Acetaminophen, Diphenhydramine Hydrochloride · DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1; ACETAMINOPHEN 500 mg/1 · Tablet, Film Coated · Oral · Major Pharmaceuticals
NDC 00904-6731-51 · 1 BOTTLE in 1 CARTON / 50 TABLET, FILM COATED in 1 BOTTLE · OTC MONOGRAPH DRUG · View full market →
7 companies supply this market — a reasonable cushion if one runs into trouble. The price has held steady around $0.0444 per unit over the past year. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.
Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.
Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.
Medicare Part D does not cover over-the-counter drugs — by law it pays only for products requiring a prescription.
How Part D pricing works →Estimates: latest NADAC unit price × quantity. Pharmacy acquisition cost only — excludes dispensing fees, markup, and insurance terms.
Nothing here is signaling trouble: several manufacturers, no current shortage, no recent serious recalls, stable pricing. In drug supply, boring is the good outcome.
The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026
sole-source market
For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.
Backtested statistical model over the whole market, not this package alone. Model details →
There's no legal definition — it meets 1 of 6 public criteria. Why that matters →
No FDA shortage reports for this drug or its presentations.
No enforcement reports list this package NDC.
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| Contract Pharmacal Corp. | DIPHENHYDRAMINE HYDROCHLORIDE 50 mg/1; ACETAMINOPHEN 325 mg/1 | Aug 20, 2026 | Sep 3, 2026 |
| JC World Bell Wholesale Co., Inc. | ACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Jones Healthcare Group - Packaging Services, Inc | ACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| LEADER/ Cardinal Health 110, Inc. | ACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Major Pharmaceuticals | DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1; ACETAMINOPHEN 500 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Savings Distributors LLC | ACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Strive Pharmaceuticals Inc. | ACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Contract Pharmacal Corp. | DIPHENHYDRAMINE HYDROCHLORIDE 325 mg/1; ACETAMINOPHEN 50 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Major Pharmaceuticals | DIPHENHYDRAMINE HYDROCHLORIDE 500 mg/1; ACETAMINOPHEN 25 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Contract Pharmacal Corp. | ACETAMINOPHEN 325 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 50 mg/1 | Jul 15, 2026 | Jul 15, 2026 |
| Major Pharmaceuticals | ACETAMINOPHEN 500 mg/1; DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1 | Jul 15, 2026 | Jul 15, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
DrugDashboards, "Acetaminophen PM — NDC 00904-6731-51," retrieved September 3, 2026, https://drugdashboards.com/drug/00904673151.
Free to cite with attribution — see how the data is put together.