DrugDashboards

acetaminophen, dextromethorphan hbr, doxylamine succinate capsule

acetaminophen, dextromethorphan hbr, doxylamine succinate capsule · DOXYLAMINE SUCCINATE 6.25 mg/1; DEXTROMETHORPHAN HYDROBROMIDE 10 mg/1; ACETAMINOPHEN 325 mg/1 · Capsule, Liquid Filled · Patheon Softgels Inc.

NDC 10888-8259-01 · 8000 CAPSULE, LIQUID FILLED in 1 BOX · DRUG FOR FURTHER PROCESSING · View full market →

Bulk ingredient — not a finished product

This NDC is a raw material (drug for further processing) sold to drug manufacturers or compounders, not a product pharmacies dispense. Retail pricing, TE codes, fragility scores, and shortage reports don't apply to bulk listings — those attach to finished products made from this ingredient.

Medicare Part D

This is a bulk ingredient, not a dispensable product — it is a raw material sold to manufacturers and compounders, so no plan prices it.

How Part D pricing works →

NADAC price per unit

No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.

Supply fragility

Not scored — fragility is computed for NADAC-priced NDCs.

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for acetaminophen, dextromethorphan hbr, doxylamine succinate (oral solid) in the next 90 days

sole-source market · price up 1% YoY

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Is this a "specialty" drug?

There's no legal definition — it meets 1 of 6 public criteria. Why that matters →

  • Part D specialty tier
  • Costs ≥ $950/fill
  • Biologic (BLA)
  • Injectable / infused
  • Orphan-drug exclusivity
  • REMS program · Opioid Analgesic REMS Shared System REMS

Regulatory

Application
TE code
Approval date
Patents / exclusivity

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of acetaminophen, dextromethorphan hbr, doxylamine succinate capsule (Capsule, Liquid Filled)

LabelerStrengthFirst seenLast seen
Patheon Softgels Inc.DOXYLAMINE SUCCINATE 6.25 mg/1; DEXTROMETHORPHAN HYDROBROMIDE 10 mg/1; ACETAMINOPHEN 325 mg/1Aug 20, 2026Sep 3, 2026
Patheon Softgels Inc.DOXYLAMINE SUCCINATE 325 mg/1; DEXTROMETHORPHAN HYDROBROMIDE 10 mg/1; ACETAMINOPHEN 6.25 mg/1Jul 22, 2026Aug 19, 2026
Patheon Softgels Inc.ACETAMINOPHEN 325 mg/1; DEXTROMETHORPHAN HYDROBROMIDE 10 mg/1; DOXYLAMINE SUCCINATE 6.25 mg/1Jul 15, 2026Jul 15, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "acetaminophen, dextromethorphan hbr, doxylamine succinate capsule — NDC 10888-8259-01," retrieved September 3, 2026, https://drugdashboards.com/drug/10888825901.

Free to cite with attribution — see how the data is put together.