what pharmacies pay — higher than 10% of drugs with this benchmark

Medicare Part D

All Part D pricing →

Matched to CMS's representative package for this drug (NDC 00527-1326-01) — same generic, strength, and dosage form. CMS prices one NDC per drug concept, not every package.

ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$0.8092per unit
middle half $0.6735$1.31 · 5,452 plans · Apr 1, 2026
Est. net of rebates
≈ $0.8092
generic — rebates are minimal, so net ≈ gross
Coverage & restrictions
99%of plans cover it
tier 3 · prior auth 0% · step therapy 0% · qty limit 0%

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 2 quarters since 2024.

NADAC price per unit

$0$1.00$2.00$3.00Oct 2017Sep 2026$0.416
86 price points · per EA · dashed = manufacturer avg (WAMP)Source: CMS NADAC

Estimated fill cost

#30 count
$12.48
#90 count
$37.44

Estimates: latest NADAC unit price × quantity. Pharmacy acquisition cost only — excludes dispensing fees, markup, and insurance terms.

Supply fragility

0Low risk

Nothing here is signaling trouble: several manufacturers, no current shortage, no recent serious recalls, stable pricing. In drug supply, boring is the good outcome.

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for ursodiol (oral solid) in the next 90 days

sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Regulatory

Application
ANDA075517
TE code
AB
Approval date
Mar 14, 2000
Patents / exclusivity
None on file

Shortage history

  • Planned discontinuation Ursodiol, Capsule, 300 mg (NDC 64380-844-06)Apr 6, 2026

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of Ursodiol (Capsule)

LabelerStrengthFirst seenLast seen
AvPAKURSODIOL 300 mg/1Jul 15, 2026Sep 3, 2026
American Health PackagingURSODIOL 300 mg/1Jul 15, 2026Sep 2, 2026
Amneal Pharmaceuticals NY LLCURSODIOL 300 mg/1Jul 15, 2026Sep 2, 2026
AvKAREURSODIOL 300 mg/1Jul 15, 2026Sep 2, 2026
Chartwell RX, LLCURSODIOL 300 mg/1Jul 15, 2026Sep 2, 2026
Epic Pharma, LLCURSODIOL 300 mg/1Jul 15, 2026Sep 2, 2026
FH2 Pharma LLCURSODIOL 400 mg/1Jul 15, 2026Sep 2, 2026
FH2 Pharma LLCURSODIOL 200 mg/1Jul 15, 2026Sep 2, 2026
Golden State Medical Supply, Inc.URSODIOL 300 mg/1Jul 15, 2026Sep 2, 2026
Intra-Sana LaboratoriesURSODIOL 400 mg/1Jul 15, 2026Sep 2, 2026
Intra-Sana LaboratoriesURSODIOL 200 mg/1Jul 15, 2026Sep 2, 2026
Lannett Company, Inc.URSODIOL 300 mg/1Jul 15, 2026Sep 2, 2026
Laurus Labs LimitedURSODIOL 300 mg/1Jul 15, 2026Sep 2, 2026
Major PharmaceuticalsURSODIOL 300 mg/1Jul 15, 2026Sep 2, 2026
NorthStar Rx LLCURSODIOL 300 mg/1Jul 15, 2026Sep 2, 2026
Pangea Pharmaceuticals, LLCURSODIOL 150 mg/1Jul 15, 2026Sep 2, 2026
Strides Pharma Science LimitedURSODIOL 300 mg/1Jul 15, 2026Sep 2, 2026
VGYAAN Pharmaceuticals LLCURSODIOL 300 mg/1Jul 15, 2026Sep 2, 2026
Zydus Lifesciences LimitedURSODIOL 300 mg/1Jul 15, 2026Sep 2, 2026
Zydus Pharmaceuticals (USA) Inc.URSODIOL 300 mg/1Jul 15, 2026Sep 2, 2026
Actavis Pharma, Inc.URSODIOL 300 mg/1Jul 15, 2026Aug 31, 2026
Aurobindo Pharma LimitedURSODIOL 300 mg/1Jul 15, 2026Aug 31, 2026
Bryant Ranch PrepackURSODIOL 300 mg/1Jul 15, 2026Aug 31, 2026
PuraCap Laboratories, LLCURSODIOL 300 mg/1Jul 15, 2026Aug 31, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Ursodiol — NDC 00904-6221-06," retrieved September 3, 2026, https://drugdashboards.com/drug/00904622106.

Free to cite with attribution — see how the data is put together.