The short version
Only one company currently supplies this market — there is no backup if it stumbles.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
Signature Care Hemorrhoidal Cream (with applicator)
Phenylephrine Hydrochloride, Pramoxine Hydrochloride, Glycerin, Petrolatum · PHENYLEPHRINE HYDROCHLORIDE 2.5 mg/g; PRAMOXINE HYDROCHLORIDE 10 mg/g; GLYCERIN 144 mg/g; PETROLATUM 150 mg/g · Cream · Topical · Better Living Brands, Llc
NDC 21130-0981-02 · 1 TUBE, WITH APPLICATOR in 1 CARTON / 57 g in 1 TUBE, WITH APPLICATOR · OTC MONOGRAPH DRUG · View full market →
Medicare Part D
Medicare Part D does not cover over-the-counter drugs — by law it pays only for products requiring a prescription.
How Part D pricing works →NADAC price per unit
No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.
Supply fragility
Not scored — fragility is computed for NADAC-priced NDCs.
Regulatory
- Application
- M015
- TE code
- —
- Approval date
- —
- Patents / exclusivity
- None on file
Shortage history
No FDA shortage reports for this drug or its presentations.
Recalls (this NDC)
No enforcement reports list this package NDC.
Manufacturers of Phenylephrine Hydrochloride, Pramoxine Hydrochloride, Glycerin, Petrolatum (Cream)
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| Better Living Brands, Llc | PHENYLEPHRINE HYDROCHLORIDE 2.5 mg/g; PRAMOXINE HYDROCHLORIDE 10 mg/g; GLYCERIN 144 mg/g; PETROLATUM 150 mg/g | Aug 26, 2026 | Sep 2, 2026 |
| Better Living Brands, Llc | PHENYLEPHRINE HYDROCHLORIDE 144 mg/g; PRAMOXINE HYDROCHLORIDE 150 mg/g; GLYCERIN 2.5 mg/g; PETROLATUM 10 mg/g | Jul 22, 2026 | Aug 19, 2026 |
| Better Living Brands, Llc | GLYCERIN 144 mg/g; PETROLATUM 150 mg/g; PHENYLEPHRINE HYDROCHLORIDE 2.5 mg/g; PRAMOXINE HYDROCHLORIDE 10 mg/g | Jul 15, 2026 | Jul 15, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
Cite this page
DrugDashboards, "Signature Care Hemorrhoidal Cream (with applicator) — NDC 21130-0981-02," retrieved September 3, 2026, https://drugdashboards.com/drug/21130098102.
Free to cite with attribution — see how the data is put together.