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Tolak

Fluorouracil · FLUOROURACIL .04 g/g · Cream · Topical · Hill Dermaceuticals, Inc.

NDC 28105-0421-40 · 1 TUBE in 1 CARTON / 40 g in 1 TUBE · NDA · View full market →

The short version

9 companies supply this market — a reasonable cushion if one runs into trouble. The price has jumped 75% in a year, to $6.42 per unit — sharp rises like this often mean supply is already tightening.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

Medicare Part D

No Medicare Part D plan in CMS's quarterly files lists this product. That usually means it is discontinued, a repackager's listing, or a product no plan has added to its formulary.

How Part D pricing works →

NADAC price per unit

$0$2.50$5.00$7.50Dec 2016Jan 2018$6.42
3 price points · per · last surveyed Invalid DateSource: CMS NADAC

Estimated fill cost

Estimated WAC per estimate
$6.617
No Texas or California filing exists for this NDC — this figure is derived, not filed.

This is an ESTIMATE derived from NADAC, not a filed or published price: pharmacies typically acquire brand drugs at roughly 2–4% below list, so list ≈ NADAC ÷ 0.97. Shown only because no state transparency filing exists for this NDC.

Supply fragility

Not scored — fragility is computed for NADAC-priced NDCs.

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for fluorouracil (other) in the next 90 days

sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Where it's made

Establishments this product's FDA label declares, located via FDA registration data. How we built this →

Regulatory

Application
NDA022259
TE code
Approval date
Sep 18, 2015
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of Fluorouracil (Cream)

LabelerStrengthFirst seenLast seen
Accord Healthcare Inc.FLUOROURACIL 50 mg/gJul 15, 2026Sep 2, 2026
Bausch Health US, LLCFLUOROURACIL 2 g/40gJul 15, 2026Sep 2, 2026
Dr. Reddy's Labratories Inc.FLUOROURACIL 50 mg/gJul 15, 2026Sep 2, 2026
Encube Ethicals, Inc.FLUOROURACIL 2 g/40gJul 15, 2026Sep 2, 2026
Hill Dermaceuticals, Inc.FLUOROURACIL .04 g/gJul 15, 2026Sep 2, 2026
Mayne Pharma Inc.FLUOROURACIL 50 mg/gJul 15, 2026Sep 2, 2026
Mylan Pharmaceuticals Inc.FLUOROURACIL 5 mg/gJul 15, 2026Sep 2, 2026
Northstar Rx LlcFLUOROURACIL 50 mg/gJul 15, 2026Sep 2, 2026
Sun Pharmaceutical Industries, Inc.FLUOROURACIL 50 mg/gJul 18, 2026Aug 29, 2026
Taro Pharmaceuticals U.S.A., Inc.FLUOROURACIL 50 mg/gJul 15, 2026Jul 15, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Tolak — NDC 28105-0421-40," retrieved September 3, 2026, https://drugdashboards.com/drug/28105042140.

Free to cite with attribution — see how the data is put together.