The short version
5 companies supply this market — a reasonable cushion if one runs into trouble.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
Severe Cold and Flu Nighttime Honey
Acetaminophen, Dextromethorphan HBr, Doxylamine succinate, Phenylephrine HCl · DEXTROMETHORPHAN HYDROBROMIDE 10 mg/15mL; PHENYLEPHRINE HYDROCHLORIDE 5 mg/15mL; DOXYLAMINE SUCCINATE 6.25 mg/15mL; ACETAMINOPHEN 325 mg/15mL · Liquid · Oral · Kroger
NDC 41226-0767-01 · 354 mL in 1 BOTTLE · OTC MONOGRAPH DRUG · View full market →
Medicare Part D
Medicare Part D does not cover over-the-counter drugs — by law it pays only for products requiring a prescription.
How Part D pricing works →NADAC price per unit
No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.
Supply fragility
Not scored — fragility is computed for NADAC-priced NDCs.
90-day shortage risk (model v2)
0.1%chance of a new FDA shortage posting for acetaminophen, dextromethorphan hbr, doxylamine succinate, phenylephrine hcl (other) in the next 90 days
sole-source market
For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.
Backtested statistical model over the whole market, not this package alone. Model details →
Is this a "specialty" drug?
There's no legal definition — it meets 1 of 6 public criteria. Why that matters →
- Part D specialty tier
- Costs ≥ $950/fill
- Biologic (BLA)
- Injectable / infused
- Orphan-drug exclusivity
- REMS program · Opioid Analgesic REMS Shared System REMS
Regulatory
- Application
- M012
- TE code
- —
- Approval date
- —
- Patents / exclusivity
- None on file
Shortage history
No FDA shortage reports for this drug or its presentations.
Recalls (this NDC)
No enforcement reports list this package NDC.
Manufacturers of Acetaminophen, Dextromethorphan HBr, Doxylamine succinate, Phenylephrine HCl (Liquid)
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| Efficient Laboratories Inc | ACETAMINOPHEN 650 mg/30mL; DEXTROMETHORPHAN HYDROBROMIDE 20 mg/30mL; DOXYLAMINE SUCCINATE 12.5 mg/30mL; PHENYLEPHRINE HYDROCHLORIDE 10 mg/30mL | Jul 15, 2026 | Sep 2, 2026 |
| Grocery Outlet, Inc. | DOXYLAMINE SUCCINATE 12.5 mg/30mL; PHENYLEPHRINE HYDROCHLORIDE 10 mg/30mL; ACETAMINOPHEN 650 mg/30mL; DEXTROMETHORPHAN HYDROBROMIDE 20 mg/30mL | Aug 26, 2026 | Sep 2, 2026 |
| Kroger | DOXYLAMINE SUCCINATE 12.5 mg/30mL; PHENYLEPHRINE HYDROCHLORIDE 10 mg/30mL; ACETAMINOPHEN 650 mg/30mL; DEXTROMETHORPHAN HYDROBROMIDE 20 mg/30mL | Aug 26, 2026 | Sep 2, 2026 |
| Kroger | DEXTROMETHORPHAN HYDROBROMIDE 10 mg/15mL; PHENYLEPHRINE HYDROCHLORIDE 5 mg/15mL; DOXYLAMINE SUCCINATE 6.25 mg/15mL; ACETAMINOPHEN 325 mg/15mL | Aug 26, 2026 | Sep 2, 2026 |
| Target Corporation | DEXTROMETHORPHAN HYDROBROMIDE 20 mg/30mL; ACETAMINOPHEN 650 mg/30mL; DOXYLAMINE SUCCINATE 12.5 mg/30mL; PHENYLEPHRINE HYDROCHLORIDE 10 mg/30mL | Aug 26, 2026 | Sep 2, 2026 |
| Walgreen Company | ACETAMINOPHEN 650 mg/30mL; DEXTROMETHORPHAN HYDROBROMIDE 20 mg/30mL; DOXYLAMINE SUCCINATE 12.5 mg/30mL; PHENYLEPHRINE HYDROCHLORIDE 10 mg/30mL | Jul 15, 2026 | Sep 2, 2026 |
| Grocery Outlet, Inc. | DOXYLAMINE SUCCINATE 650 mg/30mL; PHENYLEPHRINE HYDROCHLORIDE 20 mg/30mL; ACETAMINOPHEN 12.5 mg/30mL; DEXTROMETHORPHAN HYDROBROMIDE 10 mg/30mL | Jul 22, 2026 | Aug 19, 2026 |
| Kroger | DOXYLAMINE SUCCINATE 650 mg/30mL; PHENYLEPHRINE HYDROCHLORIDE 20 mg/30mL; ACETAMINOPHEN 12.5 mg/30mL; DEXTROMETHORPHAN HYDROBROMIDE 10 mg/30mL | Jul 22, 2026 | Aug 19, 2026 |
| Kroger | DEXTROMETHORPHAN HYDROBROMIDE 325 mg/15mL; PHENYLEPHRINE HYDROCHLORIDE 10 mg/15mL; DOXYLAMINE SUCCINATE 6.25 mg/15mL; ACETAMINOPHEN 5 mg/15mL | Jul 22, 2026 | Aug 19, 2026 |
| Target Corporation | DEXTROMETHORPHAN HYDROBROMIDE 650 mg/30mL; ACETAMINOPHEN 20 mg/30mL; DOXYLAMINE SUCCINATE 12.5 mg/30mL; PHENYLEPHRINE HYDROCHLORIDE 10 mg/30mL | Jul 22, 2026 | Aug 19, 2026 |
| Grocery Outlet, Inc. | ACETAMINOPHEN 650 mg/30mL; DEXTROMETHORPHAN HYDROBROMIDE 20 mg/30mL; DOXYLAMINE SUCCINATE 12.5 mg/30mL; PHENYLEPHRINE HYDROCHLORIDE 10 mg/30mL | Jul 15, 2026 | Jul 15, 2026 |
| Kroger | ACETAMINOPHEN 650 mg/30mL; DEXTROMETHORPHAN HYDROBROMIDE 20 mg/30mL; DOXYLAMINE SUCCINATE 12.5 mg/30mL; PHENYLEPHRINE HYDROCHLORIDE 10 mg/30mL | Jul 15, 2026 | Jul 15, 2026 |
| Kroger | ACETAMINOPHEN 325 mg/15mL; DEXTROMETHORPHAN HYDROBROMIDE 10 mg/15mL; DOXYLAMINE SUCCINATE 6.25 mg/15mL; PHENYLEPHRINE HYDROCHLORIDE 5 mg/15mL | Jul 15, 2026 | Jul 15, 2026 |
| Target Corporation | ACETAMINOPHEN 650 mg/30mL; DEXTROMETHORPHAN HYDROBROMIDE 20 mg/30mL; DOXYLAMINE SUCCINATE 12.5 mg/30mL; PHENYLEPHRINE HYDROCHLORIDE 10 mg/30mL | Jul 15, 2026 | Jul 15, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
Cite this page
DrugDashboards, "Severe Cold and Flu Nighttime Honey — NDC 41226-0767-01," retrieved September 3, 2026, https://drugdashboards.com/drug/41226076701.
Free to cite with attribution — see how the data is put together.