The short version
Just 2 companies supply this market — thin enough that a single exit would be felt immediately.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
NyQuil Severe plus Vicks VapoCool Cold and Flu
Acetaminophen, Phenylephrine Hydrochloride, Doxylamine Succinate, and Dextromethorphan Hydrobromide · DEXTROMETHORPHAN HYDROBROMIDE 10 mg/1; ACETAMINOPHEN 325 mg/1; PHENYLEPHRINE HYDROCHLORIDE 5 mg/1; DOXYLAMINE SUCCINATE 6.25 mg/1 · Tablet, Coated · Oral · The Procter & Gamble Manufacturing Company
NDC 37000-0523-02 · 2 TABLET, COATED in 1 POUCH · OTC MONOGRAPH DRUG · View full market →
Medicare Part D
Medicare Part D does not cover over-the-counter drugs — by law it pays only for products requiring a prescription.
How Part D pricing works →NADAC price per unit
No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.
Supply fragility
Not scored — fragility is computed for NADAC-priced NDCs.
Is this a "specialty" drug?
There's no legal definition — it meets 1 of 6 public criteria. Why that matters →
- Part D specialty tier
- Costs ≥ $950/fill
- Biologic (BLA)
- Injectable / infused
- Orphan-drug exclusivity
- REMS program · Opioid Analgesic REMS Shared System REMS
Regulatory
- Application
- M012
- TE code
- —
- Approval date
- —
- Patents / exclusivity
- None on file
Shortage history
No FDA shortage reports for this drug or its presentations.
Recalls (this NDC)
No enforcement reports list this package NDC.
Manufacturers of Acetaminophen, Phenylephrine Hydrochloride, Doxylamine Succinate, and Dextromethorphan Hydrobromide (Tablet, Coated)
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| Lil' Drug Store Products, Inc. | ACETAMINOPHEN 325 mg/1; PHENYLEPHRINE HYDROCHLORIDE 5 mg/1; DOXYLAMINE SUCCINATE 6.25 mg/1; DEXTROMETHORPHAN HYDROBROMIDE 10 mg/1 | Aug 26, 2026 | Sep 3, 2026 |
| The Procter & Gamble Manufacturing Company | ACETAMINOPHEN 325 mg/1; PHENYLEPHRINE HYDROCHLORIDE 5 mg/1; DOXYLAMINE SUCCINATE 6.25 mg/1; DEXTROMETHORPHAN HYDROBROMIDE 10 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| The Procter & Gamble Manufacturing Company | DEXTROMETHORPHAN HYDROBROMIDE 10 mg/1; ACETAMINOPHEN 325 mg/1; PHENYLEPHRINE HYDROCHLORIDE 5 mg/1; DOXYLAMINE SUCCINATE 6.25 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Lil' Drug Store Products, Inc. | ACETAMINOPHEN 325 mg/1; PHENYLEPHRINE HYDROCHLORIDE 10 mg/1; DOXYLAMINE SUCCINATE 6.25 mg/1; DEXTROMETHORPHAN HYDROBROMIDE 5 mg/1 | Jul 22, 2026 | Aug 22, 2026 |
| The Procter & Gamble Manufacturing Company | DEXTROMETHORPHAN HYDROBROMIDE 325 mg/1; ACETAMINOPHEN 10 mg/1; PHENYLEPHRINE HYDROCHLORIDE 6.25 mg/1; DOXYLAMINE SUCCINATE 5 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| The Procter & Gamble Manufacturing Company | ACETAMINOPHEN 325 mg/1; PHENYLEPHRINE HYDROCHLORIDE 10 mg/1; DOXYLAMINE SUCCINATE 6.25 mg/1; DEXTROMETHORPHAN HYDROBROMIDE 5 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Lil' Drug Store Products, Inc. | ACETAMINOPHEN 325 mg/1; DEXTROMETHORPHAN HYDROBROMIDE 10 mg/1; DOXYLAMINE SUCCINATE 6.25 mg/1; PHENYLEPHRINE HYDROCHLORIDE 5 mg/1 | Jul 15, 2026 | Jul 19, 2026 |
| The Procter & Gamble Manufacturing Company | ACETAMINOPHEN 325 mg/1; DEXTROMETHORPHAN HYDROBROMIDE 10 mg/1; DOXYLAMINE SUCCINATE 6.25 mg/1; PHENYLEPHRINE HYDROCHLORIDE 5 mg/1 | Jul 15, 2026 | Jul 16, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
Cite this page
DrugDashboards, "NyQuil Severe plus Vicks VapoCool Cold and Flu — NDC 37000-0523-02," retrieved September 3, 2026, https://drugdashboards.com/drug/37000052302.
Free to cite with attribution — see how the data is put together.