DrugDashboards

Sacubitril and valsartan

Sacubitril and valsartan · SACUBITRIL 49 mg/1; VALSARTAN 51 mg/1 · Tablet, Film Coated · Oral · Camber Pharmaceuticals, Inc.

NDC 31722-0674-18 · 180 TABLET, FILM COATED in 1 BOTTLE · ANDA · View full market →

The short version

17 companies supply this market — deep enough that no single failure threatens the supply. The generic price has fallen 55% in a year, to $0.5291 per unit — and generics that get this cheap tend to get abandoned rather than defended. The brand (Entresto) runs $11.59 per unit 22× more. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$0.5291per EAinvoice-surveyed acquisition cost · Aug 19, 2026
  • Medicaid generic ceiling (FUL)$1.12per TABweighted avg manufacturer price $0.6397 · Aug 1, 2026212% of what pharmacies pay — higher than 90% of drugs with this benchmark

Medicare Part D

All Part D pricing →

Matched to CMS's representative package for this drug (NDC 00078-0777-20) — same generic, strength, and dosage form. CMS prices one NDC per drug concept, not every package.

ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$5.23per unit
middle half $5.23$5.23 · 393 plans · Apr 1, 2026
Est. net of rebates
≈ $5.23
generic — rebates are minimal, so net ≈ gross
Coverage & restrictions
7%of plans cover it
tier 3 · prior auth 0% · step therapy 25% · qty limit 97%

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.

NADAC price per unit

$0$2.50$5.00$7.50Sep 2025Sep 2026$0.5291
12 price points · per EA · dashed = manufacturer avg (WAMP)Source: CMS NADAC

Estimated fill cost

#30 count
$15.87
#90 count
$47.62

Estimates: latest NADAC unit price × quantity. Pharmacy acquisition cost only — excludes dispensing fees, markup, and insurance terms.

Medicaid spend (2025)

$1,198
14 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

0Low risk

Nothing here is signaling trouble: several manufacturers, no current shortage, no recent serious recalls, stable pricing. In drug supply, boring is the good outcome.

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for sacubitril and valsartan (oral solid) in the next 90 days

sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Where it's made

Establishments this product's FDA label declares, located via FDA registration data. How we built this →

Regulatory

Application
ANDA213668
TE code
AB
Approval date
Jul 17, 2025
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of Sacubitril and valsartan (Tablet, Film Coated)

LabelerStrengthFirst seenLast seen
Aphena Pharma Solutions - Tennessee, LLCSACUBITRIL 49 mg/1; VALSARTAN 51 mg/1Jul 15, 2026Sep 3, 2026
Aphena Pharma Solutions - Tennessee, LLCSACUBITRIL 97 mg/1; VALSARTAN 103 mg/1Jul 15, 2026Sep 3, 2026
Ascend Laboratories, LLCSACUBITRIL 97 mg/1; VALSARTAN 103 mg/1Jul 15, 2026Sep 3, 2026
AvKARESACUBITRIL 97 mg/1; VALSARTAN 103 mg/1Jul 15, 2026Sep 3, 2026
Novartis Pharmaceuticals CorporationSACUBITRIL 49 mg/1; VALSARTAN 51 mg/1Jul 15, 2026Sep 3, 2026
Novugen Pharma (USA) LLCSACUBITRIL 97 mg/1; VALSARTAN 103 mg/1Jul 15, 2026Sep 3, 2026
Synthon Chile LimitadaVALSARTAN DISODIUM 103 mg/1; SACUBITRIL SODIUM 97 mg/1Aug 20, 2026Sep 3, 2026
Synthon Chile LimitadaVALSARTAN DISODIUM 51 mg/1; SACUBITRIL SODIUM 49 mg/1Aug 20, 2026Sep 3, 2026
Alembic Pharmaceuticals Inc.SACUBITRIL 49 mg/1; VALSARTAN 51 mg/1Jul 15, 2026Sep 2, 2026
Alembic Pharmaceuticals Inc.SACUBITRIL 97 mg/1; VALSARTAN 103 mg/1Jul 15, 2026Sep 2, 2026
Alembic Pharmaceuticals Inc.SACUBITRIL 24 mg/1; VALSARTAN 26 mg/1Jul 15, 2026Sep 2, 2026
Alembic Pharmaceuticals LimitedSACUBITRIL 49 mg/1; VALSARTAN 51 mg/1Jul 15, 2026Sep 2, 2026
Alembic Pharmaceuticals LimitedSACUBITRIL 24 mg/1; VALSARTAN 26 mg/1Jul 15, 2026Sep 2, 2026
Alembic Pharmaceuticals LimitedSACUBITRIL 97 mg/1; VALSARTAN 103 mg/1Jul 15, 2026Sep 2, 2026
American Health PackagingSACUBITRIL 97 mg/1; VALSARTAN 103 mg/1Jul 15, 2026Sep 2, 2026
American Health PackagingSACUBITRIL 49 mg/1; VALSARTAN 51 mg/1Jul 15, 2026Sep 2, 2026
American Health PackagingSACUBITRIL 24 mg/1; VALSARTAN 26 mg/1Jul 15, 2026Sep 2, 2026
Amneal Pharmaceuticals NY LLCSACUBITRIL 49 mg/1; VALSARTAN 51 mg/1Jul 15, 2026Sep 2, 2026
Amneal Pharmaceuticals NY LLCSACUBITRIL 97 mg/1; VALSARTAN 103 mg/1Jul 15, 2026Sep 2, 2026
Amneal Pharmaceuticals NY LLCSACUBITRIL 24 mg/1; VALSARTAN 26 mg/1Jul 15, 2026Sep 2, 2026
ANI Pharmaceuticals, Inc.SACUBITRIL 24 mg/1; VALSARTAN 26 mg/1Jul 15, 2026Sep 2, 2026
ANI Pharmaceuticals, Inc.SACUBITRIL 97 mg/1; VALSARTAN 103 mg/1Jul 15, 2026Sep 2, 2026
ANI Pharmaceuticals, Inc.SACUBITRIL 49 mg/1; VALSARTAN 51 mg/1Jul 15, 2026Sep 2, 2026
Ascend Laboratories, LLCSACUBITRIL 24 mg/1; VALSARTAN 26 mg/1Jul 15, 2026Sep 2, 2026
AvKARESACUBITRIL 49 mg/1; VALSARTAN 51 mg/1Jul 15, 2026Sep 2, 2026
AvKAREVALSARTAN 51 mg/1; SACUBITRIL 49 mg/1Aug 26, 2026Sep 2, 2026
AvPAKSACUBITRIL 24 mg/1; VALSARTAN 26 mg/1Jul 15, 2026Sep 2, 2026
AvPAKSACUBITRIL 49 mg/1; VALSARTAN 51 mg/1Jul 15, 2026Sep 2, 2026
AvPAKSACUBITRIL 97 mg/1; VALSARTAN 103 mg/1Jul 15, 2026Sep 2, 2026
Biocon Pharma Inc.SACUBITRIL 97 mg/1; VALSARTAN 103 mg/1Jul 15, 2026Sep 2, 2026
Biocon Pharma Inc.SACUBITRIL 24 mg/1; VALSARTAN 26 mg/1Jul 15, 2026Sep 2, 2026
Biocon Pharma Inc.SACUBITRIL 49 mg/1; VALSARTAN 51 mg/1Jul 15, 2026Sep 2, 2026
Camber Pharmaceuticals, Inc.SACUBITRIL 24 mg/1; VALSARTAN 26 mg/1Jul 15, 2026Sep 2, 2026
Camber Pharmaceuticals, Inc.SACUBITRIL 97 mg/1; VALSARTAN 103 mg/1Jul 15, 2026Sep 2, 2026
Camber Pharmaceuticals, Inc.SACUBITRIL 49 mg/1; VALSARTAN 51 mg/1Jul 15, 2026Sep 2, 2026
Coupler LLCSACUBITRIL 24 mg/1; VALSARTAN 26 mg/1Jul 15, 2026Sep 2, 2026
Dr. Reddy's Laboratories Inc.SACUBITRIL 49 mg/1; VALSARTAN 51 mg/1Jul 15, 2026Sep 2, 2026
Dr. Reddy's Laboratories Inc.SACUBITRIL 97 mg/1; VALSARTAN 103 mg/1Jul 15, 2026Sep 2, 2026
Dr. Reddy's Laboratories Inc.SACUBITRIL 24 mg/1; VALSARTAN 26 mg/1Jul 15, 2026Sep 2, 2026
Golden State Medical Supply, Inc.SACUBITRIL 97 mg/1; VALSARTAN 103 mg/1Jul 15, 2026Sep 2, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Sacubitril and valsartan — NDC 31722-0674-18," retrieved September 3, 2026, https://drugdashboards.com/drug/31722067418.

Free to cite with attribution — see how the data is put together.