DrugDashboards

Piperacillin, Tazobactam

Piperacillin Sodium, Tazobactam Sodium · PIPERACILLIN SODIUM 36 g/152mL; TAZOBACTAM SODIUM 4.5 g/152mL · Injection, Powder, Lyophilized, For Solution · Intravenous · Sagent Pharmaceuticals

NDC 25021-0181-99 · 1 BOTTLE in 1 CARTON / 152 mL in 1 BOTTLE · ANDA · View full market →

The short version

Only one company currently supplies this market — there is no backup if it stumbles. Historically, drugs in this position went on to a new shortage within 90 days about 0.5% of the time — roughly 4× the typical drug (0.1%).

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

Medicare Part D

No Medicare Part D plan in CMS's quarterly files lists this product. That usually means it is discontinued, a repackager's listing, or a product no plan has added to its formulary.

How Part D pricing works →

NADAC price per unit

No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.

Estimated fill cost

WAC per package, as filed
$65.00
Reported to Texas DSHS · 2026 annual filing · Sagent Pharmaceuticals

Manufacturer list price as filed — not what pharmacies actually pay after discounts.

Medicare Part B (ASP)

Payment limit per 1.125 GM
$1.218
HCPCS J2543 · Jul 1, 2026 quarter · typically ASP + 6%

Medicaid spend (2025)

$16,205
303 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

Not scored — fragility is computed for NADAC-priced NDCs.

90-day shortage risk (model v2)

0.5%chance of a new FDA shortage posting for piperacillin sodium and tazobactam sodium (injectable) in the next 90 days

sterile injectable · OAI inspection at a producing facility (24 months) · sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is 4× that.

Backtested statistical model over the whole market, not this package alone. Model details →

Is this a "specialty" drug?

There's no legal definition — it meets 1 of 6 public criteria. Why that matters →

  • Part D specialty tier
  • Costs ≥ $950/fill
  • Biologic (BLA)
  • Injectable / infused
  • Orphan-drug exclusivity
  • REMS program

Regulatory

Application
ANDA208675
TE code
AP
Approval date
Feb 16, 2021
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of Piperacillin Sodium, Tazobactam Sodium (Injection, Powder, Lyophilized, For Solution)

LabelerStrengthFirst seenLast seen
Sagent PharmaceuticalsPIPERACILLIN SODIUM 36 g/152mL; TAZOBACTAM SODIUM 4.5 g/152mLJul 15, 2026Sep 2, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Piperacillin, Tazobactam — NDC 25021-0181-99," retrieved September 3, 2026, https://drugdashboards.com/drug/25021018199.

Free to cite with attribution — see how the data is put together.