DrugDashboards

glyburide-metformin hydrochloride

glyburide-metformin hydrochloride · GLYBURIDE 1.25 mg/1; METFORMIN HYDROCHLORIDE 250 mg/1 · Tablet · Oral · Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.

NDC 23155-0233-01 · 100 TABLET in 1 BOTTLE · ANDA · View full market →

The short version

5 companies supply this market — a reasonable cushion if one runs into trouble. The price is down 27% over the past year, to $0.0335 per unit. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$0.0335per EAinvoice-surveyed acquisition cost · May 21, 2025
  • Medicaid generic ceiling (FUL)$0.0461per TABweighted avg manufacturer price $0.0216 · Mar 1, 2018138% of what pharmacies pay — higher than 76% of drugs with this benchmark

Medicare Part D

No Medicare Part D plan in CMS's quarterly files lists this product. That usually means it is discontinued, a repackager's listing, or a product no plan has added to its formulary.

How Part D pricing works →

NADAC price per unit

$0$0.05$0.1Nov 2013May 2025$0.0335
44 price points · per EA · last surveyed Invalid Date · dashed = manufacturer avg (WAMP)Source: CMS NADAC

Estimated fill cost

#30 count
$1.01
#90 count
$3.02

Estimates: latest NADAC unit price × quantity. Pharmacy acquisition cost only — excludes dispensing fees, markup, and insurance terms.

Medicaid spend (2025)

$1,152
71 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

5Low risk

Some pressure is visible, but not much — here’s everything the score found to count.

  • 5 active manufacturers+5

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for glyburide and metformin hydrochloride (oral solid) in the next 90 days

sole-source market · price up 3% YoY

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Regulatory

Application
ANDA079009
TE code
AB
Approval date
Jun 3, 2009
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of glyburide-metformin hydrochloride (Tablet)

LabelerStrengthFirst seenLast seen
A-S Medication SolutionsGLYBURIDE 5 mg/1; METFORMIN HYDROCHLORIDE 500 mg/1Jul 15, 2026Sep 2, 2026
A-S Medication SolutionsGLYBURIDE 2.5 mg/1; METFORMIN HYDROCHLORIDE 500 mg/1Jul 15, 2026Sep 2, 2026
Bryant Ranch PrepackGLYBURIDE 5 mg/1; METFORMIN HYDROCHLORIDE 500 mg/1Jul 15, 2026Sep 2, 2026
Bryant Ranch PrepackGLYBURIDE 2.5 mg/1; METFORMIN HYDROCHLORIDE 500 mg/1Jul 15, 2026Sep 2, 2026
Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.GLYBURIDE 1.25 mg/1; METFORMIN HYDROCHLORIDE 250 mg/1Jul 15, 2026Sep 2, 2026
Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.GLYBURIDE 2.5 mg/1; METFORMIN HYDROCHLORIDE 500 mg/1Jul 15, 2026Sep 2, 2026
Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.GLYBURIDE 5 mg/1; METFORMIN HYDROCHLORIDE 500 mg/1Jul 15, 2026Sep 2, 2026
NuCare Pharmaceuticals, Inc.GLYBURIDE 5 mg/1; METFORMIN HYDROCHLORIDE 500 mg/1Jul 15, 2026Sep 2, 2026
Preferred Pharmaceuticals Inc.GLYBURIDE 5 mg/1; METFORMIN HYDROCHLORIDE 500 mg/1Jul 15, 2026Sep 2, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "glyburide-metformin hydrochloride — NDC 23155-0233-01," retrieved September 3, 2026, https://drugdashboards.com/drug/23155023301.

Free to cite with attribution — see how the data is put together.