DrugDashboards

Histex-Dm

DEXTROMETHORPHAN HYDROBROMIDE, PHENYLEPHRINE HYDROCHLORIDE, and TRIPROLIDINE HYDROCHLORIDE · DEXTROMETHORPHAN HYDROBROMIDE 20 mg/5mL; PHENYLEPHRINE HYDROCHLORIDE 10 mg/5mL; TRIPROLIDINE HYDROCHLORIDE 2.5 mg/5mL · Syrup · Oral · Allegis Pharmaceuticals, LLC

NDC 28595-0804-16 · 473 mL in 1 BOTTLE · OTC MONOGRAPH DRUG · View full market →

The short version

Only one company currently supplies this market — there is no backup if it stumbles. The price has held steady around $0.0739 per mL over the past year. Put together: worth watching — several of the pressures that precede supply trouble are present at once.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

Medicare Part D

Medicare Part D does not cover over-the-counter drugs — by law it pays only for products requiring a prescription.

How Part D pricing works →

NADAC price per unit

$0$0.025$0.05$0.075Jan 2018Sep 2026$0.0739
17 price points · per MLSource: CMS NADAC

Estimated fill cost

WAC per package, as filed
$32.99
Reported to Texas DSHS · 2025 annual filing · Allegis Pharmaceuticals, LLC

Manufacturer list price as filed — not what pharmacies actually pay after discounts.

Medicaid spend (2025)

$128,780
13,022 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

30Elevated risk

The score is counting real pressure here. One of these alone is routine; it’s the combination that makes this market worth watching.

  • 1 active manufacturer+30

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for dextromethorphan hydrobromide, phenylephrine hydrochloride, and triprolidine hydrochloride (other) in the next 90 days

price up 4% YoY

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Regulatory

Application
M012
TE code
Approval date
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of DEXTROMETHORPHAN HYDROBROMIDE, PHENYLEPHRINE HYDROCHLORIDE, and TRIPROLIDINE HYDROCHLORIDE (Syrup)

LabelerStrengthFirst seenLast seen
Allegis Pharmaceuticals, LLCDEXTROMETHORPHAN HYDROBROMIDE 20 mg/5mL; PHENYLEPHRINE HYDROCHLORIDE 10 mg/5mL; TRIPROLIDINE HYDROCHLORIDE 2.5 mg/5mLJul 15, 2026Sep 2, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Histex-Dm — NDC 28595-0804-16," retrieved September 3, 2026, https://drugdashboards.com/drug/28595080416.

Free to cite with attribution — see how the data is put together.