DrugDashboards

Aminosyn II

ISOLEUCINE, LEUCINE, LYSINE ACETATE, METHIONINE, PHENYLALANINE, THREONINE, TRYPTOPHAN, VALINE, ALANINE, ARGININE, ASPARTIC ACID, GLUTAMIC ACID, HISTIDINE, PROLINE, SERINE, N-ACETYLTYROSINE, and GLYCINE · ISOLEUCINE 660 mg/100mL; LEUCINE 1000 mg/100mL; LYSINE ACETATE 1050 mg/100mL; METHIONINE 172 mg/100mL; PHENYLALANINE 298 mg/100mL; THREONINE 400 mg/100mL; TRYPTOPHAN 200 mg/100mL; VALINE 500 mg/100mL; ALANINE 993 mg/100mL; ARGININE 1018 mg/100mL; ASPARTIC ACID 700 mg/100mL; GLUTAMIC ACID 738 mg/100mL; HISTIDINE 300 mg/100mL; PROLINE 722 mg/100mL; SERINE 530 mg/100mL; ACETYL L-TYROSINE 270 mg/100mL; GLYCINE 500 mg/100mL · Injection, Solution · Intravenous · ICU Medical Inc.

NDC 00990-7172-17 · 6 POUCH in 1 CASE / 1 BAG in 1 POUCH / 2000 mL in 1 BAG · NDA · View full market →

The short version

Only one company currently supplies this market — there is no backup if it stumbles. It is in shortage right now.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

Medicare Part D

No Medicare Part D plan in CMS's quarterly files lists this product. That usually means it is discontinued, a repackager's listing, or a product no plan has added to its formulary.

How Part D pricing works →

NADAC price per unit

No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.

Estimated fill cost

WAC per package, as filed
$47.06
Reported to Texas DSHS · 2026 annual filing · Otsuka ICU Medical LLC

Manufacturer list price as filed — not what pharmacies actually pay after discounts.

Supply fragility

Not scored — fragility is computed for NADAC-priced NDCs.

Is this a "specialty" drug?

There's no legal definition — it meets 1 of 6 public criteria. Why that matters →

  • Part D specialty tier
  • Costs ≥ $950/fill
  • Biologic (BLA)
  • Injectable / infused
  • Orphan-drug exclusivity
  • REMS program

Regulatory

Application
NDA020015
TE code
—
Approval date
Dec 19, 1991
Patents / exclusivity
None on file

Shortage history

  • In shortage now — Aminosyn II 10% In Plastic Container, Injection, 0.1 (NDC 0990-7172-17)Dec 8, 2020
    month 69 — 3× the typical 20-month injectable shortage
  • In shortage now — Aminosyn II 15% In Plastic Container, Injection, 0.15 (NDC 0990-7171-17)Dec 8, 2020
    month 69 — 3× the typical 20-month injectable shortage

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of ISOLEUCINE, LEUCINE, LYSINE ACETATE, METHIONINE, PHENYLALANINE, THREONINE, TRYPTOPHAN, VALINE, ALANINE, ARGININE, ASPARTIC ACID, GLUTAMIC ACID, HISTIDINE, PROLINE, SERINE, N-ACETYLTYROSINE, and GLYCINE (Injection, Solution)

LabelerStrengthFirst seenLast seen
ICU Medical Inc.ISOLEUCINE 660 mg/100mL; LEUCINE 1000 mg/100mL; LYSINE ACETATE 1050 mg/100mL; METHIONINE 172 mg/100mL; PHENYLALANINE 298 mg/100mL; THREONINE 400 mg/100mL; TRYPTOPHAN 200 mg/100mL; VALINE 500 mg/100mL; ALANINE 993 mg/100mL; ARGININE 1018 mg/100mL; ASPARTIC ACID 700 mg/100mL; GLUTAMIC ACID 738 mg/100mL; HISTIDINE 300 mg/100mL; PROLINE 722 mg/100mL; SERINE 530 mg/100mL; ACETYL L-TYROSINE 270 mg/100mL; GLYCINE 500 mg/100mLAug 26, 2026Sep 2, 2026
ICU Medical Inc.ISOLEUCINE 990 mg/100mL; LEUCINE 1500 mg/100mL; LYSINE ACETATE 1575 mg/100mL; METHIONINE 258 mg/100mL; PHENYLALANINE 447 mg/100mL; THREONINE 600 mg/100mL; TRYPTOPHAN 300 mg/100mL; VALINE 750 mg/100mL; ALANINE 1490 mg/100mL; ARGININE 1527 mg/100mL; ASPARTIC ACID 1050 mg/100mL; GLUTAMIC ACID 1107 mg/100mL; HISTIDINE 450 mg/100mL; PROLINE 1083 mg/100mL; SERINE 795 mg/100mL; ACETYL L-TYROSINE 405 mg/100mL; GLYCINE 750 mg/100mLAug 26, 2026Sep 2, 2026
ICU Medical Inc.ISOLEUCINE 270 mg/100mL; LEUCINE 993 mg/100mL; LYSINE ACETATE 1018 mg/100mL; METHIONINE 700 mg/100mL; PHENYLALANINE 738 mg/100mL; THREONINE 500 mg/100mL; TRYPTOPHAN 300 mg/100mL; VALINE 660 mg/100mL; ALANINE 1000 mg/100mL; ARGININE 1050 mg/100mL; ASPARTIC ACID 172 mg/100mL; GLUTAMIC ACID 298 mg/100mL; HISTIDINE 722 mg/100mL; PROLINE 530 mg/100mL; SERINE 400 mg/100mL; ACETYL L-TYROSINE 200 mg/100mL; GLYCINE 500 mg/100mLJul 22, 2026Aug 19, 2026
ICU Medical Inc.ISOLEUCINE 405 mg/100mL; LEUCINE 1490 mg/100mL; LYSINE ACETATE 1527 mg/100mL; METHIONINE 1050 mg/100mL; PHENYLALANINE 1107 mg/100mL; THREONINE 750 mg/100mL; TRYPTOPHAN 450 mg/100mL; VALINE 990 mg/100mL; ALANINE 1500 mg/100mL; ARGININE 1575 mg/100mL; ASPARTIC ACID 258 mg/100mL; GLUTAMIC ACID 447 mg/100mL; HISTIDINE 1083 mg/100mL; PROLINE 795 mg/100mL; SERINE 600 mg/100mL; ACETYL L-TYROSINE 300 mg/100mL; GLYCINE 750 mg/100mLJul 22, 2026Aug 19, 2026
ICU Medical Inc.ACETYL L-TYROSINE 270 mg/100mL; ALANINE 993 mg/100mL; ARGININE 1018 mg/100mL; ASPARTIC ACID 700 mg/100mL; GLUTAMIC ACID 738 mg/100mL; GLYCINE 500 mg/100mL; HISTIDINE 300 mg/100mL; ISOLEUCINE 660 mg/100mL; LEUCINE 1000 mg/100mL; LYSINE ACETATE 1050 mg/100mL; METHIONINE 172 mg/100mL; PHENYLALANINE 298 mg/100mL; PROLINE 722 mg/100mL; SERINE 530 mg/100mL; THREONINE 400 mg/100mL; TRYPTOPHAN 200 mg/100mL; VALINE 500 mg/100mLJul 15, 2026Jul 15, 2026
ICU Medical Inc.ACETYL L-TYROSINE 405 mg/100mL; ALANINE 1490 mg/100mL; ARGININE 1527 mg/100mL; ASPARTIC ACID 1050 mg/100mL; GLUTAMIC ACID 1107 mg/100mL; GLYCINE 750 mg/100mL; HISTIDINE 450 mg/100mL; ISOLEUCINE 990 mg/100mL; LEUCINE 1500 mg/100mL; LYSINE ACETATE 1575 mg/100mL; METHIONINE 258 mg/100mL; PHENYLALANINE 447 mg/100mL; PROLINE 1083 mg/100mL; SERINE 795 mg/100mL; THREONINE 600 mg/100mL; TRYPTOPHAN 300 mg/100mL; VALINE 750 mg/100mLJul 15, 2026Jul 15, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Aminosyn II — NDC 00990-7172-17," retrieved September 3, 2026, https://drugdashboards.com/drug/00990717217.

Free to cite with attribution — see how the data is put together.