DrugDashboards

Butalbital, Acetaminophen, and Caffeine

Butalbital, Acetaminophen, and Caffeine · BUTALBITAL 300 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1 · Capsule · Oral · Northstar Rx Llc

NDC 16714-0170-01 · 100 CAPSULE in 1 BOTTLE · ANDA · View full market →

The short version

Just 3 companies supply this market — thin enough that a single exit would be felt immediately. The price is down 23% over the past year, to $0.3355 per unit. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$0.3355per EAinvoice-surveyed acquisition cost · Jun 17, 2026
  • Medicaid generic ceiling (FUL)$0.5046per CAPweighted avg manufacturer price $0.2756 · Aug 1, 2024150% of what pharmacies pay — higher than 81% of drugs with this benchmark

Medicare Part D

No Medicare Part D plan in CMS's quarterly files lists this product. That usually means it is discontinued, a repackager's listing, or a product no plan has added to its formulary.

How Part D pricing works →

NADAC price per unit

$0$0.5$1.00May 2021Sep 2026$0.3355
63 price points · per EA · held since Invalid Date · dashed = manufacturer avg (WAMP)Source: CMS NADAC

Estimated fill cost

#30 count
$10.07
#90 count
$30.20

Estimates: latest NADAC unit price × quantity. Pharmacy acquisition cost only — excludes dispensing fees, markup, and insurance terms.

Medicaid spend (2025)

$111,493
4,241 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

18Low risk

Some pressure is visible, but not much — here’s everything the score found to count.

  • 3 active manufacturers+10
  • price down 26% year over year+8

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for butalbital, acetaminophen and caffeine (oral solid) in the next 90 days

OAI inspection at a producing facility (24 months) · sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Is this a "specialty" drug?

There's no legal definition — it meets 1 of 6 public criteria. Why that matters →

  • Part D specialty tier
  • Costs ≥ $950/fill
  • Biologic (BLA)
  • Injectable / infused
  • Orphan-drug exclusivity
  • REMS program · Opioid Analgesic REMS Shared System REMS

Regulatory

Application
ANDA213046
TE code
AA
Approval date
Jul 1, 2020
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of Butalbital, Acetaminophen, and Caffeine (Capsule)

LabelerStrengthFirst seenLast seen
AvKAREBUTALBITAL 50 mg/1; ACETAMINOPHEN 300 mg/1; CAFFEINE 40 mg/1Aug 26, 2026Sep 2, 2026
Sun Pharmaceutical Industries, Inc.BUTALBITAL 50 mg/1; ACETAMINOPHEN 300 mg/1; CAFFEINE 40 mg/1Aug 26, 2026Sep 2, 2026
Actavis Pharma, Inc.BUTALBITAL 50 mg/1; ACETAMINOPHEN 300 mg/1; CAFFEINE 40 mg/1Aug 26, 2026Aug 31, 2026
Actavis Pharma, Inc.BUTALBITAL 300 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1Jul 22, 2026Aug 20, 2026
AvKAREBUTALBITAL 300 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1Jul 22, 2026Aug 19, 2026
Sun Pharmaceutical Industries, Inc.BUTALBITAL 300 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1Jul 22, 2026Aug 19, 2026
Northstar Rx LlcBUTALBITAL 300 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1Jul 22, 2026Jul 22, 2026
Actavis Pharma, Inc.ACETAMINOPHEN 300 mg/1; BUTALBITAL 50 mg/1; CAFFEINE 40 mg/1Jul 15, 2026Jul 19, 2026
Sun Pharmaceutical Industries, Inc.ACETAMINOPHEN 300 mg/1; BUTALBITAL 50 mg/1; CAFFEINE 40 mg/1Jul 16, 2026Jul 16, 2026
AvKAREACETAMINOPHEN 300 mg/1; BUTALBITAL 50 mg/1; CAFFEINE 40 mg/1Jul 15, 2026Jul 15, 2026
Northstar Rx LlcACETAMINOPHEN 300 mg/1; BUTALBITAL 50 mg/1; CAFFEINE 40 mg/1Jul 15, 2026Jul 15, 2026
Taro Pharmaceuticals U.S.A., Inc.ACETAMINOPHEN 300 mg/1; BUTALBITAL 50 mg/1; CAFFEINE 40 mg/1Jul 15, 2026Jul 15, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Butalbital, Acetaminophen, and Caffeine — NDC 16714-0170-01," retrieved September 3, 2026, https://drugdashboards.com/drug/16714017001.

Free to cite with attribution — see how the data is put together.