The short version
4 companies supply this market — a reasonable cushion if one runs into trouble.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
Signature Care Eye Drops Advanced Relief
DEXTRAN 70, POLYETHYLENE GLYCOL 400, POVIDONE, TETRAHYDROZOLINE HCl · DEXTRAN 70 100 mg/100mL; POLYETHYLENE GLYCOL 400 1000 mg/100mL; POVIDONE 1000 mg/100mL; TETRAHYDROZOLINE HYDROCHLORIDE 50 mg/100mL · Solution/ Drops · Ophthalmic · Better Living Brands LLC
NDC 21130-0704-01 · 1 BOTTLE, DROPPER in 1 BOX / 15 mL in 1 BOTTLE, DROPPER · OTC MONOGRAPH DRUG · View full market →
Medicare Part D
Medicare Part D does not cover over-the-counter drugs — by law it pays only for products requiring a prescription.
How Part D pricing works →NADAC price per unit
No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.
Supply fragility
Not scored — fragility is computed for NADAC-priced NDCs.
90-day shortage risk (model v2)
0.1%chance of a new FDA shortage posting for dextran 70, polyethylene glycol 400, povidone, tetrahydrozoline hcl (other) in the next 90 days
sole-source market · price up 6% YoY · 1 Class I/II recall(s) in 12 months
For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.
Backtested statistical model over the whole market, not this package alone. Model details →
Regulatory
- Application
- M018
- TE code
- —
- Approval date
- —
- Patents / exclusivity
- None on file
Shortage history
No FDA shortage reports for this drug or its presentations.
Recalls (this NDC)
No enforcement reports list this package NDC.
Manufacturers of DEXTRAN 70, POLYETHYLENE GLYCOL 400, POVIDONE, TETRAHYDROZOLINE HCl (Solution/ Drops)
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| Better Living Brands LLC | DEXTRAN 70 100 mg/100mL; POLYETHYLENE GLYCOL 400 1000 mg/100mL; POVIDONE 1000 mg/100mL; TETRAHYDROZOLINE HYDROCHLORIDE 50 mg/100mL | Jul 15, 2026 | Sep 2, 2026 |
| Cardinal Health | DEXTRAN 70 100 mg/100mL; POLYETHYLENE GLYCOL 400 1000 mg/100mL; POVIDONE 1000 mg/100mL; TETRAHYDROZOLINE HYDROCHLORIDE 50 mg/100mL | Jul 15, 2026 | Sep 2, 2026 |
| Chain Drug Marketing Association, Inc. | DEXTRAN 70 .1 g/100mL; TETRAHYDROZOLINE HYDROCHLORIDE .05 g/100mL; POVIDONE 1 g/100mL; POLYETHYLENE GLYCOL 400 1 g/100mL | Aug 26, 2026 | Sep 2, 2026 |
| WinCo Foods, LLC | DEXTRAN 70 100 mg/100mL; POLYETHYLENE GLYCOL 400 1000 mg/100mL; POVIDONE 1000 mg/100mL; TETRAHYDROZOLINE HYDROCHLORIDE 50 mg/100mL | Jul 15, 2026 | Sep 2, 2026 |
| Chain Drug Marketing Association, Inc. | DEXTRAN 70 .1 g/100mL; TETRAHYDROZOLINE HYDROCHLORIDE 1 g/100mL; POVIDONE 1 g/100mL; POLYETHYLENE GLYCOL 400 .05 g/100mL | Jul 22, 2026 | Aug 19, 2026 |
| Chain Drug Marketing Association, Inc. | DEXTRAN 70 .1 g/100mL; POLYETHYLENE GLYCOL 400 1 g/100mL; POVIDONE 1 g/100mL; TETRAHYDROZOLINE HYDROCHLORIDE .05 g/100mL | Jul 15, 2026 | Jul 15, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
Cite this page
DrugDashboards, "Signature Care Eye Drops Advanced Relief — NDC 21130-0704-01," retrieved September 3, 2026, https://drugdashboards.com/drug/21130070401.
Free to cite with attribution — see how the data is put together.