DrugDashboards

pentamidine isethionate

pentamidine isethionate · PENTAMIDINE ISETHIONATE 300 mg/300mg · Injection, Powder, Lyophilized, For Solution · Intramuscular; Intravenous · Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.

NDC 23155-0748-41 · 10 VIAL, SINGLE-DOSE in 1 CARTON / 300 mg in 1 VIAL, SINGLE-DOSE · ANDA · View full market →

The short version

5 companies supply this market — a reasonable cushion if one runs into trouble. One of its named manufacturing plants, Immacule Lifesciences Private Limited, failed FDA inspectionwithin the last two years — the agency’s most serious outcome.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Medicare Part B pays (ASP+6%)$0.1600per billing unit (1 MG)HCPCS J2516 · Jul 1, 2026
  • Part D plans paid (avg)$114.16per dosage unitgross, before rebates — matched by drug name · 2024

Medicare Part D

All Part D pricing →

Matched to CMS's representative package for this drug (NDC 13925-0515-10) — same generic, strength, and dosage form. CMS prices one NDC per drug concept, not every package.

ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$113.86per unit
middle half $97.52$118.92 · 5,496 plans · Apr 1, 2026
Est. net of rebates
≈ $113.86
generic — rebates are minimal, so net ≈ gross
Coverage & restrictions
100%of plans cover it
tier 4 · prior auth 1% · step therapy 0% · qty limit 0%

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.

NADAC price per unit

No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.

Estimated fill cost

WAC per package, as filed
$977.00
Reported to Texas DSHS · 2026 annual filing · Heritage Pharmaceuticals, Inc. d/b/a Avet Pharmaceuticals

Manufacturer list price as filed — not what pharmacies actually pay after discounts.

Medicare Part B (ASP)

Payment limit per 1 MG
$0.160
HCPCS J2516 · Jul 1, 2026 quarter · typically ASP + 6%

Medicaid spend (2025)

$12,086
120 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

Not scored — fragility is computed for NADAC-priced NDCs.

Where it's made

Establishments this product's FDA label declares, located via FDA registration data. How we built this →

Is this a "specialty" drug?

There's no legal definition — it meets 1 of 6 public criteria. Why that matters →

  • Part D specialty tier
  • Costs ≥ $950/fill · avg $123.78 per prescription
  • Biologic (BLA)
  • Injectable / infused
  • Orphan-drug exclusivity
  • REMS program

Regulatory

Application
ANDA213806
TE code
AP
Approval date
Jan 7, 2021
Patents / exclusivity
None on file

Shortage history

  • Planned discontinuation Pentamidine Isethionate, Injection, 300 mg/3 mL (NDC 39822-3050-2)Mar 23, 2026

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of pentamidine isethionate (Injection, Powder, Lyophilized, For Solution)

LabelerStrengthFirst seenLast seen
Fresenius Kabi USA, LLCPENTAMIDINE ISETHIONATE 300 mg/3mLJul 15, 2026Sep 2, 2026
Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.PENTAMIDINE ISETHIONATE 300 mg/300mgJul 15, 2026Sep 2, 2026
PAI Holdings, LLC dba PAI PharmaPENTAMIDINE DIISETHIONATE 300 mg/300mgJul 15, 2026Sep 2, 2026
Seton PharmaceuticalsPENTAMIDINE ISETHIONATE 300 mg/300mgJul 15, 2026Sep 2, 2026
XGen Pharmaceuticals DJB, Inc.PENTAMIDINE ISETHIONATE 300 mg/3mLJul 15, 2026Sep 2, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "pentamidine isethionate — NDC 23155-0748-41," retrieved September 3, 2026, https://drugdashboards.com/drug/23155074841.

Free to cite with attribution — see how the data is put together.